Results 121 to 130 of about 57,996 (259)

Insights from a six‐year hair drug analysis compendium in drug‐facilitated crimes involving vulnerable population cases

open access: yesJournal of Forensic Sciences, EarlyView.
Abstract Hair analysis is a well‐established matrix in forensic toxicology, offering a valuable alternative or complement to traditional matrices in diverse contexts, including drug‐facilitated crimes (DFC), elder abuse, and accidental exposure in children.
Amandine Fort   +8 more
wiley   +1 more source

Insights from Bibliometric Analysis of Epilepsy Research in Morocco between 1969 and 2024

open access: yesPsychiatry International
Epilepsy is a critical neurological condition characterized by the disturbance of the excitatory neuron network, resulting in recurrent seizures. It is a serious health problem requiring intensive attention.
Abdelaziz Zennati   +2 more
doaj   +1 more source

Insights from a 6‐year hair drug analysis compendium in drug‐facilitated sexual assault cases

open access: yesJournal of Forensic Sciences, EarlyView.
Abstract Drug‐facilitated sexual assault (DFSA) may involve a diverse array of substances, including illicit drugs, prescription medications, and over‐the‐counter pharmaceuticals. Hair analysis has emerged as a valuable forensic tool, offering an extended window of detection spanning several months. However, interpreting drug concentrations in hair can
Amandine Fort   +8 more
wiley   +1 more source

Considerations for the Use of AAV‐based Gene Therapy in HIV‐Positive Individuals With Haemophilia

open access: yesHaemophilia, EarlyView.
ABSTRACT Introduction There is a high prevalence of human immunodeficiency virus (HIV) infection among the haemophilia community due to treatment in the 1970s and 1980s with contaminated clotting factor. Lifelong treatment regimens for haemophilia and HIV are burdensome alone and pose a particular challenge for individuals living with both conditions ...
Jürgen K. Rockstroh   +5 more
wiley   +1 more source

ALDH2 Polymorphism in Alcohol‐Related Cirrhosis Requiring Liver Transplantation: A Recipient–Donor Analysis

open access: yesHepatology Research, EarlyView.
ABSTRACT Aim Genetic polymorphisms of alcohol‐metabolizing enzymes influence drinking behavior and susceptibility to alcohol‐related liver disease (ALD). This study aimed to clarify the distribution of ALDH2 and ADH1B genotypes in liver transplant recipients with ALD, and to explore associations with post‐transplant drinking behavior using a recipient ...
Noriyo Yamashiki   +3 more
wiley   +1 more source

Inconsistency in race and ethnic classification in pharmacogenetics studies and its potential clinical implications

open access: yesPharmacogenomics and Personalized Medicine, 2019
Frederick Zhang,1 Joseph Finkelstein21Center for Bioinformatics and Data Analytics, Columbia University Irving Medical Center, New York, NY, USA; 2Department of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, NY ...
Zhang F, Finkelstein J
doaj  

Association of TNF and TLR2 genes with blood parameter levels in Mexican patients with schizophrenia

open access: yesBMC Psychiatry
Background Clinical and genetic studies have suggested that immune dysregulation and neuroinflammation are involved in the pathogenesis of schizophrenia.
Héctor Cabello-Rangel   +5 more
doaj   +1 more source

Expanding Precompetitive Multisector Collaborations to Advance Drug Development and Pharmacogenomics. [PDF]

open access: yes, 2020
Do, Thao P   +7 more
core   +2 more sources

Functional Characterization of the Cat and Dog Wild‐Type and Mutant MDR1 Carrier Proteins and Frequency of the MDR1 Gene Mutation in 800 Cats From Germany

open access: yesJournal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT The ATP‐binding cassette transporter MDR1 P‐glycoprotein (syn. ABCB1) is an efflux carrier at the cell membrane that regulates drug absorption, distribution, and elimination. At the blood–brain barrier, MDR1 restricts brain entry of potentially neurotoxic drugs, such as ivermectin. In dogs and cats, MDR1 (syn.
Lisa Siegl   +6 more
wiley   +1 more source

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