Results 181 to 190 of about 88,087 (318)

The challenge of pharmacogenetics and pharmacogenomics [PDF]

, 2000
Robert Snedden
openalex   +1 more source

Utility of patient-derived xenografts to evaluate drug sensitivity and select optimal treatments for individual non-small-cell lung cancer patients

Molecular Medicine
Background Patient-derived xenograft (PDX) is currently considered a preferred preclinical model to evaluate drug sensitivity, explore drug resistance mechanisms, and select individualized treatment regimens.
Xiaoqing Wang, Ju Zhu, Lingling Li, Qilin Zhao, Yutang Huang, Chunjie Wen, Dan Chen, Lanxiang Wu   +7 more
doaj   +1 more source

The role of sinusoidal endothelial cells and TIMP1 in the regulation of fibrosis in a novel human liver 3D NASH model

Hepatology Communications
Background:. The prevalence of NAFLD is rapidly increasing. NAFLD can progress to NASH, fibrosis, cirrhosis, and HCC, which will soon become the main causes of liver transplantation.
Sander van Riet, Anais Julien, Andrea Atanasov, Åsa Nordling, Magnus Ingelman-Sundberg   +4 more
doaj   +1 more source

Pharmacogenetics and antipsychotic drugs [PDF]

, 2000
Leo Sher
openalex   +1 more source

Clinical pharmacogenetics implementation consortium guideline (CPIC) for CYP2D6 and CYP2C19 genotypes and dosing of tricyclic antidepressants: 2016 update

Clinical pharmacology and therapy, 2017
J. Hicks, K. Sangkuhl, J. Swen, V. Ellingrod, Daniel J. Müller, K. Shimoda, J. Bishop, E. Kharasch, T. Skaar, A. Gaedigk, H. M. Dunnenberger, T. Klein, K. Caudle, J. Stingl   +13 more
semanticscholar   +1 more source

Pharmacogenetics of N-acetylation polymorphisms of dapsone in Japanese and mainland Chinese populations

, 1988
Yukio Horai, Takashi Ishizaki, Hong-Hao Zhou, Yu Zhang   +3 more
openalex   +1 more source

Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for Pharmacogenetics‐Guided Warfarin Dosing: 2017 Update

Clinical pharmacology and therapy, 2017
Julie A. Johnson, K. Caudle, L. Gong, Michelle Whirl‐Carrillo, C. Stein, S. Scott, M. M. Lee, B. Gage, S. Kimmel, M. Perera, Jeffrey L. Anderson, M. Pirmohamed, T. Klein, N. Limdi, L. Cavallari, M. Wadelius   +15 more
semanticscholar   +1 more source

Severe 5-fluorouracil toxicity secondary to dihydropyrimidine dehydrogenase deficiency. A potentially more common pharmacogenetic syndrome

, 1991
Barry Harris, John T. Carpenter, Robert B. Diasio   +2 more
openalex   +1 more source

Enabling Large-Scale Pharmacogenetic Studies by High-Throughput Mutation Detection and Genotyping Technologies [PDF]

, 2001
Michael Shi
openalex   +1 more source

Pharmacogenetics of stereoselective metabolism of mephenytoin concerning human liver P-450 human -2.

, 1990
Ryuichi Kato
openalex   +2 more sources