Results 131 to 140 of about 6,245 (194)

Integration of Time-Varying Pharmacometric Modeling With Cox Regression for Time-to-Event Analysis in NONMEM. [PDF]

CPT Pharmacometrics Syst Pharmacol
Lin CW, Chen PW, Doshi S, Dutta S.
europepmc   +1 more source

Population Pharmacokinetics and Pharmacodynamics of Paracetamol in Malaysian Patients With Plasmodium knowlesi Malaria. [PDF]

CPT Pharmacometrics Syst Pharmacol
Wattanakul T, Cooper DJ, Plewes K, Grigg MJ, Rajahram GS, William T, Dondorp AM, Edstein MD, Birrell GW, Anstey NM, Hoglund RM, Barber BE, Tarning J.   +12 more
europepmc   +1 more source

AI-Powered Lesion-Level Tumor Growth Inhibition Modeling Improves Model Stability and Prognostic Association With PFS. [PDF]

CPT Pharmacometrics Syst Pharmacol
Liu A, Duan C, Maresca K, Pithavala YK, Lu JT, Guo CC, Hibma JE.   +6 more
europepmc   +1 more source

Pharmacokinetic Model Based Sensitivity Analysis to Lower Recruitment Burden for Young Children Requiring Intravenous Immunoglobulin G Replacement. [PDF]

CPT Pharmacometrics Syst Pharmacol
Dumas T, Mehr S, Avila R, Doman A, Kestenberg K, Melamed I.   +5 more
europepmc   +1 more source

The Regularized Horseshoe for Covariate Selection Improves Convenience and Predictive Performance in Population PK/PD Models. [PDF]

CPT Pharmacometrics Syst Pharmacol
Pourzanjani A, Davis C.
europepmc   +1 more source

Learning Covariate Relations in Disease Progression Models Using Symbolic Neural Networks. [PDF]

CPT Pharmacometrics Syst Pharmacol
Sundell J, Wahlquist Y, Kjellsson MC, Karlsson MO, Soltesz K.   +4 more
europepmc   +1 more source

Copulas for Covariate Simulation in Pharmacometrics. [PDF]

CPT Pharmacometrics Syst Pharmacol
Guo Y, Guo T, van Hasselt JGC, Zwep LB.
europepmc   +1 more source

Adaptive Dosing Trial Simulation Framework to Inform Dose Optimization: Case Study Using Longitudinal PKPD Models With PF-06804103 Phase 1 Data in Participants With Human Epidermal Growth Factor Receptor 2 (HER2) Positive and Low Solid Tumors. [PDF]

CPT Pharmacometrics Syst Pharmacol
Li J, Zhou L, Leung ACF, Yin D, Chen X.
europepmc   +1 more source

Machine Learning Meets Pharmacokinetics: A Comparative Analysis of Predictive Models for Plasma Concentration-Time Profiles. [PDF]

CPT Pharmacometrics Syst Pharmacol
Jost F, Giegerich C, Grebner C, Matter H, Cordes H.   +4 more
europepmc   +1 more source

Impact of Event-Related Treatment Modifications in Exposure-Response Analyses of Repeated Time-to-Event Data. [PDF]

CPT Pharmacometrics Syst Pharmacol
Goulooze SC, Snelder N, Eissing T, Garmann D.   +3 more
europepmc   +1 more source