Results 81 to 90 of about 2,679 (172)

A Novel Cocrystal of Daidzein with Piperazine to Optimize the Solubility, Permeability and Bioavailability of Daidzein

Molecules
It is well known that daidzein has various significant medicinal values and health benefits, such as anti-oxidant, anti-inflammatory, anti-cancer, anti-diabetic, cholesterol lowering, neuroprotective, cardioprotective and so on.
Zhipeng Wang, Shuang Li, Qi Li, Wenwen Wang, Meiru Liu, Shiying Yang, Li Zhang, Dezhi Yang, Guanhua Du, Yang Lu   +9 more
doaj   +1 more source

A Review on Pharmaceutical Cocrystals [PDF]

International Journal for Pharmaceutical Research Scholars, 2018
A. S. Athira, S. Anu, S. R. Seeja, M. S. Thaifa   +3 more
openaire   +1 more source

In Silico Coformer Screening for Mefenamic Acid Cocrystallization

Jurnal Info Kesehatan
Cocrystallization is a widely used approach to enhance the solubility and dissolution characteristics of poorly soluble drugs. A pharmaceutical cocrystal is a multicomponent system composed of a solid active pharmaceutical ingredient (API) and a coformer,
Aulia Fikri Hidayat, Taufik Muhammad Fakih, Gita Cahya Eka Darma, Ratu Choesrina   +3 more
doaj   +1 more source

Advances in Quantitative Analytical Methods for Solid Drugs

Crystals
The solid form of the drug can directly affect the physicochemical properties, bioavailability, safety, and efficacy of the drug, and its types mainly include amorphous state, single-component polycrystalline, hydrate, solvate, salt, and cocrystal ...
Yue Tao, Yuhan Gao, Baoxi Zhang, Kun Hu, Yifei Xie, Li Zhang, Shiying Yang, Yang Lu   +7 more
doaj   +1 more source

Ketoconazole-Fumaric Acid Pharmaceutical Cocrystal: From Formulation Design for Bioavailability Improvement to Biocompatibility Testing and Antifungal Efficacy Evaluation. [PDF]

Int J Mol Sci
Baldea I, Moldovan R, Nagy AL, Bolfa P, Decea R, Miclaus MO, Lung I, Gherman AMR, Sevastre-Berghian A, Martin FA, Kacso I, Răzniceanu V.   +11 more
europepmc   +1 more source

An Antibacterial "Drug-Drug" Cocrystal of Trimethoprim with Sulfathiazole Achieving Synchronized Dual-Drug Release and Pharmacokinetics. [PDF]

ACS Omega
Li WH, Sun XH, Chen X, Gao SH, Li FY, Mo H, Hu XY, Wang XK, Liu F.   +8 more
europepmc   +1 more source

The cocrystals of isorhamnetin and isoliquiritigenin with 4,4'-bipyridine: system characterization, stability, dissolution and anticancer activity. [PDF]

RSC Adv
Liu Y, Lei J, Li T, Zhong A, Zhu Z, Lu J, Wang Z, Zhao P, Wu Z.   +8 more
europepmc   +1 more source

Systematic Scale-Up of Mechanochemical Paracetamol-Oxalic Acid Cocrystal Synthesis across Multiple Milling Technologies. [PDF]

Org Process Res Dev
Schöbel JH, Gopinath D, Felderhoff M.
europepmc   +1 more source

Simultaneous quantification of drug and coformer during cocrystal dissolution using <i>in situ</i> UV spectroscopy and multicomponent analysis. [PDF]

ADMET DMPK
Ishida S, Lee S, Sinko B, Box K, Sugano K.   +4 more
europepmc   +1 more source

From Chemistry to Clinic: Amorphous Solid-State Modification Strategies for Oral Azole Antifungals. [PDF]

ACS Omega
Harakraj TJ, Witika BA, Aucamp ME, Poka MS.   +3 more
europepmc   +1 more source