Results 21 to 30 of about 38,200 (304)

Pharmacogenomics of Antibiotics [PDF]

International Journal of Molecular Sciences, 2020
Although the introduction of antibiotics in medicine has resulted in one of the most successful events and in a major breakthrough to reduce morbidity and mortality caused by infectious disease, response to these agents is not always predictable, leading to differences in their efficacy, and sometimes to the occurrence of adverse effects.
Stocco G., Lucafo M., Decorti G.
openaire   +4 more sources

Development of the pharmacogenomics and genomics literacy framework for pharmacists

Human Genomics, 2021
Background Pharmacists play a unique role in integrating genomic medicine and pharmacogenomics into the clinical practice and to translate pharmacogenomics from bench to bedside. However, the literature suggests that the knowledge gap in pharmacogenomics
Azhar T. Rahma, Iffat Elbarazi, Bassam R. Ali, George P. Patrinos, Luai A. Ahmed, Mahanna Elsheik, Fatma Al-Maskari   +6 more
doaj   +1 more source

British South Asian ancestry participants views of pharmacogenomics clinical implementation and research: a thematic analysis. [PDF]

, 2023
BACKGROUND: South Asian ancestry populations are underrepresented in genomic studies and therapeutics trials. British South Asians suffer from multi-morbidity leading to polypharmacy.
Islam, MR, Magavern, EF, Genes & Health Research Team, Caulfield, MJ, Clinch, M, Raza, M, Lerner, R, Durrani, F   +7 more
core   +1 more source

Investigation of Biomedical Students’ Attitudes toward Pharmacogenomics and Personalized Medicine: A Cross-Sectional Study

Pharmacy, 2022
Background: The utilization of pharmacogenomics in everyday practice has shown several notable benefits. Keeping in mind the rising trend of applicability of pharmacogenomics and personalized medicine, we sought to compare the attitudes of future ...
Josipa Bukic, Doris Rusic, Dario Leskur, Ana Seselja Perisin, Tin Cohadzic, Marko Kumric, Josko Bozic, Darko Modun   +7 more
doaj   +1 more source

Pharmacogenomics Instruction Depth, Extent, and Perception in US Medical Curricula

Journal of Medical Education and Curricular Development, 2020
Introduction: This descriptive study aimed to evaluate the depth, extent, and perception of pharmacogenomics instruction in schools and colleges of medicine in the United States.
Dara Basyouni, Aymen Shatnawi
doaj   +1 more source

Conference scene : Golden Helix Pharmacogenomics Days : educational activities on pharmacogenomics and personalized medicine [PDF]

, 2012
The Golden Helix Pharmacogenomics Days are high-profile international educational scientific meetings discussing pharmacogenomics and personalized medicine.
Borg, Joseph J., Squassina, Alessio, Patrinos, George P., Severino, Giovanni, Grech, Godfrey, Fenech, Anthony G.   +5 more
core   +1 more source

Pharmacogenomics decision support in the U-PGx project: Results and advice from clinical implementation across seven European countries. [PDF]

, 2022
BackgroundThe clinical implementation of pharmacogenomics (PGx) could be one of the first milestones towards realizing personalized medicine in routine care. However, its widespread adoption requires the availability of suitable clinical decision support
Turner, Richard M, Swen, Jesse J, Steinberger, D., Cheung, Ka-Chun, Davila-Fajardo, C.L., Blagec, K., Ott, S., Patrinos, George P., Turner, Richard M., Ubiquitous Pharmacogenomics Consortium, Samwald, M., Holsappel, Inge, Blagec, Kathrin, Crommentuijn - van Rhenen, Mandy, Crommentuijn-van Rhenen, M., Sunder-Plassmann, Gere, Sunder-Plassmann, G., Ott, Simon, Konta, L., Xu, H., Pirmohamed, M., Turner, R.M., Swen, Jesse J., Cecchin, E., Konta, Lidija, Patrinos, George P, Guchelaar, Henk-Jan, Pirmohamed, Munir, Samwald, Matthias, Steinberger, Daniela, Xu, Hong, Cecchin, Erika, Dávila-Fajardo, Cristina Lucía, Patrinos, G.P., Dolžan, Vita, Guchelaar, H.J., Koopmann, Rudolf, Swen, J.J., Cheung, K.C., Holsappel, I., Koopmann, R., Crommentuijn-van Rhenen, Mandy, Dolzan, V.   +42 more
core   +1 more source

Pharmacogenomics

The Lancet, 2019
Genomic medicine, which uses DNA variation to individualise and improve human health, is the subject of this Series of papers. The idea that genetic variation can be used to individualise drug therapy-the topic addressed here-is often viewed as within reach for genomic medicine. We have reviewed general mechanisms underlying variability in drug action,
Dan M, Roden, Howard L, McLeod, Mary V, Relling, Marc S, Williams, George A, Mensah, Josh F, Peterson, Sara L, Van Driest   +6 more
openaire   +3 more sources

Platelet pharmacogenomics [PDF]

Journal of Thrombosis and Haemostasis, 2010
Platelet responsiveness to conventional antiplatelet therapy underlies a high interindividual variability influenced by various factors. For instance, antiplatelet therapy does not curtail the expected effects in a relevant number of patients as demonstrated by the occurrence of repeated cardiovascular events including stent thrombosis and/or by ...
C S, Zuern, M, Schwab, M, Gawaz, T, Geisler   +3 more
openaire   +2 more sources

Pharmacogenovigilance: a pharmacogenomics pharmacovigilance program [PDF]

, 2014
In this report, we review the importance of pharmacovigilance in detecting postmarketing adverse drug events and the potential for developing pharmacogenovigilance programs by integrating pharmacogenomics with pharmacovigilance.
Khoueiry-Zgheib, Nathalie, Awada, Zainab
core   +1 more source