Results 61 to 70 of about 1,013,409 (346)

Tailored novel phosphonate-based hybrid materials by design for diverse applications [PDF]

open access: yes, 2018
Hybrid materials are composed of an organic and an inorganic part, placed together in such a way that the final product has defined structures and properties.
Demadis, Konstantinos D.
core  

Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management

open access: yesMolecular Oncology, EarlyView.
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez   +5 more
wiley   +1 more source

USM DAAD SUMMER SCHOOL STRENGTHENS EXPERTISE IN ELECTROPHYSIOLOGY [PDF]

open access: yes, 2015
PENANG, 16 June 2015 – The recently concluded USM DAAD (Deutscher Akademischer Austauschdienst German Academic Exchange Service) Summer School, jointly organised by Universiti Sains Malaysia (USM) School of Pharmaceutical Sciences and School of Medical
MPRC, Pusat Media & Perhubungan Awam
core  

Selection Of A Filler For Tablets Manufactured With Direct Compression Method Containing Dry Ginger Extract [PDF]

open access: yes, 2019
The preliminary studies of physico-chemical and pharmaco-technological properties of the dry extract of ginger have determined the need for introduction of different groups of excipients for developing a solid dosage form for the treatment of type II ...
Alkhalaf, M. (Malek)   +2 more
core   +3 more sources

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

Direct measurement of molecular mobility and crystallisation of amorphous pharmaceuticals using terahertz spectroscopy. [PDF]

open access: yes, 2016
Despite much effort in the area, no comprehensive understanding of the formation and behaviour of amorphous solids has yet been achieved. This severely limits the industrial application of such materials, including drug delivery where, in principle ...

core   +2 more sources

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser   +14 more
wiley   +1 more source

Recent advances in pharmaceutical sciences V [PDF]

open access: yes, 2015
Reproducció del llibre publicat a: http://www.trnres.com/ebookcontents.php?id=249This E-book is the fifth volume of a series that compiles contributions from different areas of the multidisciplinary field of Pharmaceutical Sciences. The E-book consists
Muñoz-Torrero López-Ibarra, Diego   +2 more
core  

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Leukotriene D4 induces chemotaxis in human eosinophilc cell line, EoL-1 cells via CysLT1 receptor activation

open access: yesHeliyon, 2017
Numerous reports have shown that cysteinyl leukotrienes (CysLTs) contribute to tissue accumulation of eosinophils in allergic airway inflammation. To date, only a few studies have reported that CysLTs promote chemotactic activity of human eosinophils in ...
Hideaki Shirasaki   +2 more
doaj   +1 more source

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