Results 221 to 230 of about 628,142 (342)

Correction to: A Multicentric Clinical Study to Evaluate Pharmacokinetics, Efficacy, and Safety of Immune Globulin Subcutaneous 20% Weekly/Biweekly Dosing in Treatment-Experienced Patients and Loading/Weekly Maintenance Dosing in Treatment-Naïve Patients with Primary Immunodeficiency. [PDF]

J Clin Immunol
Lumry WR, Palumbo M, Hsu C, Hussain I, McNeil D, Bridges T, Wedner HJ, Scarupa M, Mondou E, Nanaware-Kharade N, Hanna K, Coll MQ, Oliveras J.   +12 more
europepmc   +1 more source

Optimization of a Pretargeted Strategy for the PET Imaging of Colorectal Carcinoma via the Modulation of Radioligand Pharmacokinetics

, 2015
Brian M. Zeglis, Christian Brand, Dalya Abdel-Atti, Kathryn E. Carnazza, Brendon E. Cook, Sean Carlin, Thomas Reiner, Jason S. Lewis   +7 more
openalex   +1 more source

pH/ROS‐Responsive Injectable Hydrogel Co‐Loaded with B7‐H3 Blocker and NETs Suppressor Boosts OSCC Synergistic Immunotherapy

Advanced Science, EarlyView.
A pH/ROS‐dual‐responsive injectable hydrogel, formed by dynamic boronic ester and Schiff base crosslinking, co‐delivers enoblituzumab (B7‐H3 blocker) and Cl‐amidine (NETs suppressor). Via localized intratumoral delivery, it synergistically reprograms the immunosuppressive tumor microenvironment, overcomes T cell infiltration barriers, restores ...
Huan Li, Yun Li, Yating Hu, Yanbing Yao, Yaodong He, Jing Li, Jiaqi Tang, Zhenyan Zhao, Yan Wang, Yulun He, Xiaolong Zhang, Xinjie Yang, Jianhua Wei   +12 more
wiley   +1 more source

Correction to "Genotype-Specific Safety and Pharmacokinetics of Cannabidiol in Healthy Volunteers". [PDF]

Clin Transl Sci
europepmc   +1 more source

The toxicology of orally administered Δ⁹-tetrahydrocannabinol in sheep. [PDF]

Toxicol Rep
Stevens SA, Edwards SH, Noble GK, Scrivener CJ, Petzel CE, May CD, Tai ZX, Blake BL, Dods KC, Warne LN, Krebs GL.   +10 more
europepmc   +1 more source

An Insulin‐Exosome‐TNFAIP8 Axis Drives Stromal Fibrosis and Therapeutic Resistance in Pancreatic Cancer

Advanced Science, EarlyView.
In pancreatic ductal adenocarcinoma (PDAC), insulin is associated with activation of PI3K/AKT–RAB3A signaling and enhanced secretion of TNFAIP8‐enriched exosomes from tumor cells. Uptake of these exosomes by fibroblasts is linked to TRIM21‐dependent STAT1 degradation and the emergence of myofibroblastic CAF–associated features, accompanied by increased
Zhenyu Li, Li Chen, Tao Wang, Haiyang Jiang, Huijuan Wang, Mengyu Li, Guanpeng Xie, Chunhua Xi, Han Yan, Chunhui Lu, Chenchen Li, Hanyu Zhu, Feihu Sun, Lingdi Yin, Jun Yu, Yi Miao   +15 more
wiley   +1 more source

Safety and pharmacokinetics of sulfasalazine and its metabolite sulfapyridine for treatment of preterm preeclampsia in Australia (SIP): an early phase, unblinded, single-arm, proof of concept clinical trial. [PDF]

EClinicalMedicine
Kadife E, Decloedt E, Louw V, Abdulla ZB, Kellermann T, Pillay-Fuentes Lorente V, Cluver C, Middleton A, Kaitu'u-Lino TJ, Said JM, Tong S, Brownfoot FC.   +11 more
europepmc   +1 more source

Phase I and pharmacokinetic study of bendamustine hydrochloride in relapsed or refractory indolent B‐cell non‐Hodgkin lymphoma and mantle cell lymphoma

, 2010
Michinori Ogura, Toshiki Uchida, Masafumi Taniwaki, Kiyoshi Ando, Takashi Watanabe, Masanobu Kasai, Yosuke Matsumoto, Daisuke Shimizu, Yoshiaki Ogawa, Ken Ohmachi, Hiroki Yokoyama, Kensei Tobinai, the Japanese Bendamustine Lymphoma Study Group   +12 more
openalex   +2 more sources

Activated Platelet–Released Heat Shock Protein 90α Triggers Autophagy‐Dependent Neutrophil Extracellular Trap Formation and Amplifies Sepsis

Advanced Science, EarlyView.
HSP90α is significantly upregulated in platelets from sepsis patients, with its origin from megakaryocyte‐derived trafficking. Furthermore, activated platelets secrete HSP90α into the extracellular space in both free and exosome‐associated forms. Finally, extracellular HSP90α directly engages TLR4 on neutrophils to induce autophagy, leading to NET ...
Chengbo Wang, Maodong Leng, Chenchen Sun, Jingyu Cao, Linfei Li, Yangyang Jia, Yongshuai Han, Yuchun Liu, Yaodong Zhang, Chenglong Zhang, Yingli Men, Ningyuan Liu, Yibing Cheng, Yixia Zhang, Ya Li, Zhenlong Li, Lidan Cui, Xiangzhan Zhu   +17 more
wiley   +1 more source

Effect of hepatic dysfunction and T tube clamping on FK 506 pharmacokinetics and trough concentrations [PDF]

, 1990
Cadoff, E, Fung, JJ, Jain, AB, Krajack, A, Starzl, TE, Todo, S, Venkataramanan, R   +6 more
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