Results 121 to 130 of about 34,898 (217)

Value of Clinical Evidence and Health Economics and Outcomes Research (HEOR) Studies

Muscle &Nerve, Volume 73, Issue S1, Page S7-S12, February 2026.
ABSTRACT Randomized controlled trials (RCTs) remain the gold standard for establishing the efficacy and safety of new treatments. However, clinical evidence derived from the systematic analysis of real‐world data generated through routine clinical practice can complement RCT data by offering insights into treatment performance in broader, more ...
Agessandro Abrahao, Malgorzata Ciepielewska, Lorne Zinman   +2 more
wiley   +1 more source

Impact of Incretin Mimetics on Thyroid Cancer Among Patients with Type 2 Diabetes: A Retrospective Cohort Time-to-Event Analysis

Pharmacoepidemiology
Background: Incretin mimetics, including glucagon-like peptide-1 receptor agonists (GLP-1 receptor agonist) and dipeptidyl peptidase-4 (DPP-4) inhibitors, have been increasingly utilized for glycemic control in patients with type 2 diabetes (T2D ...
Michael W. Strand, Daniel Chow, Weining Shen, Jonathan H. Watanabe   +3 more
doaj   +1 more source

Development of the Weight and Emotions Scale (WES)

Obesity Science &Practice, Volume 12, Issue 1, February 2026.
ABSTRACT Objective Obesity and overweight are associated with significant psychosocial burden. Existing patient‐reported outcome (PRO) measures only assess a subset of emotion‐related concepts that are relevant to individuals living with these conditions.
Chisom Kanu, Miriam Kimel, Iris Goetz, Lisa M. Neff, Kristina S. Boye, Marissa Stefan, Jessica Jordan   +6 more
wiley   +1 more source

Treating Opioid Use Disorder on the Inpatient Psychiatric Unit: A Novel Buprenorphine Consultation Service

Pharmacoepidemiology
Background: Opioid Use Disorder (OUD) has claimed the lives of many Americans, with rates of overdose steadily rising over the past decade. Despite having highly effective medications to treat this condition, many providers still hesitate to prescribe ...
Sean T. Lynch, Victor Gordillo, Ashley Sacks, Emily Groenendaal, Lidia Klepacz, Eldene Towey, Stephen J. Ferrando   +6 more
doaj   +1 more source

High‐Dimensional Propensity Scores for Mitigating Confounding: Implementation Using Primary and Secondary Care Data in Hong Kong

Pharmacoepidemiology and Drug Safety, Volume 35, Issue 2, February 2026.
ABSTRACT Purpose Confounding is a key concern in observational studies using healthcare databases. The high‐dimensional propensity score (HDPS) algorithm is an approach for generating and prioritising proxy variables, leveraging all available information in a database to mitigate residual confounding.
Edmund C. L. Cheung, Min Fan, Celine S. L. Chui, Angel Y. S. Wong, John Tazare   +4 more
wiley   +1 more source

Agreement Between Medico-Administrative Database Algorithms and Survey-Based Diagnoses for Depression and Anxiety in Older Adults

Pharmacoepidemiology
Objectives: This study aimed to assess the concordance between depression and anxiety case definitions derived from algorithms based on medico-administrative data and structured interviews aligned with the fourth edition of the Diagnostic and Statistical
Giraud Ekanmian, Carlotta Lunghi, Helen-Maria Vasiliadis, Line Guénette   +3 more
doaj   +1 more source

Psychotropic Use Among Classroom Teachers in Espírito Santo: A Cross‐Sectional Study

Pharmacoepidemiology and Drug Safety, Volume 35, Issue 2, February 2026.
ABSTRACT Purpose To assess the prevalence of psychotropic use among classroom teachers and to identify associated factors. Methods A cross‐sectional study was conducted between January and February 2024 in Espírito Santo, Brazil. The study included teachers from 20 state schools selected through probabilistic sampling.
Yohan Cancilheri Mazzini, Paulo Vitor Ramos Vitori, Kimberly Domingos Schneider, Gustavo Magno Baldin Tiguman, Kérilin Stancine Santos Rocha, Dyego Carlos Souza Anacleto de Araújo   +5 more
wiley   +1 more source

Evaluating Public Behavior toward Antibiotic Use in Riyadh: A Cross-Sectional Study

Pharmacoepidemiology
Background: Antibiotic resistance presents a global challenge. Community awareness of antibiotic use has not been studied extensively in Saudi Arabia. This study aimed to assess public awareness of the appropriate use and indications of antibiotics in ...
Sarah A. Alfagih, Monirah A. Albabtain, Muaath Alfagih, Nouf Alharbi   +3 more
doaj   +1 more source

A Clinical Medication Review Focused on Deprescribing in Older Patients With Hyperpolypharmacy: A Mixed‐Methods Feasibility Study

Basic &Clinical Pharmacology &Toxicology, Volume 138, Issue 2, February 2026.
ABSTRACT To address challenges in deprescribing, we investigated the feasibility of an intervention consisting of a clinical medication review (CMR) focused on deprescribing, supported by a training programme for healthcare providers (HCPs) among older patients with hyperpolypharmacy (≥ 10 chronic medications) in primary care.
Gert Baas, Mette Heringa, Sanne Verdoorn, Henk‐Frans Kwint, Eman Badawy, Jacobijn Gussekloo, Marcel Bouvy   +6 more
wiley   +1 more source

Six‐Year Trends in Real‐World Data Use for Post‐Marketing Surveillance of New Medical Products in Japan

Clinical and Translational Science, Volume 19, Issue 2, February 2026.
ABSTRACT The Ministerial Ordinance on Good Post‐Marketing Study Practice for Drugs was amended by the Ministry of Health, Labour and Welfare (MHLW) in 2018 to clearly define post‐marketing database studies (DBS) as a measure of pharmacovigilance activities for approved medical products in Japan.
Suguru Okami, Kako Shimotsumagari, Yasunari Sadatsuki   +2 more
wiley   +1 more source