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An assessment of machine learning methods to quantify blood lactate from neutrophils phagocytic activity [PDF]
Scientific ReportsPhagocytosis is a critical component of innate immunity that helps the body defend itself against infection, foreign particles, and cellular debris. Investigating and quantifying phagocytosis can help understand how the immune system identifies foreign ...
Muhammad Nabeel Tahir +2 more
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A crosstalk between adhesion and phagocytosis integrates macrophage functions into their microenvironment [PDF]
iScienceSummary: Phagocytosis is the process of actin-dependent internalization and degradation of large particles. Macrophages, which are professional phagocytes, are present in all tissues and are, thus, exposed to environments with different mechanical ...
Manon Depierre +5 more
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Current Biology, 2011 SummaryPhagocytosis is defined as the receptor-mediated engulfment of large (≥0.5 μm) particles into plasma membrane-derived vacuoles called phagosomes. Following scission from the plasma membrane, the phagosomes undergo a maturation process, sequentially fusing with endosomes and lysosomes, ultimately becoming phagolysosomes — highly acidic and ...
Botelho, Roberto J., Grinstein, Sergio
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A transient inflammatory response contributes to oxaliplatin neurotoxicity in mice
Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1985-1998, December 2022., 2022 Abstract Objectives Peripheral neuropathy is a relevant dose‐limiting adverse event that can affect up to 90% of oncologic patients with colorectal cancer receiving oxaliplatin treatment. The severity of neurotoxicity often leads to dose reduction or even premature cessation of chemotherapy.
Aina Calls +9 more
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Frontiers in Microbiology, 2022 Macrophages play a central role in the innate immune response to respiratory viral infections through pro-inflammatory factor secretion and phagocytosis.
Naoko Morita +6 more
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Frontiers in Immunology, 2023 Fetal and neonatal alloimmune thrombocytopenia (FNAIT) is a serious bleeding condition mostly caused by the reaction between maternal anti-HPA-1a antibodies and fetal platelets. This reaction leads to Fc-dependent platelet phagocytosis.
Paula Ames +11 more
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Succinate Promotes Phagocytosis of Monocytes/Macrophages in Teleost Fish
Frontiers in Molecular Biosciences, 2021 Development of immunity-based strategy to manage bacterial infection is urgently needed in aquaculture due to the widespread of antibiotic-resistant bacteria.
Dai-xiao Yang +15 more
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