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Roles of the phagocytosis checkpoint in radiotherapy [PDF]

open access: yesCell Death and Disease
Radiotherapy is widely used in cancer treatment in both curative and palliative care due to its good safety profile and broad clinical availability.
Yulan Kui   +4 more
doaj   +2 more sources

Evaluating antibody mediated opsonophagocytosis of bacteria via lab protocol: RAW 264.7 cell phagocytosis assay. [PDF]

open access: yesPLoS ONE
Assessing the phagocytosis of microbes by macrophages is an important component of studies of novel immunotherapeutics, antimicrobial drugs, immune effectors, or any immunology related research.
Matthew Slarve   +5 more
doaj   +2 more sources

Ganoderma lucidum spore oil alleviates psychological stress-evoked tumor progression by enhancing FcγR-mediated macrophage phagocytosis [PDF]

open access: yesChinese Medicine
Background Ganoderma lucidum (G. lucidum), has been documented as a medicinal herb in classical texts and officially recognized in both Eastern and Western pharmacopeias. G.
Dong-Dong Li   +19 more
doaj   +2 more sources

Royal jelly fermented by honeybee queen (Apis mellifera)-derived Lactobacillus panisapium M1 enhances macrophage phagocytosis through the TLR2/MAPK/SR signaling pathway [PDF]

open access: yesBMC Complementary Medicine and Therapies
Background Royal jelly (RJ) has traditionally been used to maintain health, and its fatty acids (10-hydroxy decanoic acid and 10-hydroxy-2-decenoic acid) are reported to have immunomodulatory effects.
Shuhei Nonobe   +5 more
doaj   +2 more sources

Succinate Promotes Phagocytosis of Monocytes/Macrophages in Teleost Fish

open access: yesFrontiers in Molecular Biosciences, 2021
Development of immunity-based strategy to manage bacterial infection is urgently needed in aquaculture due to the widespread of antibiotic-resistant bacteria.
Dai-xiao Yang   +15 more
doaj   +1 more source

Regulators of phagocytosis as pharmacologic targets for stroke treatment

open access: yesFrontiers in Pharmacology, 2023
Stroke, including ischemic and hemorrhagic stroke, causes massive cell death in the brain, which is followed by secondary inflammatory injury initiated by disease-associated molecular patterns released from dead cells. Phagocytosis, a cellular process of
Jian Cheng   +6 more
doaj   +1 more source

Inflammatory macrophages exploit unconventional pro-phagocytic integrins for phagocytosis and anti-tumor immunity

open access: yesCell Reports, 2021
Summary: Blockade of the inhibitory checkpoint SIRPα-CD47 promotes phagocytosis of cancer cells by macrophages and is a promising avenue in anti-cancer therapy.
Zhenghai Tang   +6 more
doaj   +1 more source

In vitro analysis of anti-HPA-1a dependent platelet phagocytosis and its inhibition using a new whole blood phagocytosis assay (WHOPPA)

open access: yesFrontiers in Immunology, 2023
Fetal and neonatal alloimmune thrombocytopenia (FNAIT) is a serious bleeding condition mostly caused by the reaction between maternal anti-HPA-1a antibodies and fetal platelets. This reaction leads to Fc-dependent platelet phagocytosis.
Paula Ames   +11 more
doaj   +1 more source

A genome-wide CRISPR/Cas9 screen to identify phagocytosis modulators in monocytic THP-1 cells

open access: yesScientific Reports, 2021
Phagocytosis of microbial pathogens, dying or dead cells, and cell debris is essential to maintain tissue homeostasis. Impairment of these processes is associated with autoimmunity, developmental defects and toxic protein accumulation.
Benjamin Lindner   +6 more
doaj   +1 more source

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