Chemical modification allows phallotoxins and amatoxins to be used as tools in cell biology [PDF]
Beilstein Journal of Organic Chemistry, 2012 Phallotoxins inhibit the dynamics of microfilaments in cells and lead to apoptosis. Due to poor cellular uptake these effects cannot be studied in live cells, even at millimolar toxin concentrations, nor can phalloidin be used for the elimination of ...
Hartmut Echner, Jan Anderl
exaly +5 more sources
An Automated and Highly Sensitive Chemiluminescence Immunoassay for Diagnosing Mushroom Poisoning [PDF]
Frontiers in Chemistry, 2021 Mushrooms containing Amanita peptide toxins are the major cause of mushroom poisoning, and lead to approximately 90% of deaths. Phallotoxins are the fastest toxin causing poisoning among Amanita peptide toxins.
Jianyu Zhu +8 more
doaj +2 more sources
Exploring fungal RiPPs from the perspective of chemical ecology [PDF]
Fungal Biology and Biotechnology, 2022 Since the initial detection, in 2007, of fungal ribosomally synthesised and post-translationally modified peptides (RiPPs), this group of natural products has undergone rapid expansion, with four separate classes now recognised: amatoxins/phallotoxins ...
R. E. Ford, G. D. Foster, A. M. Bailey
doaj +2 more sources
Pseudosperma arenarium (Inocybaceae), a new poisonous species from Eurasia, based on morphological, ecological, molecular and biochemical evidence [PDF]
MycoKeys, 2022 In this study, Pseudosperma arenarium is proposed as a new species, based on morphological, ecological, molecular and biochemical evidence. The new species grows on sandy ground under Populus and Pinus sylvestris in north-western China and northern ...
Ya-Ya Yan +6 more
doaj +4 more sources
Amanita Section Phalloideae Species in the Mediterranean Basin: Destroying Angels Reviewed [PDF]
Biology, 2022 In Europe, amatoxin-containing mushrooms are responsible for most of the deadly poisonings caused by macrofungi. The present work presents a multidisciplinary revision of the European species of Amanita sect.
Pablo Alvarado +10 more
doaj +2 more sources
A New Muscarine-Containing Inosperma (Inocybaceae, Agaricales) Species Discovered From One Poisoning Incident Occurring in Tropical China [PDF]
Frontiers in Microbiology, 2022 Currently, mushroom poisoning still poses a huge problem to humans' health and life globally. Poisoning incidents caused by Inosperma spp. were reported continuously in tropical China in recent years.
Lun-Sha Deng +7 more
doaj +2 more sources
Toxin Profiling of Amanita citrina and A. sinocitrina: First Report of Buiotenine Detection [PDF]
ToxinsAmanita species are widely distributed worldwide. Many of these species are poisonous and can cause health problems, resulting in morbidity and mortality.
Yi-Zhe Zhang +7 more
doaj +2 more sources
Chemical reactivity and bioactivity properties of the Phallotoxin family of fungal peptides based on Conceptual Peptidology and DFT study [PDF]
Heliyon, 2019 A methodology based on the concepts that arise from Density Functional Theory (CDFT) was chosen for the calculation of the global and local reactivity descriptors of the Phallotoxin family of fungal peptides. The determination of the active sites for the
Norma Flores-Holguín +2 more
doaj +2 more sources
Molecular Phylogeny and Morphology Reveal Four New Species of Conocybe (Bolbitiaceae, Agaricales) from the Qinghai-Xizang Plateau, China [PDF]
Journal of FungiThe Qinghai-Xizang Plateau, known for its high altitude, geological history of plate collision, crustal uplift, and special ecology factors, provides an ideal environment for studying fungal biodiversity in extreme environmental conditions.
Xi-Xi Han +8 more
doaj +2 more sources
Mixed toxin profiles in two new and one known species of Inocybe (Inocybaceae) from northern China [PDF]
MycoKeysMushroom poisoning has become a serious food safety issue in China. Poisoning incidents caused by species of Inocybaceae have been continuously reported from tropical to temperate regions of China in recent years.
Jia-Qi Liang +9 more
doaj +4 more sources