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Bacteriophages can be used successfully to treat pathogenic bacteria in the food chain including zoonotic pathogens that colonize the intestines of farm animals.
Abdallah S. Abdelsattar+4 more
doaj +1 more source
Phage therapy of wound-associated infections
Phages are viruses which can specifically infect bacteria, resulting in their destruction. Bacterial infections are a common complication of wound healing, and experimental evidence from animal models demonstrates promising potential for phage-dependent ...
A. Zyman, A. Górski, R. Międzybrodzki
semanticscholar +1 more source
Phage therapy is recognized as a promising alternative to antibiotics in treating pulmonary bacterial infections, however, its use has not been reported for treating secondary bacterial infections during virus pandemics such as coronavirus disease 2019 ...
Nannan Wu+33 more
semanticscholar +1 more source
Bacteriophage-mediated competition in Bordetella bacteria [PDF]
Apparent competition between species is believed to be one of the principle driving forces that structure ecological communities, although the precise mecha nisms have yet to be characterized. Here we develop a model system that isolates phage-mediated interactions by neutralizing resource competition using two genetically identical Bordetella ...
arxiv +1 more source
Diversity and function of phage encoded depolymerases [PDF]
Bacteriophages of the Podoviridae family often exhibit so-called depolymerases as structural components of the virion. These enzymes appear as tail spike proteins (TSPs).
Fieseler, Lars+2 more
core +1 more source
Bacteriophage therapy is the use of viruses to kill bacteria for the treatment of antibiotic-resistant infections. Little is known about the human immune response following phage therapy. We report the development of phage-specific CD4+ T cells alongside
J. Dan+13 more
semanticscholar +1 more source
Phage Therapy: Concept to Cure [PDF]
The development and mass-production of antibiotics ranks as one of the twentieth cen-tury’s greatest scientific achievements. For more than 60 years, antibiotics have com-prised Western medicine’s primary defense against bacterial disease. But although antibiotics have saved millions of lives, our chemical shield has become increasingly leaky.
openaire +4 more sources
The Promising Viral Threat to Bacterial Resistance: The Uncertain Patentability of Phage Therapeutics and the Necessity of Alternative Incentives [PDF]
Bacteriophages, or “phages,” are a category of highly adept and adaptable viruses that can infect and kill bacteria. With concerns over the burgeoning antibiotic-resistance crisis looming in recent years, scientists and policymakers have expressed a ...
Todd, Kelly
core +2 more sources
The Medicinal Phage—Regulatory Roadmap for Phage Therapy under EU Pharmaceutical Legislation
Bacteriophage therapy is a promising approach to treating bacterial infections. Research and development of bacteriophage therapy is intensifying due to the increase in antibiotic resistance and the faltering development of new antibiotics. Bacteriophage
Timo Faltus
semanticscholar +1 more source
Phage therapies for plants and people [PDF]
The use of bacteriophages to combat bacterial infections may help to address the current crisis of antibiotic resistance. Fundamental issues arising from the ecological dynamic of host, bacterium and phage can be investigated in trees, offering both a natural approach to treating plant disease, and a chance to avoid creating a new resistance problem ...
openaire +3 more sources