Results 151 to 160 of about 30,618 (276)

Pharmacogenetics: The ethical issues

, 2001
abstrac
Thomas, S.M.
core  

Clinical pharmacology and prescribing education: An updated medical school curriculum from the British Pharmacological Society

British Journal of Clinical Pharmacology, Volume 92, Issue 6, Page 1787-1808, June 2026.
Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale, Clare Guilding, Jennifer Koenig, Michael Okorie, Reecha Sofat, Simon Maxwell   +5 more
wiley   +1 more source

Mechanism‐informed machine learning for individualized tacrolimus dose adjustment in the early post‐kidney transplant period

British Journal of Clinical Pharmacology, Volume 92, Issue 6, Page 1730-1743, June 2026.
Abstract Aim Tacrolimus dosing in the early post‐kidney transplant period is challenging due to a narrow therapeutic index and substantial interindividual pharmacokinetic (PK) variability. This study aimed to develop and validate mechanism‐informed machine learning (ML) models to support individualized tacrolimus dosing during this critical period ...
Hui Yu, Zihan Qin, Logan S. Smith, Jeong M. Park, Hao‐Jie Zhu   +4 more
wiley   +1 more source

Consistency and clarity of pharmacogenomic guidance in UK medicine patient information leaflets: A cross‐sectional analysis

British Journal of Clinical Pharmacology, Volume 92, Issue 6, Page 1934-1939, June 2026.
Pharmacogenomic (PGx) information has the potential to support the safe and effective use of medicines, yet there is uncertainty about how this information can be best communicated to patients. Summaries of product characteristics (SmPCs) and patient information leaflets (PILs) for all UK‐approved medicines with strong evidence supporting a PGx ...
Parth Narlawar, Chloe Ratcliffe, Videha Sharma, William G. Newman, Munir Pirmohamed, John McDermott   +5 more
wiley   +1 more source

Pharmacogenetics of psychotropic drug response

, 2004
http://dx.doi.org/10.1176/appi.ajp.161.5 ...
Murphy, Greer M., Jr., Malhotra, Anil K., Kennedy, James L.   +2 more
core  

Beta Blocker Toxicity at Therapeutic Doses: A Look Into Carvedilol Use in the Elderly

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Beta‐blocker toxicity does not occur only in overdose situations. In vulnerable populations such as children and the elderly, therapeutic doses may produce cumulative toxic effects similar to those seen in acute overdose. These patients require monitoring that extends beyond basic laboratory investigations to preempt cumulative toxicity.
Samuel Amo‐Tachie
wiley   +1 more source

Limited Visibility and Perception of the Clinical Relevance of Clopidogrel Pharmacogenetics in Cardiology Literature. [PDF]

Clin Transl Sci
Dello Russo C, Venetucci L, Akintola A, Gagliardi D, Ramlogan R, Pirmohamed M.   +5 more
europepmc   +1 more source

Lansoprazole‐Induced Microscopic Colitis Mimicking Anticancer Drug‐Related Diarrhea During Lenvatinib and Pembrolizumab Combination Therapy: A Case Report

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Persistent diarrhea during anticancer therapy may not be attributable to anticancer agents. Our patient presented with diarrhea during lenvatinib–pembrolizumab therapy, likely caused by lansoprazole‐induced microscopic colitis. Even when symptoms closely resemble anticancer drug or immune‐related colitis, drug‐induced colitis due to ...
Shinichi Maruyama, Takuro Hirano, Kazuhiro Fuchinoue, Yoshikiyo Akasaka, Takanori Yoshida, Hiroshi Kanno, Masaru Kato   +6 more
wiley   +1 more source

Pharmacogenetics of alcohol: treatment implications

, 2000
editoria
Busto, Usoa E.
core  

Integrating antibody–drug conjugates into solid tumor oncology: Current standards and future directions

Cancer, Volume 132, Issue S1, 1 June 2026.
Abstract Antibody–drug conjugates (ADCs) represent a major advance in precision oncology, combining the selectivity of monoclonal antibodies with the cytotoxic potency of chemotherapy. By enabling targeted intracellular delivery of highly potent payloads, ADCs aim to maximize antitumor activity while minimizing systemic toxicity. This review summarizes
André Mansinho, Joana Albuquerque, Andreia Lopes, Emiliano Calvo   +3 more
wiley   +1 more source