Results 201 to 210 of about 628,142 (342)

Pharmacokinetics as a Biomarker. [PDF]

Clin Transl Sci
Wagner JA, Singh S, Taylor ZL.
europepmc   +1 more source

Pharmacokinetics of Prednisolone (PSL) during PSL Treatment

, 1986
Eiichi Goshima, Keigo Yasuda, Yoshiyuki FUWA, Kayoko Adachi, Yoshiaki Minamori, Hiroshi Murase, Masanori A. Murayama, Noriyoshi Yamakita, Kiyoshi Miura   +8 more
openalex   +2 more sources

In Situ Lipoprotein‐seeking Dye for in Vivo Real‐Time Imaging of Lipid Dysregulation Diseases

Advanced Science, EarlyView.
This study develops lipoprotein‐seeking NIR‐II dyes that specifically bind circulating lipoproteins. These dyes form ultra‐stable complexes with endogenous lipoprotein, enabling real‐time, high‐contrast imaging of fatty liver and atherosclerotic plaques. Tunable binding kinetics allow customized imaging windows.
Yijing Du, Zetao Dang, Baofeng Xu, Jiajun Xu, Dan Wang, Yuewei Zhang, Shoujun Zhu   +6 more
wiley   +1 more source

Development of a Pregnancy-Specific Physiologically Based Pharmacokinetics (PBPK) Model for Aspirin. [PDF]

CPT Pharmacometrics Syst Pharmacol
Collins-Smith A, Kammala AK, Phelps MA, Wang XM, Menon R, Costantine MM.   +5 more
europepmc   +1 more source

Transmammary-delivered meloxicam in piglets undergoing castration and tail docking: impact on pharmacokinetics and pain biomarkers

, 2015
Jessica L. Bates
openalex   +2 more sources

Inulin‐Based Oral Chemotherapy Modulates Gut Microbiota and Immune Microenvironment through Inhibition of Neutrophil Extracellular Trap Formation for Improving Cancer Therapy

Advanced Science, EarlyView.
Schematic representation of ZIF‐8@OXA@inulin for cancer immunotherapy. Synthesis of ZIF‐8@OXA@inulin. Augmentation of pyroptosis, regulation of gut microbiota, and inhibition of NETs formation by ZIF‐8@OXA@inulin‐mediated comprehensive strategy for antitumor immune response. ABSTRACT Despite the potential of chemoimmunotherapy against colorectal cancer
Zhenhao Li, Jiaqiang Jiang, Yuping Zhou, Xinyuan Mao, Haotian Wen, Zhian Chen, Yutong Wang, Cong Huang, Yanfeng Hu   +8 more
wiley   +1 more source

Vasopressor Strategy in Pediatric Sepsis: A Clinical Pharmacology Perspective. [PDF]

J Pediatr Pharmacol Ther
Green DJ, Watt KM.
europepmc   +1 more source

Population pharmacokinetics of sildenafil in extremely premature infants [PDF]

, 2019
Daniel González, Matthew M. Laughon, P. Brian Smith, Shufan Ge, Namasivayam Ambalavanan, Andrew M. Atz, Gregory M. Sokol, Chi D. Hornik, Dan L. Stewart, Gratias Mundakel, Brenda B. Poindexter, Roger Gaedigk, Mary Mills, Michael Cohen‐Wolkowiez, Karen Martz, Christoph P. Hornik   +15 more
openalex   +1 more source

Pharmacokinetic profiles of three dose rates of morphine sulfate following single intravenous, intramuscular, and subcutaneous administration in the goat

, 2021
Emma Gordon, Levent Dirikolu, Chin‐Chi Liu, Alexander Ulanov, Li Zhong, Matt Welborn, Chance L. Armstrong, Danielle Vallotton, Sarah Keeton, Sarah Camlic, Clare M. Scully   +10 more
openalex   +2 more sources

Fibroblast Activation Protein Promotes Thoracic Aortic Dissection via PLAUR/ITGB1‐Mediated Pro‐inflammatory Macrophage Polarization

Advanced Science, EarlyView.
This study reveals that FAP promotes thoracic aortic dissection (TAD) through a nonenzymatic mechanism involving fibroblast‐macrophage crosstalk via the FAP/PLAUR/ITGB1/FAK axis. Targeting this pathway might offer a promising therapeutic strategy for TAD.
Hongqiao Zhu, Jianlie Wu, Ziyi Xu, Yifei Pei, Zaiping Jing, Jian Zhou, Rui Feng, Junjun Liu   +7 more
wiley   +1 more source