Results 11 to 20 of about 74,832 (169)
Adapting a Phage to Combat Phage Resistance [PDF]
Phage therapy is becoming a widely recognized alternative for fighting pathogenic bacteria due to increasing antibiotic resistance problems. However, one of the common concerns related to the use of phages is the evolution of bacterial resistance against the phages, putatively disabling the treatment.
Mäkelä, Kati +5 more
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Phages and Immunomodulation [PDF]
In the past years, the microbiome and its role in the pathophysiology of diseases have gained great interest. The progress of our knowledge in this field opens completely novel prospects for treating disorders, including those which are most challenging to medicine today.
Andrzej, Górski +6 more
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We report a detailed characterization of five thermophilic bacteriophages (phages) that were isolated from compost heaps in Vilnius, Lithuania using Geobacillus thermodenitrificans strains as the hosts for phage propagation.
Eugenijus Šimoliūnas +8 more
doaj +1 more source
Model microbial communities are often studied to better understand interactions and fluxes during fermentation processes. However, models that take into account the potential impact of bacteriophages (phages), which are recognized as drivers of microbial
Pierre Ledormand +5 more
doaj +1 more source
Impact of Bacteriophage-Supplemented Drinking Water on the E. coli Population in the Chicken Gut
Among intestinal coliform microbes in the broiler gut, there are potentially pathogenic Escherichia (E.) coli that can cause avian colibacillosis. The treatment with antibiotics favors the selection of multidrug-resistant bacteria and an alternative to ...
Sophie Kittler +11 more
doaj +1 more source
Eco-Evolutionary Effects of Bacterial Cooperation on Phage Therapy: An Unknown Risk?
If there is something we have learned from the antibiotic era, it is that indiscriminate use of a therapeutic agent without a clear understanding of its long-term evolutionary impact can have enormous health repercussions.
Adrián Cazares +4 more
doaj +1 more source
Antibiotic resistance genes (ARGs) are undergoing a remarkably rapid geographic expansion in various ecosystems, including pristine environments such as Antarctica.
Andrés Santos +3 more
doaj +1 more source
Bacteriophage therapy: back to the future [PDF]
In connection with growing problem of antimicrobial resistance, the search for alternative treatments for infection is popular topic nowadays. This article represents an overview of published data on the therapeutic use of bacteriophages, specifically in
Perepanova T.S. +3 more
doaj +1 more source
Since time immemorial, phages—the viral parasites of bacteria—have been protecting Earth’s biosphere against bacterial overgrowth. Today, phages could help address the antibiotic resistance crisis that affects all of society. The greatest hurdle to the introduction of phage therapy in Western medicine is the lack of an appropriate legal and regulatory ...
Jean-Paul Pirnay +6 more
openaire +3 more sources
Phage therapy refers to the use of bacteriophages (phages - bacterial viruses) as therapeutic agents against infectious bacterial diseases. This therapeutic approach emerged in the beginning of the 20th century but was progressively replaced by the use of antibiotics in most parts of the world after the second world war.
Joana Azeredo +6 more
openaire +2 more sources

