Results 21 to 30 of about 69,154 (279)
Pharmacogenetics of analgesic drugs [PDF]
, 2013 • Individual variability in pain perception and differences in the efficacy of analgesic drugs are complex phenomena and are partly genetically predetermined.
Branford, R +4 more
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The basic principals of pharmacogenetics testing in cancer treatment [PDF]
Hospital Pharmacology, 2020 Introduction: Precision medicine is an approach that considers genetics, environment and lifestyle factors when prevent and treat different diseases. The important part of precision medicine is pharmacogenetics, a branch of clinical pharmacology that ...
Cikota-Aleksić Bojana M. +3 more
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Toward a clinical practice guide in pharmacogenomics testing for functional polymorphisms of drug-metabolizing enzymes. Gene/drug pairs and barriers perceived in Spain [PDF]
, 2012 The development of clinica lpractice recommendations or guidelines for the clinical use of biomarkers is an issue of great importance withr regard to adverse drug reactions.The poten-tial of pharmacogenomicbiomarkers has been extensively investigated in
Abad Santos, Francisco +18 more
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Developmental Pharmacogenetics of CYP2D6 in Chinese Children: Loratadine as a Substrate Drug
Frontiers in Pharmacology, 2021 Objective: The elucidation of CYP2D6 developmental pharmacogenetics in children has improved, however, these findings have been largely limited to studies of Caucasian children.
Qian Li +12 more
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Hepatitis C virus pharmacogenomics in Latin American populations: implications in the era of direct-acting antivirals [PDF]
, 2017 In recent years, great progress has been made in the field of new therapeutic options for hepatitis C virus (HCV) infection. The new direct-acting antiviral agents (DAAs) represent a great hope for millions of chronically infected individuals because ...
Caputo, Mariela +4 more
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Pharmacogenetics in Clinical Practice
Prague Medical Report, 2012 Pharmacogenetics is a discipline that investigates how genetic variation relates to the drug efficacy and safety. The goal of pharmacogenetics is a personalized treatment, where according to genotype we would be able to prescribe the most effective drug ...
Hana Bakhouche, O. Slanař
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Introduction : biofutures/biopresents [PDF]
, 2006 Two very different reports produced for the UK government in the last three years have connected the state of our physical health with that of our material wealth. The first of these was produced in 2003 by the Bioscience Innovation and Growth Team (BIGT)
Birch, Kean
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Systematic identification of non-coding pharmacogenomic landscape in cancer
Nature Communications, 2018 In this study the authors build lncRNA-drug response models for 265 anti-cancer agents across 27 cancer types. They report their cancer cell line based lncRNA EN-models are able to effectively predict therapeutic outcome for breast cancer, ovarian cancer,
Yue Wang +6 more
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BMC Cancer, 2019 Background High-risk neuroblastoma with N-Myc amplification remains a therapeutic challenge in paediatric oncology. Antagonism of pro-death Bcl-2 homology (BH) proteins to pro-survival BH members such as Mcl-1 and Bcl-2 has become a treatment approach ...
Stefanie Klenke +5 more
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Pharmacogenetics and individualizing drug treatment during pregnancy [PDF]
, 2014 Pharmacogenetics as a tool to aid clinicians implement individualized pharmacotherapy is utilized in some areas of medicine. Pharmacogenetics in pregnancy is still a developing field.
Haas, David M.
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