Results 81 to 90 of about 4,551,719 (377)
Phage Therapy: Concept to Cure [PDF]
The development and mass-production of antibiotics ranks as one of the twentieth cen-tury’s greatest scientific achievements. For more than 60 years, antibiotics have com-prised Western medicine’s primary defense against bacterial disease. But although antibiotics have saved millions of lives, our chemical shield has become increasingly leaky.
openaire +4 more sources
Phage therapy: progress in pharmacokinetics [PDF]
ABSTRACT The concept of phage therapy exists in the history and it has been ignored for a long time, but the consequence of drug resistance in pathogen bacteria has forced the forgotten kingdom of phage therapy to be re-explored. However, for the successful implementation and acceptance of phage therapy worldwide, the number of factors need to be ...
Qadir, Muhammad Imran+2 more
openaire +5 more sources
Chromosomal DNA deletion confers phage resistance to Pseudomonas aeruginosa. [PDF]
Bacteria develop a broad range of phage resistance mechanisms, such as prevention of phage adsorption and CRISPR/Cas system, to survive phage predation.
He, Xuesong+13 more
core +1 more source
Bacteriophage therapy is the use of viruses to kill bacteria for the treatment of antibiotic-resistant infections. Little is known about the human immune response following phage therapy. We report the development of phage-specific CD4+ T cells alongside
J. Dan+13 more
semanticscholar +1 more source
Phage therapies for plants and people [PDF]
The use of bacteriophages to combat bacterial infections may help to address the current crisis of antibiotic resistance. Fundamental issues arising from the ecological dynamic of host, bacterium and phage can be investigated in trees, offering both a natural approach to treating plant disease, and a chance to avoid creating a new resistance problem ...
openaire +3 more sources
Phages and phage therapy: past, present and future
Bacteriophages are viruses that infect bacteria. Since their discovery in the last century, they have proved their effectiveness in biocontrol of bacteria. In this mini-review, we provide a brief history of bacteriophages, their life cycle and classification.
Essa, Nour+2 more
openaire +3 more sources
The appearance of bacteria resistant to most or even all known antibiotics has become a serious medical problem. One such promising and effective alternative form of therapy may be the use of phages, the administration of which is considered to be safe ...
Łukasz Grabowski+3 more
doaj +1 more source
The preclinical and clinical progress of bacteriophages and their lytic enzymes : the parts are easier than the whole [PDF]
The therapeutic potential of phages has been considered since their first identification more than a century ago. The evident concept of using a natural predator to treat bacterial infections has, however, since then been challenged considerably ...
Abdelkader, Karim Abdelkader Soufi+4 more
core +1 more source
Acinetobacter baumannii is a multidrug-resistant and invasive pathogen associated with the etiopathology of both an increasing number of nosocomial infections and is of relevance to poultry production systems.
Yan Zhang+14 more
semanticscholar +1 more source
Contamination with bacteria and organic matters is becoming a serious challenge for governments and a central issue for public health. Biosynthesized silver nanoparticles (AgNPs) are currently gaining attention due to the additional properties provided ...
Salsabil Makky+10 more
doaj