Results 111 to 120 of about 34,898 (217)

Pregabalin dependence, withdrawal, suicidality and psychosis reports: A disproportionality analysis of the Australian adverse events database

British Journal of Clinical Pharmacology, Volume 92, Issue 2, Page 545-555, February 2026.
Aims Globally, Australia has the highest per capita consumption rate of pregabalin, commonly prescribed for neuropathic pain. Emerging evidence suggests pregabalin may be associated with the onset or recurrence of several potentially life‐threatening psychiatric events in some individuals.
Amy G. McNeilage, Ali Gholamrezaei, Bridin Murnion, Suzanne Nielsen, Claire E. Ashton‐James   +4 more
wiley   +1 more source

Pharmacoepidemiology [PDF]

BMJ, 1984
openaire   +3 more sources

Maternal Medication Use in Pregnancy: A Narrative Review on Assessing and Communicating the “Risk” of Birth Defects to the Patient

Pharmacoepidemiology
The state of knowledge regarding the teratogenic effects of maternal use of medications during pregnancy is constantly evolving and is often uncertain. Timely access to high-quality information may reduce prolonged harmful exposures, decrease the number ...
Sura Alwan, Kimberly S. Grant
doaj   +1 more source

Machine learning methods for predicting adverse drug events: A systematic review

British Journal of Clinical Pharmacology, Volume 92, Issue 2, Page 422-444, February 2026.
Abstract Predicting adverse drug events (ADEs) in outpatient settings is crucial for improving medication safety, identifying high‐risk patients and reducing health‐care costs. While traditional methods struggle with the complexity of health‐care data, machine learning (ML) models offer improved prediction capabilities; however, their effectiveness in ...
Niaz Chalabianloo, Fatemeh Ahmadi, Mohammad Ali Omrani, Sheikh S. Abdullah, Neda Rostamzadeh, Atefeh Jafari, Lujain Izzedin, Kamran Sedig, Flory T. Muanda   +8 more
wiley   +1 more source

Can Pharmacovigilance Data Represent a Potential Tool for Early Detection of the Antibiotic Resistance Phenomenon?

Pharmacoepidemiology
Background: Antibiotic resistance represents a growing concern. A new strategy developed to treat severe infections is represented by ceftazidime/avibactam (CZA/AVI).
Cecilia Cagnotta, Alessia Zinzi, Francesca Gargano, Valerio Liguori, Maria Rosaria Campitiello, Alessandro Perrella, Annalisa Capuano, Concetta Rafaniello, Ugo Trama   +8 more
doaj   +1 more source

Pathway‐Informed Machine Learning Identifies Genetic Predictors of High‐Dose Methotrexate‐Induced Mucositis in Pediatric Acute Lymphoblastic Leukemia

Clinical Pharmacology &Therapeutics, Volume 119, Issue 2, Page 447-456, February 2026.
High‐dose methotrexate for pediatric cancer treatment is frequently associated with mucositis, which can lead to delayed or discontinued treatment and impact survival. While individual genetic variants have been implicated, the cumulative impact of genetic variation within relevant biological pathways remains unexplored.
Xiao Yu Cindy Zhang, Erika N. Scott, Hedy Maagdenberg, Alice Man, Kathy H. Li, S. Rod Rassekh, Bruce C. Carleton, Colin J. D. Ross, Wyeth W. Wasserman, Catrina M. Loucks   +9 more
wiley   +1 more source

Cardiovascular Adverse Events Associated with Prostate Cancer Treatment: A Disproportionality Analysis from the Food and Drug Administration Adverse Event Reporting System Database

Pharmacoepidemiology
Background/Objectives: Several drugs used to treat prostate cancer have been reported to cause cardiovascular adverse events, and this study sought to identify the real-world risk.
Connor Frey
doaj   +1 more source

Transferability of Real World Evidence to Support HTA Recommendations in Lower Income European Countries

Health Science Reports, Volume 9, Issue 2, February 2026.
ABSTRACT Background and Aims Lower income European countries (LIECs) have more limited financial resources to cover high‐cost technologies in rare diseases than higher income European countries (HIECs). Our study explores how treatment recommendations in myelodysplastic syndrome (MDS) can be supported in LIECS by transferring real‐world evidence (RWE ...
Zoltán Kaló, Guenka Petrova, Bertalan Németh, Petra Došenović Bonča, Diana Delnoij, Alastair Bennett, Konstantin Tachkov, Yingying Zhang, Noemi Kreif, Saskia Knies, Iga Lipska, Tomas Tesar, Zornitsa Mitkova, Johan Ponten, Anders Viberg, Marian‐Sorin Paveliu, Oresta Piniazkho, Adina Turcu‐Stiolica, Tomáš Doležal, Michal Staňák, Alima Almadiyeva, Rok Hren, Dinko Vitezić, Zsuzsanna Petykó, Wim Goettsch, Andrea Manca   +25 more
wiley   +1 more source

DARE-SAFE: Denominator-Adjusted Rate Estimates of Substance Adverse Events Frequency Evaluation in Pharmaceuticals and Vaccines

Pharmacoepidemiology
Background/Objectives: Controversy exists over the use of passive reporting systems, especially the Vaccine Adverse Event Reporting System, in risk assessment.
Matthew Halma, Joseph Varon
doaj   +1 more source

Risk of myocardial infarction with use of selected nonsteroidal anti-inflammatory drugs in spondyloarthritis patients [PDF]

, 2017
BACKGROUND: Spondyloarthritis (SpA) is associated with increased risk of myocardial infarction (MI); the risk may be due to the underlying inflammatory disease, or also due to medications that increase MI risk, such as certain non-steroidal anti ...
Dubreuil, Maureen
core   +1 more source