Results 71 to 80 of about 2,907,976 (379)

ACT001 improves OVX-induced osteoporosis by suppressing the NF-κB/NLRP3 signaling pathway

open access: yesMolecular Medicine
Osteoporosis (OP) is a common systemic metabolic bone disease characterized by the decrease in bone mass and hyperactivity of osteoclasts. ACT001 is approved as an orphan drug by FDA and has shown multiple protective effects against tissue injury ...
Yuan Li   +9 more
doaj   +1 more source

Cis‐unsaturated sphingolipids support growth of sphingoid base‐deficient yeast but impair plasma membrane integrity

open access: yesFEBS Open Bio, EarlyView.
Sphingoid base structures, the sphingolipid backbones, vary among species. We established yeast cells in which the native sphingoid base was replaced with plant‐type bases containing cis or trans double bonds. This is, to our knowledge, the first eukaryotic model mostly composed of sphingolipids containing cis‐unsaturated sphingoid base, providing a ...
Takashi Higuchi   +5 more
wiley   +1 more source

The Fate of SWCNTs in Mouse Peritoneal Macrophages: Exocytosis, Biodegradation, and Sustainable Retention

open access: yesFrontiers in Bioengineering and Biotechnology, 2020
The understanding of toxicological and pharmacological profiles of nanomaterials is an important step for the development and clinical application of nanomedicines.
Ping-Xuan Dong   +11 more
doaj   +1 more source

Toxic Element Contamination of Natural Health Products and Pharmaceutical Preparations

open access: yesPLoS ONE, 2012
Background Concern has recently emerged regarding the safety of natural health products (NHPs)–therapies that are increasingly recommended by various health providers, including conventional physicians.
S. Genuis   +3 more
semanticscholar   +1 more source

Microbial profile of the appendix niche in acute appendicitis: a novel sampling approach

open access: yesFEBS Open Bio, EarlyView.
This study utilized a novel sampling method, ERAT (i.e. endoscopic retrograde appendicitis treatment)‐guided lumen aspiration, to obtain samples from the appendix, and shotgun metagenomic sequencing was performed for in situ characterization of the appendix microbiome in patients with acute appendicitis.
Huimin Ma   +10 more
wiley   +1 more source

A novel approach for denoising electrocardiogram signals to detect cardiovascular diseases using an efficient hybrid scheme

open access: yesFrontiers in Cardiovascular Medicine
BackgroundElectrocardiogram (ECG) signals are inevitably contaminated with various kinds of noises during acquisition and transmission. The presence of noises may produce the inappropriate information on cardiac health, thereby preventing specialists ...
Pingping Bing   +7 more
doaj   +1 more source

Spectrophotometric Determination of Chloramphenicol in Pharmaceutical Preparations [PDF]

open access: yesمجلة التربية والعلم, 2018
A spectrophotometric method for the determination of trace amounts of chloramphenicol has been proposed. This method depends upon the reduction of the nitro to amino group, condensation with promethazine reagent in the presence of cerium (IV) ions to ...
Tamathir A. Hamoudi, Wadala A. Bashir
doaj   +1 more source

Fast and Efficient Monitoring of Diclofenac Dissolution Profile by CE [PDF]

open access: yes, 2014
Capillary electrophoresis (CE) was used to follow Diclofenac tablet dissolution, in very short times and allowing dissolution testing without volume replacement. By using Student´s t test and F-test, this CE method was compared with HPLC.
Delfino, Mario Raul   +3 more
core   +1 more source

Simultaneous Determination of Sitagliptin and Metformin in Pharmaceutical Preparations by Capillary Zone Electrophoresis and its Application to Human Plasma Analysis

open access: yesAnalytical Chemistry Insights, 2012
A novel, quick, reliable and simple capillary zone electrophoresis CZE method was developed and validated for the simultaneous determination of sitagliptin (SG) and metformin (MF) in pharmaceutical preparations. Separation was carried out in fused silica
M. Salim   +4 more
semanticscholar   +1 more source

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