Results 41 to 50 of about 129,184 (245)

Mechanisms and roles of phagocytosis in Drosophila and Caenorhabditis elegans [PDF]

open access: yesInvertebrate Survival Journal, 2007
Our understanding of the humoral immune response in both vertebrates and invertebrates has dramatically deepened in the past decade. In contrast, many of the mechanisms and roles of the cellular immune response remain to be elucidated. Phagocytosis is at
Y Nakanishi, A Shiratsuchi
doaj  

Diversity and Versatility of Phagocytosis: Roles in Innate Immunity, Tissue Remodeling, and Homeostasis

open access: yesFrontiers in Cellular and Infection Microbiology, 2017
Phagocytosis, a critical early event in the microbicidal response of neutrophils, is now appreciated to serve multiple functions in a variety of cell types. Professional phagocytes play a central role in innate immunity by eliminating pathogenic bacteria,
Justin J. Lim   +4 more
doaj   +1 more source

Phage-Phagocyte Interactions and Their Implications for Phage Application as Therapeutics

open access: yesViruses, 2017
Phagocytes are the main component of innate immunity. They remove pathogens and particles from organisms using their bactericidal tools in the form of both reactive oxygen species and degrading enzymes—contained in granules—that are potentially toxic ...
E. Jończyk-Matysiak   +6 more
semanticscholar   +1 more source

Staphylococcus aureus Multiplexes Death-Effector Deoxyribonucleosides to Neutralize Phagocytes

open access: yesFrontiers in Immunology, 2022
Adenosine synthase A (AdsA) is a key virulence factor of Staphylococcus aureus, a dangerous microbe that causes fatal diseases in humans. Together with staphylococcal nuclease, AdsA generates deoxyadenosine (dAdo) from neutrophil extracellular DNA traps ...
Eshraq Tantawy   +10 more
doaj   +1 more source

The Application of Organotypic Brain Slice Culture to Study Microglial Differentiation by Lycopersicon esculentum and Sambucus nigra Lectin Histochemistry [PDF]

open access: yesJournal of Cell and Molecular Research, 2014
Microglia cells are a subset of central nervous system (CNS) macrophages. Changes in the CNS such as injury, or developmental events, follow by morphological and physiological changes in microglia cells.
Roya Lari, Peter Kitchener
doaj   +1 more source

“Stimulate the Phagocyte”: Contested Terrains and the Birth of Cellular Immunity in turn-of-the-century Paris

open access: yesArts et Savoirs, 2022
This article traces the imaginative and linguistic work at play in the history of immunity from late nineteenth to early twentieth century France, culminating with Elie Metchnikoff, the “father” of immunology, and his discovery, the phagocyte ...
Loren K. Wolfe
doaj   +1 more source

Organotypic brain slice culture promotes the transformation of haemopoietic [PDF]

open access: yesJournal of Cell and Molecular Research, 2012
The exact developmental origin of microglia is still under debate. In the present study we investigated which heamatopoietic tissues and which features of the organotypic brain slice culture promoted microglia ramification. The potential of cells derived
Roya Lari   +2 more
doaj   +1 more source

Eros is a novel transmembrane protein that controls the phagocyte respiratory burst and is essential for innate immunity

open access: yesJournal of Experimental Medicine, 2017
The phagocyte respiratory burst is crucial for innate immunity. The transfer of electrons to oxygen is mediated by a membrane-bound heterodimer, comprising gp91phox and p22phox subunits. Deficiency of either subunit leads to severe immunodeficiency.
D. Thomas   +26 more
semanticscholar   +1 more source

Re-circulating Phagocytes Loaded with CNS Debris: A Potential Marker of Neurodegeneration in Parkinsons Disease?

open access: yesAIMS Medical Science, 2015
Diagnosis and monitoring of diseases by measurement of biochemical markers has most commonly been performed on samples of peripheral blood. However, no such markers are available for clinical use in the major diseases of the central nervous system (CNS).
Vanessa J. White, Ramesh C. Nayak
doaj   +1 more source

Emerging Evasion Mechanisms of Macrophage Defenses by Pathogenic Bacteria

open access: yesFrontiers in Cellular and Infection Microbiology, 2020
Macrophages participate to the first line of defense against infectious agents. Microbial pathogens evolved sophisticated mechanisms to escape macrophage killing.
Clarisse Leseigneur   +8 more
doaj   +1 more source

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