Results 21 to 30 of about 666,519 (246)
Enhancing the Solubility of Ketoconazole via Pharmaceutical Cocrystal [PDF]
Journal of Physics: Conference Series, 2019 This present research is to synthesized and characterized cocrystal of ketoconazole through cocrystallization process in order to improve solubility properties of ketoconazole.
Indra Indra +2 more
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Influence of Coformer Stoichiometric Ratio on Pharmaceutical Cocrystal Dissolution: Three Cocrystals of Carbamazepine/4-Aminobenzoic Acid. [PDF]
Mol Pharm, 2016 Cocrystallization is a technique to optimize solid forms that shows great potential to improve the solubility of active pharmaceutical ingredients (APIs).
Li Z, Matzger AJ.
europepmc +2 more sources
ACS Sustainable Chemistry and Engineering, 2018 We demonstrate a controllable mechanochemical synthesis of cocrystal polymorphs of ascorbic acid (vitamin C) and nicotinamide (vitamin B3) on different scales and without using bulk solvents.
Tomislav Stolar +12 more
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Obtaining Cocrystals by Reaction Crystallization Method: Pharmaceutical Applications [PDF]
Pharmaceutics, 2021 Cocrystals have gained attention in the pharmaceutical industry due to their ability to improve solubility, stability, in vitro dissolution rate, and bioavailability of poorly soluble drugs. Conceptually, cocrystals are multicomponent solids that contain
Isabela Fanelli Barreto Biscaia +3 more
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Superior solubility and dissolution of zaltoprofen via pharmaceutical cocrystal
Turkish Journal of Pharmaceutical Sciences, 2018 Objective: Pharmaceutical cocrystal is a promising tool to enhance solubility and dissolution of poorly soluble drugs. Zaltoprofen (ZFN) is nonsteroidal antiinflammatory drug with prevalent solubility problem.
Prabhakar Panzade, Giridhar Shendarkar
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Pharmaceutical cocrystals model drug–receptor interactions [PDF]
Acta Crystallographica Section A Foundations of Crystallography, 2011 M. Tutughamiarso, E. Egert
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A Randomized, Double-Blind, Two-Treatment, Two-Period, Crossover Study Investigating the Systemic Bioavailability of a Novel Cocrystal Ubiquinol Formulation Compared with a Ubiquinone Formulation in Healthy Adults. [PDF]
Clin Pharmacol Drug DevAbstract Coenzyme Q10 (CoQ10) is a naturally occurring biochemical cofactor found in all human cell membranes in two interconvertible forms: oxidized ubiquinone and reduced ubiquinol. Clinical studies indicate that different CoQ10 formulations have different absorption rates, highlighting research comparing their systemic bioavailability.
Mei X +4 more
europepmc +2 more sources
Pharmaceutics, 2021 Pharmaceutical cocrystal provides an alternative modification strategy for the formulation development of drugs owning to their potential ability to improve the physicochemical properties of active pharmaceutical ingredients (APIs) efficiently by ...
Yanhua Bo +6 more
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Pharmaceutics, 2023 This study describes the preparation, characterization, and influence of the enantiopure vs. racemic coformer on the physico-chemical properties of a pharmaceutical cocrystal.
Panpan Ma +17 more
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Applied Sciences, 2021 Pharmaceutical cocrystallization offers the possibility to modify the physicochemical and biopharmaceutical properties of active pharmaceutical ingredients.
Juan Saulo González-González +4 more
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