Results 21 to 30 of about 138,964 (211)

RNA interference screening reveals host CaMK4 as a regulator of cryptococcal uptake and pathogenesis [PDF]

, 2017
Cryptococcus neoformans , the causative agent of cryptococcosis, is an opportunistic fungal pathogen that kills over 200,000 individuals annually. This yeast may grow freely in body fluids, but it also flourishes within host cells.
Doering, Tamara L, Hole, Camaron R, Khader, Shabaana A, Srikanta, Deepa, Williams, Matthew   +4 more
core   +2 more sources

Liberação de peróxido de hidrogênio por fagócitos de glândulas mamárias bovinas hígidas e infectadas Hydrogen peroxide release by phagocytes from healthy and infected bovine mammary gland

Ciência Rural, 2012
O objetivo do presente estudo foi avaliar a capacidade de liberação de peróxido de hidrogênio (H2O2) por fagócitos oriundos de glândulas mamárias bovinas sadias e infectadas.
Fernanda Alves Brasil, Milton Ricardo Azedo, Sandra Satiko Kitamura, Maiara Garcia Blagitz, Fernando Nogueira de Souza, Alice Maria Melville Paiva Della Libera   +5 more
doaj   +1 more source

Dangerous Liaisons: Interactions of Cryptococcus neoformans with Host Phagocytes

Pathogens, 2020
Cryptococcus neoformans is an opportunistic fungal pathogen and a leading cause of death in immunocompromised individuals. The interactions of this yeast with host phagocytes are critical to disease outcome, and C. neoformans is equipped with an array of
Elizabeth A. Gaylord, Hau Lam Choy, Tamara L. Doering   +2 more
doaj   +1 more source

Immunological mechanisms involved in macrophage activation and polarization in schistosomiasis

Parasitology, 2023
Human schistosomiasis is caused by helminths of the genus Schistosoma. Macrophages play a crucial role in the immune regulation of this disease. These cells acquire different phenotypes depending on the type of stimulus they receive.
Irlla Correia Lima Licá, Gleycka Cristine Carvalho Gomes Frazão, Ranielly Araujo Nogueira, Maria Gabriela Sampaio Lira, Vitor Augusto Ferreira dos Santos, João Gustavo Mendes Rodrigues, Guilherme Silva Miranda, Rafael Cardoso Carvalho, Lucilene Amorim Silva, Rosane Nassar Meireles Guerra, Flávia Raquel Fernandes Nascimento   +10 more
doaj   +1 more source

Mycobacterium abscessus Opsonization Allows an Escape from the Defensin Bactericidal Action in Drosophila

Microbiology Spectrum, 2023
Mycobacterium abscessus, an intracellular nontuberculous mycobacterium, is considered the most pathogenic species among the group of rapidly growing mycobacteria. The resistance of M. abscessus to the host innate response contributes to its pathogenicity
Hamadoun Touré, Nicolas Durand, Isabelle Guénal, Jean-Louis Herrmann, Fabienne Girard-Misguich, Sébastien Szuplewski   +5 more
doaj   +1 more source

Phagocyte Transcriptomic Analysis Reveals Focal Adhesion Kinase (FAK) and Heparan Sulfate Proteoglycans (HSPGs) as Major Regulators in Anti-bacterial Defense of Crassostrea hongkongensis

Frontiers in Immunology, 2020
Invertebrates generally lack adaptive immunity and compensate for this with highly efficient innate immune machineries such as phagocytosis by hemocytes to eradicate invading pathogens.
Yue Lin, Yue Lin, Fan Mao, Fan Mao, Fan Mao, Nai-Kei Wong, Xiangyu Zhang, Xiangyu Zhang, Kunna Liu, Kunna Liu, Minwei Huang, Minwei Huang, Minwei Huang, Haitao Ma, Haitao Ma, Haitao Ma, Zhiming Xiang, Zhiming Xiang, Zhiming Xiang, Jun Li, Jun Li, Jun Li, Shu Xiao, Shu Xiao, Shu Xiao, Yang Zhang, Yang Zhang, Yang Zhang, Ziniu Yu, Ziniu Yu, Ziniu Yu   +30 more
doaj   +1 more source

The emerging roles of long non-coding RNA in host immune response and intracellular bacterial infections

Frontiers in Cellular and Infection Microbiology, 2023
The long non-coding RNAs (lncRNAs) are evolutionarily conserved classes of non-coding regulatory transcripts of > 200 nucleotides in length. They modulate several transcriptional and post-transcriptional events in the organism.
Aryashree Arunima, Erin J. van Schaik, James E. Samuel   +2 more
doaj   +1 more source

The Diverse Roles of the Global Transcriptional Regulator PhoP in the Lifecycle of Yersinia pestis

Pathogens, 2020
Yersinia pestis, the causative agent of plague, has a complex infectious cycle that alternates between mammalian hosts (rodents and humans) and insect vectors (fleas). Consequently, it must adapt to a wide range of host environments to achieve successful
Hana S. Fukuto, Gloria I. Viboud, Viveka Vadyvaloo   +2 more
doaj   +1 more source

Vomocytosis: Too Much Booze, Base, or Calcium? [PDF]

, 2019
Macrophages are well known for their phagocytic activity and their role in innate immune responses. Macrophages eat non-self particles, via a variety of mechanisms, and typically break down internalized cargo into small macromolecules.
Aaron, Alvarez, Alvarez, Artavanis-Tsakonas, Bain, Ben-Abdallah, Bielska, Blackstock, Boya, Bryan, Burch, Chang, Charlier, Chen, Cheng, Chu, Circu, Cox, Davis, De Leon-Rodriguez, De Leon-Rodriguez, Denham, Di, Diamond, Doshi, Dragotakes, Drew, Erb-Downward, Erwig, Evans, Feldmesser, Franchi, Fu, Gilbert, Gordon, Guerra, Gustafson, Haka, Han, Henson, Heo, Hibbs, Hoag, Hommel, Huang, Hybiske, Iwasaki, Johnston, Kjos, Kleinschek, Kruskal, Kusner, Lei, Leopold Wager, Levitz, Levitz, Lim, Liu, Lévêque, Ma, Maderna, May, Milam, Mosser, Murdock, Murray, Myers, Müller, Nel, Nicola, Nunes, Okagaki, O’Meara, Pauwels, Qiu, Rajasingham, Russell, Samantaray, Santiago-Tirado, Singh, Smith, Stukes, Stukes, Swisher, Tucker, Vashi, Voelz, Vu, Vu, Walkey, Wang, Wang, Watkins, Weiss, Wormley, Wozniak, Yates, Yoshida, Zaragoza   +98 more
core   +2 more sources

MICROEMULSION OF BRAZIL NUT OIL AS A NATURAL PRODUCT TO IMPROVE SUPEROXIDE RELEASE IN HUMAN PHAGOCYTES

Química Nova
The aim of this study was to develop and characterize a Brazil nut oil microemulsion system and determine the effect of this microemulsion on the superoxide release in human phagocytes.
Karol Patel Fiori, Maycon de Paula Ribeiro Torres, Jessica Iara Schons, Elton Brito Ribeiro, Roberta Martins Nogueira, Leonardo G. Vasconcelos, Carla R. Andrighetti, Marcos José Jacinto, Denia M. de S. Valladão   +8 more
doaj   +1 more source