Results 1 to 10 of about 69,154 (279)

Economic evaluations of pharmacogenetic and pharmacogenomic screening tests : a systematic review : second update of the literature [PDF]

, 2016
Objective : Due to extended application of pharmacogenetic and pharmacogenomic screening (PGx) tests it is important to assess whether they provide good value for money. This review provides an update of the literature. Methods : A literature search was
Annemans, Lieven, Berm, Elizabeth JJ, Boersma, Cornelis, de Looff, Margot, Postma, Maarten J, van Boven, Job FM, Vegter, Stefan, Wilffert, Bob   +7 more
core   +16 more sources

Pharmacogenetics and Forensic Toxicology: A New Step towards a Multidisciplinary Approach

Toxics, 2021
Pharmacogenetics analyzes the individual behavior of DNA genes after the administration of a drug. Pharmacogenetic research has been implemented in recent years thanks to the improvement in genome sequencing techniques and molecular genetics. In addition
Nunzio Di Nunno, Massimiliano Esposito, Antonina Argo, Monica Salerno, Francesco Sessa   +4 more
doaj   +1 more source

Knowledge, perceptions and confidence of physicians and pharmacists towards pharmacogenetics practice in Kuwait. [PDF]

PLoS ONE, 2018
BACKGROUND:Pharmacogenetics practice has been successfully implemented in many developed countries to enhance personalized medicine and improve clinical and economic outcomes.
Abdullah Albassam, Shahad Alshammari, Ghadeer Ouda, Samuel Koshy, Abdelmoneim Awad   +4 more
doaj   +1 more source

Pharmacogenomic testing and its future in community pharmacy [PDF]

, 2020
Although it is common to see pharmacogenomic testing used North America and Australia, it is not yet part of practice in the UK. With the promise of genomic screening becoming part of the NHS, pharmacists must equip themselves with a knowledge of how the
Wright, David, Youssef, Essra
core   +1 more source

Pharmacogenetics: Knowledge assessment amongst Syrian pharmacists and physicians

BMC Health Services Research, 2021
Background Pharmacogenetics targets genetic variations that influence drug response. It is relatively a new science that has not been vastly employed in most developing countries including Syria. Therefore we aimed at evaluating the depth of knowledge in
Lina Albitar, Ghalia Abou Alchamat
doaj   +1 more source

Pharmacogenetic testing in oncology: a Brazilian perspective

Clinics, 2018
Pharmacogenetics, a major component of individualized or precision medicine, relies on human genetic diversity. The remarkable developments in sequencing technologies have revealed that the number of genetic variants modulating drug action is much higher
Guilherme Suarez-Kurtz
doaj   +1 more source

Genetic Diversity of HLA Class I and Class II Alleles in Thai Populations: Contribution to Genotype-Guided Therapeutics

Frontiers in Pharmacology, 2020
Human leukocyte antigen (HLA) class I and II are known to have association with severe cutaneous adverse reactions (SCARs) when exposing to certain drug treatment. Due to genetic differences at population level, drug hypersensitivity reactions are varied,
Patompong Satapornpong, Patompong Satapornpong, Patompong Satapornpong, Pimonpan Jinda, Pimonpan Jinda, Thawinee Jantararoungtong, Thawinee Jantararoungtong, Napatrupron Koomdee, Napatrupron Koomdee, Chonlawat Chaichan, Chonlawat Chaichan, Jirawat Pratoomwun, Jirawat Pratoomwun, Chalitpon Na Nakorn, Wichai Aekplakorn, Alisa Wilantho, Alisa Wilantho, Chumpol Ngamphiw, Chumpol Ngamphiw, Sissades Tongsima, Sissades Tongsima, Chonlaphat Sukasem, Chonlaphat Sukasem, Chonlaphat Sukasem   +23 more
doaj   +1 more source

Engineering a folic acid-decorated ultrasmall gemcitabine nanocarrier for breast cancer therapy: Dual targeting of tumor cells and tumor-associated macrophages

Acta Pharmaceutica Sinica B, 2022
Combination of passive targeting with active targeting is a promising approach to improve the therapeutic efficacy of nanotherapy. However, most reported polymeric systems have sizes above 100 nm, which limits effective extravasation into tumors that are
Pearl Moharil, Zhuoya Wan, Apurva Pardeshi, Jiang Li, Haozhe Huang, Zhangyi Luo, Sanjay Rathod, Ziqian Zhang, Yuang Chen, Bei Zhang, Christian A. Fernandez, Jingjing Sun, Song Li   +12 more
doaj   +1 more source

Context, ethics and pharmacogenetics [PDF]

, 2006
Most of the literature on pharmacogenetics assumes that the main problems in implementing the technology will be institutional ones (due to funding or regulation) and that although it involves genetic testing, the ethical issues involved in ...
Adam M. Hedgecoe, Akhtar, Anderson, Anon, Bazell, Beauchamp, Beeson, Brodaty, Brushwood, Clarke, DeVries, Emery, Ensom, Evans, Farlow, Farrer, Fox, Ginsburg, Haimes, Haseltine, Hedgecoe, Hedgecoe, Hoffmaster, Hoffmaster, Issa, Issa, Jazwinska, Johnson, Kumar, Kumar, Levine, Lindpaintner, Lindpaintner, McConnell, McLeod, Nelson, Noguchi, Nuffield Council on Bioethics., Palmer, Pfost, Poirier, Post, Relkin, Richard, Rioux, Ritchie, Robertson, Roses, Rothstein, Rusnak, Sadee, Saunders, Shi, Smith, Smith, Sugarman, Vaszar, Wolf, Zussman   +58 more
core   +1 more source

Some aspects of genetics and pharmacogenetics understanding by pharmacy students in Ukraine

Egyptian Journal of Medical Human Genetics, 2015
Background: Prescription and administration of drugs are still carried out without taking into consideration the individual’s needs of a particular patient on the post-Soviet territory.
O.V. Filiptsova, M.N. Kobets, Yu.N. Kobets   +2 more
doaj   +1 more source