Results 91 to 100 of about 666,519 (246)

Crystal nucleation in pharmaceutical cocrystals systems

, 2021
In this thesis the nucleation kinetics in three pharmaceutical cocrystal systems has been investigated through induction time experiments, identification of the nucleating solid phase and analysis of the nucleation data by the classical nucleation theory (CNT).
openaire   +1 more source

SOLID-STATE PROPERTIES AND SOLUBILITY STUDIES OF NOVEL PHARMACEUTICAL COCRYSTAL OF ITRACONAZOLE

International Journal of Applied Pharmaceutics, 2018
Objective: Pharmaceutical cocrystal is a promising method to improve the solubility of active pharmaceutical ingredients (APIs). Itraconazole (ITZ) is a BCS class II antifungal drug with poor aqueous solubility, therefore an attempt was made to improve ...
Stevanus Hiendrawan, Bambang Veriansyah, R. Tjandrawinata   +2 more
semanticscholar   +1 more source

Structure of mildronate, its pharmaceutical salts and cocrystals [PDF]

, 2011
Anatoly Mishnev, Ivars Kalviņš, L. Aleksejeva, Andrey N. Lebedev   +3 more
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Novel Pharmaceutical Cocrystals and Solvate Crystals of Nobiletin, a Citrus Flavonoid with Potent Pharmacological Activity

, 2023
Shota Tokunaga, Chie Uchikoshi, Kei Hayashi, Hironori Suzuki, Masataka Ito, Shuji Noguchi   +5 more
openalex   +2 more sources

Dissolution and Pharmacokinetic Studies of Paracetamol-4,4′-Bipyridine Cocrystals Obtained Using Four Methods

Crystals
Paracetamol-4,4′-bipyridine cocrystals were synthesized using a solution method, reflux method, grinding method, and ultrasonic method. The structures and properties were characterized through the utilization of single-crystal X-ray diffraction (SXRD ...
Xiaoming Zhang, Yejia Huang, Jinliang Li, Yiying Chen, Jialing Lian   +4 more
doaj   +1 more source

Pharmaceutical cocrystal-a deft technique for solubility enhancement

Pharmaceutical Sciences Asia, 2023
S. Bhattacharyya, A. Manjunath
semanticscholar   +1 more source

An Overview of Pharmaceutical Cocrystals as Intellectual Property [PDF]

Molecular Pharmaceutics, 2007
This review article focuses on the interaction among certain scientific, legal, and regulatory aspects of pharmaceutical crystal forms. The article offers an analysis of pharmaceutical cocrystals as patentable inventions by drawing upon recent scientific developments in the field. Several potential commercial advantages of pharmaceutical cocrystals are
openaire   +2 more sources

Pharmaceutical Cocrystals of Ethenzamide: Molecular Structure Analysis Based on Vibrational Spectra and DFT Calculations [PDF]

, 2022
Mei Wan, Jiyuan Fang, Jiadan Xue, Jianjun Liu, Jianyuan Qin, Zhi Hong, Jiu‐sheng Li, Yong Du   +7 more
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Data for: Amino acid based Pharmaceutical Cocrystals and Cocrystal Hydrates of the Chlorothiazide: Structural Studies and Physicochemical Properties

, 2020
Ying Bao
openalex   +1 more source

A Novel Cocrystal of Daidzein with Piperazine to Optimize the Solubility, Permeability and Bioavailability of Daidzein

Molecules
It is well known that daidzein has various significant medicinal values and health benefits, such as anti-oxidant, anti-inflammatory, anti-cancer, anti-diabetic, cholesterol lowering, neuroprotective, cardioprotective and so on.
Zhipeng Wang, Shuang Li, Qi Li, Wenwen Wang, Meiru Liu, Shiying Yang, Li Zhang, Dezhi Yang, Guanhua Du, Yang Lu   +9 more
doaj   +1 more source