Results 141 to 150 of about 50,774 (237)
Phagocytosis of yeast activates recruitment of proteases and trafficking factors from the secretory and endosomal pathways to the IRAP compartment and subsequently phagosomes, promoting cross‐presentation. In the absence of Sec22b, IRAP endosome and phagosome maturation to late endosomes is accelerated.
Alice Senni +7 more
wiley +1 more source
Advances in the Role of Adipose Tissue in Promoting Injury Repair and Resist Infection
ABSTRACT Background In recent years, adipose tissue (AT) transplantation has increasingly been noticed by many people in the field of tissue repair and regeneration. Accumulating evidence demonstrates that AT exerts dual functions in promoting tissue repair and conferring anti‐infective properties, with distinct biological effects attributed to its ...
Xi Duan +4 more
wiley +1 more source
![Figure][1] Phagosomes formed via the CR3 receptor assemble an actin comet tail (arrow, left), whereas FcgR phagosomes do not (right). Bohdanowicz et al. describe how different phosphatidylinositol phosphates (PIPs) promote actin polymerization on specific phagosome membranes to move ...
openaire +2 more sources
ABSTRACT Background Gestational diabetes mellitus (GDM), a common pregnancy complication characterized by maternal hyperglycemia, negatively impacts offspring health. Skeletal muscle, a critical tissue for glucose and lipid metabolism, is especially vulnerable to prenatal environmental insults.
Rui Liu +7 more
wiley +1 more source
ABSTRACT Background Sarcopenic obesity, where excess body fat coexists with reduced muscle mass and function, is becoming increasingly common in ageing populations and contributes to poor physical and metabolic health. Although adipose tissue–secreted factors are implicated in muscle decline, the specific mechanisms remain unclear.
Joshua M. J. Price +8 more
wiley +1 more source
Phagocytosis of Legionella pneumophila is mediated by human monocyte complement receptors. [PDF]
We have examined receptors mediating phagocytosis of the intracellular bacterial pathogen, Legionella pneumophila. Three mAbs against the type 3 complement receptor (CR3), which recognizes C3bi, inhibit adherence of L.
Horwitz, MA, Payne, NR
core
Chronic Granulomatous Disease: Clinical and Molecular Characterization of Brazilian Patients
Chronic granulomatous disease is a rare inborn error of immunity characterized by the deficient production of reactive oxygen species in phagocytes, which are used in pathogen elimination. Affected individuals become susceptible to severe infections.
Leonardo Martinello da Rosa +4 more
wiley +1 more source
Transcriptional Adaptations to Muscle Loading in a Murine Model of Achilles Tendinopathy
ABSTRACT Achilles tendinopathy limits mobility and decreases quality of life. Physical therapy (eccentric muscle loading) improves tendon function; however, the underlying mechanisms are unknown. This study investigated the effect of load magnitude and treatment duration in a mouse Achilles tendinopathy model.
Dylan C. Easley +5 more
wiley +1 more source
This study reports a septic shock case in inland China caused by coinfection of Shewanella algae bloodstream infection and Epstein‐Barr virus. Genomic analysis revealed freshwater adaptation of the strain via unique genes for transporters and carbohydrate‐active enzymes.
Jianmei Chen +6 more
wiley +1 more source

