Results 141 to 150 of about 11,033 (240)

Physiologically‐Based Pharmacokinetic Modeling to Investigate Piperaquine Exposure in Pregnant Women Using an Individualized Profile Approach

Clinical and Translational Science, Volume 19, Issue 5, May 2026.
ABSTRACT Malaria in pregnancy poses significant risks to the mother, fetus, and neonate, necessitating effective treatment and prevention strategies. This study explored the application of an individualized (‘virtual twin’) physiologically‐based pharmacokinetic (PBPK) modeling approach to the antimalarial drug piperaquine in pregnant women.
Sonia Khier, Myriam El Gaaloul, Joel Tarning, Nada Abla   +3 more
wiley   +1 more source

Expanding Precompetitive Multisector Collaborations to Advance Drug Development and Pharmacogenomics. [PDF]

, 2020
Do, Thao P, Giacomini, Kathleen M, Huang, Shiew-Mei, Krauss, Ronald M, Kusuhara, Hiroyuki, Sugiyama, Yuichi, Unadkat, Jashvant D, Yee, Sook Wah   +7 more
core   +2 more sources

Response to “mixed‐effects models and the drug titration paradox”

CPT: Pharmacometrics & Systems Pharmacology, 2023
Niels Rode Kristensen, Henrik Agersø
doaj   +1 more source

Pioneering pharmacometrics practice in Korea: an eight-year retrospective analysis of 192 projects from the first dedicated service organization (2016-2024). [PDF]

Transl Clin Pharmacol
Lee SJ, Bae SH, Park J, Hong Y, Jun Y, Han S, Yim DS.   +6 more
europepmc   +1 more source

Evaluating LLM Integration in Pharmacometrics Through a Software Development Perspective. [PDF]

J Pediatr Pharmacol Ther
Barrett K, Callisto SP.
europepmc   +1 more source

Quantitative Systems Pharmacology Modeling Amid the Rise of Agentic AI. [PDF]

CPT Pharmacometrics Syst Pharmacol
Lu J, Desikan R.
europepmc   +1 more source

Causal Directed Acyclic Graphs to Mitigate Confounding Bias in Exposure-Response Analyses. [PDF]

CPT Pharmacometrics Syst Pharmacol
Goulooze SC, Vong C, Hu C, Dumortier T, Mercier F.   +4 more
europepmc   +1 more source

CPT: Pharmacometrics & Systems Pharmacology [PDF]

CPT: Pharmacometrics & Systems Pharmacology, 2013
openaire   +2 more sources

Quantitative Evaluation of Model-Informed Drug Development Implementation in China's Approved Innovative Drugs: From Policy to Practice (2018-2024). [PDF]

CPT Pharmacometrics Syst Pharmacol
Li J, Wang Z, Wei C, He R, Yao Q.
europepmc   +1 more source

Immunogenicity Publication Bias and Its Consequences for Predictive Models: A Call for Transparent Reporting. [PDF]

CPT Pharmacometrics Syst Pharmacol
Tascedda S, Hu Z, Grimm HP, Franssen LC.
europepmc   +1 more source