Results 41 to 50 of about 129,184 (245)
Mechanisms and roles of phagocytosis in Drosophila and Caenorhabditis elegans [PDF]
Our understanding of the humoral immune response in both vertebrates and invertebrates has dramatically deepened in the past decade. In contrast, many of the mechanisms and roles of the cellular immune response remain to be elucidated. Phagocytosis is at
Y Nakanishi, A Shiratsuchi
doaj
Phagocytosis, a critical early event in the microbicidal response of neutrophils, is now appreciated to serve multiple functions in a variety of cell types. Professional phagocytes play a central role in innate immunity by eliminating pathogenic bacteria,
Justin J. Lim +4 more
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Phage-Phagocyte Interactions and Their Implications for Phage Application as Therapeutics
Phagocytes are the main component of innate immunity. They remove pathogens and particles from organisms using their bactericidal tools in the form of both reactive oxygen species and degrading enzymes—contained in granules—that are potentially toxic ...
E. Jończyk-Matysiak +6 more
semanticscholar +1 more source
Staphylococcus aureus Multiplexes Death-Effector Deoxyribonucleosides to Neutralize Phagocytes
Adenosine synthase A (AdsA) is a key virulence factor of Staphylococcus aureus, a dangerous microbe that causes fatal diseases in humans. Together with staphylococcal nuclease, AdsA generates deoxyadenosine (dAdo) from neutrophil extracellular DNA traps ...
Eshraq Tantawy +10 more
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The Application of Organotypic Brain Slice Culture to Study Microglial Differentiation by Lycopersicon esculentum and Sambucus nigra Lectin Histochemistry [PDF]
Microglia cells are a subset of central nervous system (CNS) macrophages. Changes in the CNS such as injury, or developmental events, follow by morphological and physiological changes in microglia cells.
Roya Lari, Peter Kitchener
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This article traces the imaginative and linguistic work at play in the history of immunity from late nineteenth to early twentieth century France, culminating with Elie Metchnikoff, the “father” of immunology, and his discovery, the phagocyte ...
Loren K. Wolfe
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Organotypic brain slice culture promotes the transformation of haemopoietic [PDF]
The exact developmental origin of microglia is still under debate. In the present study we investigated which heamatopoietic tissues and which features of the organotypic brain slice culture promoted microglia ramification. The potential of cells derived
Roya Lari +2 more
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The phagocyte respiratory burst is crucial for innate immunity. The transfer of electrons to oxygen is mediated by a membrane-bound heterodimer, comprising gp91phox and p22phox subunits. Deficiency of either subunit leads to severe immunodeficiency.
D. Thomas +26 more
semanticscholar +1 more source
Diagnosis and monitoring of diseases by measurement of biochemical markers has most commonly been performed on samples of peripheral blood. However, no such markers are available for clinical use in the major diseases of the central nervous system (CNS).
Vanessa J. White, Ramesh C. Nayak
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Emerging Evasion Mechanisms of Macrophage Defenses by Pathogenic Bacteria
Macrophages participate to the first line of defense against infectious agents. Microbial pathogens evolved sophisticated mechanisms to escape macrophage killing.
Clarisse Leseigneur +8 more
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