Results 41 to 50 of about 666,519 (246)
Cocrystals by Design: A Rational Coformer Selection Approach for Tackling the API Problems
Pharmaceutics, 2023 Active pharmaceutical ingredients (API) with unfavorable physicochemical properties and stability present a significant challenge during their processing into final dosage forms.
Maan Singh +8 more
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Crystals, 2016 Cocrystallization could improve most physicochemical properties of specific active pharmaceutical ingredients, which has great potential in pharmaceutical development.
Yong Du, Qiang Cai, Jiadan Xue, Qi Zhang
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Procedia Chemistry, 2014 AbstractCocrystals are very interesting and useful product. In this paper the main information about cocrystals is presented. It is shown that cocrystals are solid substances, which consist of few components mixed together. There are a lot of ways of cocrystals production and application.
Korotkova, Elena Ivanovna +1 more
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Pharmaceutical Cocrystals and Their Physicochemical Properties [PDF]
Crystal Growth & Design, 2009 This review article will highlight and discuss the advances made over the last 10 years pertaining to physical and chemical property improvements through pharmaceutical cocrystals and, hopefully, draw closer the fields of crystal engineering and pharmaceutical sciences.
Schultheiss, Nate, Newman, Ann
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Complete Cocrystal Formation during Resonant Acoustic Wet Granulation: Effect of Granulation Liquids
Pharmaceutics, 2021 The manufacturing of solid pharmaceutical dosage forms composed of cocrystals requires numerous processes during which there is risk of dissociation into parent molecules.
Ryoma Tanaka +5 more
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Recent Advances in Pharmaceutical Cocrystals: A Focused Review of Flavonoid Cocrystals
Molecules, 2023 Cocrystallization is currently an attractive technique for tailoring the physicochemical properties of active pharmaceutical ingredients (APIs). Flavonoids are a large class of natural products with a wide range of beneficial properties, including anticancer, anti-inflammatory, antiviral and antioxidant properties, which makes them extensively studied.
Jia Xu +6 more
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Pharmaceuticals, 2023 Using cocrystals has emerged as a promising strategy to improve the physicochemical properties of active pharmaceutical ingredients (APIs) by forming a new crystalline phase from two or more components.
Aytug Kara +4 more
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Antibiotics, 2021 Cocrystallization is a promising approach to alter physicochemical properties of active pharmaceutical ingredients (hereafter abbreviated as APIs) bearing poor profile.
Noor Ul Islam +6 more
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Optimized solubility and bioavailability of genistein based on cocrystal engineering
Natural Products and Bioprospecting, 2023 With various potential health-promoting bioactivities, genistein has great prospects in treatment of a series of complex diseases and metabolic syndromes such as cancer, diabetes, cardiovascular diseases, menopausal symptoms and so on.
Zhipeng Wang +10 more
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Crystals, 2019 Pharmaceutical cocrystallization is a useful method to regulate the physical properties of active pharmaceutical ingredients (APIs). Since the cocrystals may form in various API/coformer ratios, identification of the cocrystal composition is the critical
Hyunseon An, Insil Choi, Il Won Kim
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