The role of endogenous annexin A1 on leukocyte biology [PDF]
PhDInflammation is the body's innate immune response to the damage caused to its cells and vascularised tissue, either by injury or microbial pathogens.
Yona, Simon
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The Roles of Membrane Rafts in CD32A-Mediated Phagocytosis [PDF]
Membrane rafts are highly dynamic heterogeneous sterol- and sphingolipid-rich micro-domains on cell surfaces. They are generally believed to provide residency for cell surface molecules (e.g., adhesion and signaling molecules) and scaffolding to ...
Periasamy Selvaraj +2 more
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Phagocytic properties of lung alveolar wall cells [PDF]
For the purpose to define the mechanism of heavy metal intoxication by inhalation, morphologic observations were made on rat lungs after nasal instillation of iron colloid particles of positive and negative electric charges. Histochemical observation was
Tanaka, Akisuke
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Phagocytosis: Molecular Mechanisms and Physiological Implications
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject.
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Phagocytosis of aged human neutrophils by macrophages is mediated by a novel "charge-sensitive" recognition mechanism [PDF]
The removal of neutrophils and their histotoxic contents from the inflamed site is a prerequisite for resolution of tissue injury, and a point at which factors critical to the pathogenesis of chronic inflammation may act.
Savill, John S +5 more
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Phagocytosis, as an innate immune defense mechanism, is the first process to respond to pathogens. It is also one of the initiating branches of an adaptive immune response.
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Priming by recombinant chicken interleukin-2 induces selective expression of IL-8 and IL-18 mRNA in chicken heterophils during receptor-mediated phagocytosis of opsonized and nonopsonized Salmonella enterica serovar enteritidis [PDF]
Heterophils, the principal avian polymorphonuclear leukocytes (PMNs) equivalent to the mammalian neutrophil, function as professional phagocytes against bacterial infections, mediate acute inflammation, and respond to cytokine stimulation to aid in ...
Michael H Kogut +5 more
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Contribution of receptors to 'Neisseria meningitidis' interactions with human macrophages [PDF]
N. meningitidis is a gram-negative human pathogen that invades human cells, evades immune responses and goes on to cause meningococcal disease, sepsis and death.
Abdillahi, Fatumo Abdi
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A hierarchical role for classical pathway complement proteins in the clearance of apoptotic cells in vivo [PDF]
The strongest susceptibility genes for the development of systemic lupus erythematosus (SLE) in humans are null mutants of classical pathway complement proteins. There is a hierarchy of disease susceptibility and severity according to the position of the
H. Terence Cook +29 more
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RNA interference in J774 macrophages reveals a role for coronin 1 in mycobacterial trafficking but not in actin-dependent processes [PDF]
Macrophages are crucial for innate immunity, apoptosis, and tissue remodeling, processes that rely on the capacity of macrophages to internalize and process cargo through phagocytosis.
Pieters, J. +5 more
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