Results 151 to 160 of about 69,154 (279)

Induction of Cyp2e1 contributes to asparaginase-induced hepatocyte sensitization to lipotoxicity

Acta Pharmaceutica Sinica B
One of the leading therapies for acute lymphoblastic leukemia (ALL) is the chemotherapeutic agent PEGylated E. coli-derived-l-asparaginase (PEG-ASNase).
Yin Zhu, Yuyin Wang, Keito Hoshitsuki, Da Yang, Lauren Kokai, Xiaochao Ma, Wen Xie, Christian A. Fernandez   +7 more
doaj   +1 more source

Pharmacogenetic risk factors for altered bone mineral density and body composition in pediatric acute lymphoblastic leukemia

, 2009
M.L. te Winkel, Robert D. van Beek, Sabine M.P.F. de Muinck Keizer‐Schrama, André G. Uitterlinden, Wim C.J. Hop, Rob Pieters, Marry M. van den Heuvel‐Eibrink   +6 more
openalex   +2 more sources

The role of sinusoidal endothelial cells and TIMP1 in the regulation of fibrosis in a novel human liver 3D NASH model

Hepatology Communications
Background:. The prevalence of NAFLD is rapidly increasing. NAFLD can progress to NASH, fibrosis, cirrhosis, and HCC, which will soon become the main causes of liver transplantation.
Sander van Riet, Anais Julien, Andrea Atanasov, Åsa Nordling, Magnus Ingelman-Sundberg   +4 more
doaj   +1 more source

Application of rapid genotyping of Warfarin individualized pharmacogenetic variants in Warfarin therapy [PDF]

Defa Huang, Fangfang Xie, Shufang Xiao, M J Cai, Die Hu, Baodian Ling, Fangsheng Wang, Xuan Lin, Fangli Song, Qi Wang, Tianyu Zhong   +10 more
openalex   +1 more source

Utility of patient-derived xenografts to evaluate drug sensitivity and select optimal treatments for individual non-small-cell lung cancer patients

Molecular Medicine
Background Patient-derived xenograft (PDX) is currently considered a preferred preclinical model to evaluate drug sensitivity, explore drug resistance mechanisms, and select individualized treatment regimens.
Xiaoqing Wang, Ju Zhu, Lingling Li, Qilin Zhao, Yutang Huang, Chunjie Wen, Dan Chen, Lanxiang Wu   +7 more
doaj   +1 more source

Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2D6 and CYP2C19 Genotypes and Dosing of Selective Serotonin Reuptake Inhibitors [PDF]

, 2015
J K Hicks, JR Bishop, Katrin Sangkuhl, Müller Dj, Yuan Ji, SG Leckband, JS Leeder, RL Graham, DL Chiulli, Adrián LLerena, TC Skaar, Stuart A. Scott, Julia Stingl, Teri E. Klein, KE Caudle, Andrea Gaedigk   +15 more
openalex   +1 more source

Cartographic atlas of frequency variation for 45 pharmacogenetic markers in populations of Russia and its neighbor states [PDF]

, 2020
Elena Balanovska, VS Petrushenko, Sergey Koshel, Elvira Pocheshkhova, Denis Chernevskiy, KB Mirzaev, Sherzod Abdullaev, OP Balanovsky   +7 more
openalex   +1 more source

Antidepressant Pharmacogenetics [PDF]

American Journal of Psychiatry, 2017
Ajeet B, Singh, Chad A, Bousman
openaire   +2 more sources

Pharmacogenetics of anesthetics [PDF]

, 2008
Kye-Min Kim
openalex   +1 more source

Initial assessment of the benefits of implementing pharmacogenetics into the medical management of patients in a long-term care facility

Pharmacogenomics and Personalized Medicine, 2016
Juan-Sebastian Saldivar, David Taylor, Elaine A Sugarman, Ali Cullors, Jorge A Garces, Kahuku Oades, Joel Centeno AltheaDx, San Diego, CA, USA Abstract: The health care costs associated with prescription drugs are enormous, particularly in patients with ...
Saldivar JS, Taylor D, Sugarman EA, Cullors A, Garces JA, Oades K, Centeno J   +6 more
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