Results 21 to 30 of about 74,832 (169)

iProm-phage: A two-layer model to identify phage promoters and their types using a convolutional neural network

open access: yesFrontiers in Microbiology, 2022
The increased interest in phages as antibacterial agents has resulted in a rise in the number of sequenced phage genomes, necessitating the development of user-friendly bioinformatics tools for genome annotation. A promoter is a DNA sequence that is used
Muhammad Shujaat   +4 more
doaj   +1 more source

Phage on the stage [PDF]

open access: yesBacteriophage, 2015
The resurgence of interest in bacteriophages for use in combating antibiotic resistant bacteria is coincident with an urgent call for more effective science education practices, including hands-on learning opportunities. To address this issue, a number of solutions have been proposed, including a large educational experiment, begun in 2007 by the ...
Louise, Temple, Lynn, Lewis
openaire   +2 more sources

Genomic Analysis of Molecular Bacterial Mechanisms of Resistance to Phage Infection

open access: yesFrontiers in Microbiology, 2022
To optimize phage therapy, we need to understand how bacteria evolve against phage attacks. One of the main problems of phage therapy is the appearance of bacterial resistance variants.
Antón Ambroa   +19 more
doaj   +1 more source

Phages in nature [PDF]

open access: yesBacteriophage, 2011
Bacteriophages or phages are the most abundant organisms in the biosphere and they are a ubiquitous feature of prokaryotic existence. A bacteriophage is a virus which infects a bacterium. Archaea are also infected by viruses, whether these should be referred to as 'phages' is debatable, but they are included as such in the scope this article.
Clokie, MR   +3 more
openaire   +3 more sources

Recent Advances in Non-Conventional Antimicrobial Approaches for Chronic Wound Biofilms: Have We Found the ‘Chink in the Armor’?

open access: yesBiomedicines, 2019
Chronic wounds are a major healthcare burden, with huge public health and economic impact. Microbial infections are the single most important cause of chronic, non-healing wounds.
Snehal Kadam   +3 more
doaj   +1 more source

Phage Cocktails and the Future of Phage Therapy

open access: yesFuture Microbiology, 2013
Viruses of bacteria, known as bacteriophages or phages, were discovered nearly 100 years ago. Their potential as antibacterial agents was appreciated almost immediately, with the first 'phage therapy' trials predating Fleming's discovery of penicillin by approximately a decade.
Benjamin K, Chan   +2 more
openaire   +2 more sources

Phascinating Phages

open access: yesMicroorganisms, 2022
Treatment of infections caused by bacteria has become more complex due to the increasing number of bacterial strains that are resistant to conventional antimicrobial therapy. A highly promising alternative appears to be bacteriophage (phage) therapy, in which natural predators of bacteria, bacteriophages, play a role.
Marek Straka   +2 more
openaire   +3 more sources

Recent Advances in Shiga Toxin-Producing Escherichia coli Research in Latin America

open access: yesMicroorganisms, 2018
Pathogenic Escherichia coli are known to be a common cause of diarrheal disease and a frequently occurring bacterial infection in children and adults in Latin America. Despite the effort to combat diarrheal infections, the south of the American continent
Alfredo G. Torres   +6 more
doaj   +1 more source

First European Erwinia amylovora Lytic Bacteriophage Cocktails Effective in the Host: Characterization and Prospects for Fire Blight Biocontrol

open access: yesBiology
Fire blight, caused by the plant-pathogenic bacterium Erwinia amylovora, is a highly contagious and difficult-to-control disease due to its efficient dissemination and survival and the scarcity of effective control methods. Copper and antibiotics are the
Elena G. Biosca   +6 more
doaj   +1 more source

The short cytoplasmic region of phage T4 holin is essential for the transition from impermeable membrane protein complexes to permeable pores

open access: yesFrontiers in Microbiology
Virulent as well as temperate phages usually require lysis of bacteria to release their progeny into the surrounding. Double-stranded DNA phages achieve lysis by phage-encoded endolysins that degrade the bacterial cell wall.
Jan Michel Frederik Schwarzkopf   +5 more
doaj   +1 more source

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