Pharmacogenetics in Community Pharmacy: Global Perspectives and Implementation. [PDF]
Rutkowska K +13 more
europepmc +1 more source
Pharmacogenetics, race, and psychiatry: prospects and challenges
http://dx.doi.org/10.1080 ...
Jones, David S., Perlis, Roy H.
core
Abstract Objective Cenobamate (CNB) is a highly effective antiseizure medication (ASM) for focal drug‐resistant epilepsy (DRE); nevertheless, even with CNB treatment and optimized therapy, a substantial proportion of patients continued to experience seizures.
Ilaria Ciullo +8 more
wiley +1 more source
Genotyping of DPYD and UGT1A1 in Brazilian oncological patients: applying pharmacogenomics in an admixed population. [PDF]
Cereser VHB +3 more
europepmc +1 more source
Ivermectin Toxicity in Humans and Animals: Clinical Spectrum, Mechanisms, and Management
ABSTRACT Ivermectin is a widely used macrocyclic lactone with established efficacy against a broad range of parasitic infections in humans and animals and a long‐standing reputation for clinical safety. However, increasing evidence indicates that ivermectin can produce clinically relevant toxicity under specific conditions, particularly involving the ...
Serkan Yilmaz +3 more
wiley +1 more source
Pharmacogenetics of antidepressant response: a focused review on CYP2C19, CYP2D6, SLC6A4, and HTR2A polymorphisms. [PDF]
Blambila L +3 more
europepmc +1 more source
Acetylation Variability in Elderly Tunisians: Implications for Isoniazid Dose Individualization
Abstract The relationship between age and isoniazid acetylation phenotype remains insufficiently characterized, particularly in elderly populations, where pharmacokinetic variability and susceptibility to toxicity may be increased. This study aimed to characterize isoniazid acetylation phenotypes in elderly Tunisian patients using a phenotypic index ...
Yasmine Khefacha +11 more
wiley +1 more source
Things We Do for No Reason™: Prescribing gabapentinoids for pain
Visual Abstract Abstract Gabapentin and pregabalin are among the most frequently prescribed medications in the United States, with gabapentin in the top 10 and pregabalin in the top 100. Despite FDA approval for only select neuropathic conditions, most use is for off‐label pain indications.
Niti G. Patel +4 more
wiley +1 more source
A randomized trial to evaluate attitudes regarding pharmacogenomics among pregnant and pediatric populations: design and baseline characteristics. [PDF]
Sundermann AC +7 more
europepmc +1 more source
The odds ratios and corresponding 95% confidence intervals for suicide death by 5‐HTTLPR S allele, in main and subgroup analyses. Statistical significance is indicated. ABSTRACT Introduction More than 720 000 individuals die by suicide annually worldwide, making it a major public health concern and a leading cause of death among young people ...
Shohei Okada +11 more
wiley +1 more source

