Results 51 to 60 of about 78,276 (237)
British Journal of Clinical Pharmacology, EarlyView.Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale +5 more
wiley +1 more source
Pharmacogenomics : tailoring drug therapy to individual patients
Journal de la Faculté de Médecine d'OranPharmacogenomics, the study of how individual genetic variations influence drug response, holds tremendous potential for personalized medicine. This comprehensive literature review explores the current landscape of pharmacogenomics, focusing on its role
Eskandar KIROLOS Kirolos
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Pharmacogenomics polygenic risk score for drug response prediction using PRS-PGx methods
Nature Communications, 2022 To try to predict an individual’s drug response using genetic data, most studies have used traditional polygenic risk score (PRS) methods. Here, the authors develop a pharmacogenomics-specific PRS method, which can improve drug response prediction and ...
Song Zhai +3 more
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Molecular Functions of WWOX Potentially Involved in Cancer Development
Cells, 2021 The WW domain-containing oxidoreductase gene (WWOX) was cloned 21 years ago as a putative tumor suppressor gene mapping to chromosomal fragile site FRA16D. The localization of WWOX in a chromosomal region frequently altered in human cancers has initiated
Karim Taouis +3 more
doaj +1 more source
Tailoring therapy for heart failure: the pharmacogenomics of adrenergic receptor signaling. [PDF]
, 2014 Heart failure is one of the leading causes of mortality in Western countries, and β-blockers are a cornerstone of its treatment. However, the response to these drugs is variable among individuals, which might be explained, at least in part, by genetic ...
Barrese, V +3 more
core +2 more sources
British Journal of Clinical Pharmacology, EarlyView.Abstract Aims The study aims to develop a physiologically‐based pharmacokinetic (PBPK) model to quantitatively evaluate the role of ATP‐binding cassette sub‐family B member 1 (ABCB1) and ATP‐binding cassette super‐family G member 2 (ABCG2) in the drug–drug interaction (DDI) between rifampin and linezolid and to predict the impact of high‐dose rifampin ...
Hoang Dat Nguyen +4 more
wiley +1 more source
The genomics of neonatal abstinence syndrome [PDF]
, 2017 Significant variability has been observed in the development and severity of neonatal abstinence syndrome (NAS) among neonates exposed to prenatal opioids.
Cole, F. Sessions +2 more
core +3 more sources
The power of many: when genetics met yeasts and high‐throughput
Biological Reviews, EarlyView.ABSTRACT In recent years, complex technological capabilities have evolved, driven by the need to solve complex and integrative biological questions through global analyses. New equipment allows the scaling up and automation of processes which previously were carried out on a very limited scale.
Víctor A. Tallada, Víctor Carranco
wiley +1 more source
Journal of Pharmaceutical Policy and PracticeBackground Pharmacogenomics, a key component of precision medicine, aims to improve healthcare outcomes. As pharmacists play a pivotal role in this evolving field, an assessment of their preparedness to apply pharmacogenomics is imperative.Methods In ...
Mohanad Odeh +4 more
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Pharmacogenomics and Personalized Medicine, 2023 Ziyad Alrabiah, Wajid Syed, Salmeen D Babelghaith, Mohamed N Al Arifi Department of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh, 11451, Saudi ArabiaCorrespondence: Wajid Syed, Email wali@ksu.edu.saBackground and Aims: It is ...
Alrabiah Z +3 more
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