Results 121 to 130 of about 22,892 (257)
Combining clinical data with serum proteomics and metabolomics, the HGB–CAPZB–acetic acid model was developed as a potential diagnostic index to distinguish the active and stable stages of Helicobacter pylori‐infected chronic gastritis, and the related mechanism was explored through multi‐omics.
Tiantong Jiang +7 more
wiley +1 more source
pH measurement on isolated phagosomes. [PDF]
Intra-vesicular pH of phagosomes containing FITC-labeled zymosan was determined in untreated control preparations (left panel), untreated preparations from Stat1−/− BMMs (middle panel), and control preparations treated with 93 mM K2SO4 (right panel ...
Stephen M. Beverley (174720) +3 more
core +1 more source
ABSTRACT The instability of atherosclerotic plaques, particularly intraplaque hemorrhage (IPH), drives life‐threatening cardiovascular events, a process in which vascular smooth muscle cell (VSMC)‐derived foam cells play a significant role. We aim to identify key biomarkers associated with VSMC‐derived foam cells and IPH by analyzing data from human ...
Ling‐Lin Qian +4 more
wiley +1 more source
A Drosophila Model to Image Phagosome Maturation
Phagocytosis involves the internalization of extracellular material by invagination of the plasma membrane to form intracellular vesicles called phagosomes, which have functions that include pathogen degradation.
Douglas A. Brooks +3 more
doaj +1 more source
This review summarizes the recent progress in responsive NO‐releasing materials and their applications in biofilm‐associated infectious diseases. The design principles and response mechanisms are given to provide inspiration toward the future development of multi‐responsive NO‐releasing materials.
Wenyue Sun +8 more
wiley +1 more source
STIM1 Juxtaposes ER to Phagosomes, Generating Ca2+ Hotspots that Boost Phagocytosis [PDF]
SummaryBackgroundEndoplasmic reticulum (ER) membranes are recruited to phagosomes, but the mechanism and functional significance of this ER recruitment is not known.
Hasler, Udo +7 more
core +1 more source
Nanomaterials' Multigenerational Effects by Single and Joint Exposure in Non‐mammalian Models
ABSTRACT Nanotoxicology has mainly focused on single‐generation studies, leaving multigenerational toxicity underexplored. Having animal welfare recently gained importance, we aimed to provide the state‐of‐the‐art of knowledge about multigenerational effects in non‐mammalian models in the case of nanomaterials (NM) single and joint exposure to other ...
Andy Joel Taipe Huisa +9 more
wiley +1 more source
Pancreatic cancer (PaCa) has a poor prognosis, with low resection rates and high relapse rates, highlighting the urgent need for novel diagnostic biomarkers. Here, we performed whole‐transcriptome sequencing of plasma‐derived exosomes from PaCa patients and identified several differentially expressed circular RNAs (circRNAs).
Xiaomeng He +10 more
wiley +1 more source
Pulses of Class I PI3kinase activity identify the release and recapture of prey from neutrophil phagosomes [PDF]
Class I PI3kinases coordinate the delivery of microbicidal effectors to the phagosome by forming the phosphoinositide lipid second messenger, phosphatidylinositol (3, 4, 5)-trisphosphate (PIP3).
Ellett, Felix E. +13 more
core +1 more source
Preparation of intact, highly purified phagosomes from Dictyostelium [PDF]
Phagocytosis plays a fundamental role in the immune system for the defense against invading microorganisms and the clearing of apoptotic and cancerous cells.
Soldati, Thierry +5 more
core +1 more source

