Results 121 to 130 of about 6,245 (194)

Use of Modeling and Simulation to Inform the Development of Monoclonal Antibodies to Treat Moderate-to-Severe Asthma: A Retrospective Review of EMA Centralized Procedure From 2014 to 2024. [PDF]

CPT Pharmacometrics Syst Pharmacol
Haguet H, Dogné JM, Musuamba FT.
europepmc   +1 more source

Correction to "Beyond the Michaelis-Menten: Evaluation of a tQSSA-Based IVIVE Approach for Predicting In Vivo Intrinsic Clearance from Hepatocyte Assays". [PDF]

CPT Pharmacometrics Syst Pharmacol
europepmc   +1 more source

Utilization of Model-Informed Drug Development in Early Clinical Development: Case Study of a Hb Modulator for Treatment of Sickle Cell Disease. [PDF]

CPT Pharmacometrics Syst Pharmacol
Lim CN, Tania N, Nayak S, Rybin D, Narula J, Arkin S.   +5 more
europepmc   +1 more source

Advancing Pharmacoequity in Low- and Middle-Income Countries via Model Informed Drug Development. [PDF]

Clin Transl Sci
Enzama H, Ojara FW, Haworth IS, Cvijic S, Waitt C, Grasela TH.   +5 more
europepmc   +1 more source

Global Trends in Integrating Machine Learning (ML) with Model-Informed Drug Development (MIDD): A Bibliometric and Systematic Review (2015-2025). [PDF]

Pharmaceutics
Dermawan D, Chtita S, Alotaiq N.
europepmc   +1 more source

Evaluation of the Current ATTR-CM Treatment Landscape via a Mathematical Model of TTR Dissociation and Amyloid Formation. [PDF]

CPT Pharmacometrics Syst Pharmacol
Methven Jeknić S, Ahn-Horst TA, Ji AX, Ju JH, Paull M, Ji SG, Sinha U.   +6 more
europepmc   +1 more source

Cellular Heterogeneity in Drug Uptake Amplifies Pharmacodynamic Variability: A Stochastic PK-PD Analysis. [PDF]

CPT Pharmacometrics Syst Pharmacol
Duong NH, Do TN, Nguyen TT, Phan KQ, Nguyen LT.   +4 more
europepmc   +1 more source

Population Pharmacokinetics of Trastuzumab Rezetecan in Patients With HER2-Expressing or Mutated Advanced Solid Tumors. [PDF]

CPT Pharmacometrics Syst Pharmacol
Gao X, Zhao K, Zhao Y, Zhang Y, Zhao J, Zhao C, Djebli N.   +6 more
europepmc   +1 more source

Autosomal Dominant Tubulointerstitial Kidney Disease Clinical Trial Simulator: Case Reports of Model-Informed Drug Development. [PDF]

CPT Pharmacometrics Syst Pharmacol
Ramesh SS, Rogge M, Kim J, Kang S, Kidd K, Williams A, Roignot J, Blakeslee K, Bleyer AJ, Kim S.   +9 more
europepmc   +1 more source

Immunogenicity Publication Bias and Its Consequences for Predictive Models: A Call for Transparent Reporting. [PDF]

CPT Pharmacometrics Syst Pharmacol
Tascedda S, Hu Z, Grimm HP, Franssen LC.
europepmc   +1 more source