Results 91 to 100 of about 815,394 (267)

Pharmacy trust [PDF]

British Dental Journal, 2020
openaire   +2 more sources

Characterization of Clinical Phenotype to Glial Fibrillary Acidic Protein Concentrations in Alexander Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine the concentration of glial fibrillary acidic protein (GFAP) in cerebrospinal fluid (CSF) and plasma in Alexander disease (AxD) and whether GFAP levels are predictive of disease phenotypes. Methods CSF and plasma were collected (longitudinally when available) from AxD participants and non‐AxD controls.
Amy T. Waldman, Asako Takanohashi, Joshua Y. Joung, Geraldine W. Liu, Kaley Arnold, Amy Pizzino, Walter Faig, Sarah Woidill, Sona Narula, Adeline L. Vanderver   +9 more
wiley   +1 more source

Gold/Prussian Blue-Based Nanocomposites with Dual Nanozyme Activities Exert a Synergistic Effect of Starvation Therapy and Sonodynamic Therapy in the Treatment of Liver Cancer

International Journal of Nanomedicine
Shengnan Huang,1,2,* Chengzhi Song,3,* Tengyue Zhao,4,* Yefei Yang,4 Zhiwei Yao,4 Shaofeng Duan,5 Wanyi Chen,6 Lixian Li,6 Xiaogang Hu,6 Chunming Li,6 Yurong Hu4 1Academy of Chinese Medical Sciences, Henan University of Chinese ...
Huang S, Song C, Zhao T, Yang Y, Yao Z, Duan S, Chen W, Li L, Hu X, Li C, Hu Y   +10 more
doaj  

Clinically Relevant Outcome Measures in Women With Adrenoleukodystrophy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Adrenoleukodystrophy is a rare inherited peroxisomal disease caused by pathogenic variants in the ABCD1 gene located on the X chromosome. Although the most severe central nervous system and adrenal complications typically affect only men with adrenoleukodystrophy, the majority of women develop myeloneuropathy symptoms in adulthood.
Chenwei Yan, Elizabeth I. Pierpont, Amena S. Fine, Reena V. Kartha   +3 more
wiley   +1 more source

Dosing Optimization of Lamotrigine in Peripregnancy Epilepsy Through PopPK Modelling and Simulation

Drug Design, Development and Therapy
Jiping Huo,1,2,* Yilin Liu,3,* Jiayu Yang,1,2,* Meng Chen,4,* Li Yang,1 Lijun Wang,5 Dongjie Zhang,1 Tongtong Liu,1 Wanli Gao,5 Haibin Dai,4 Shenghui Mei,1,2 Zhigang Zhao1,2 1Department of Pharmacy, Beijing Tiantan ...
Huo J, Liu Y, Yang J, Chen M, Yang L, Wang L, Zhang D, Liu T, Gao W, Dai H, Mei S, Zhao Z   +11 more
doaj  

Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler, Vivian Maas, Arian Taheri Amin, Jennifer Faber, Tamara Schaprian, Katharina Hill, Matthis Synofzik, Lisa H. Graf, Heike Jacobi, Manuela Lima, Ana F. Ferreira, Bart P. van de Warrenburg, Ilse H. J. Willemse, Dagmar Timmann, Andreas Thieme, Paola Giunti, Hector Garcia‐Moreno, Magda M. Santana, Jeannette Hübener‐Schmid, Elin H. Davies, Thomas Klockgether   +20 more
wiley   +1 more source

Simultaneous Determination of Venetoclax and Posaconazole in Human Plasma by UPLC-MS/MS: Application to Therapeutic Drug Monitoring in Acute Myeloid Leukemia Patients

Drug Design, Development and Therapy
Xiaohai Chen,* Hualu Wu,* Haoxin Fu, Peiqi Wang, Lu Cao, Ruibin Li, Ruanjuan Zhan, Ren-Ai Xu Department of Pharmacy, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, People’s Republic of China*These ...
Chen X, Wu H, Fu H, Wang P, Cao L, Li R, Zhan R, Xu RA   +7 more
doaj  

Brainstem and Cerebellar Volume Loss and Associated Clinical Features in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Progressive Supranuclear Palsy (PSP) is a neurodegenerative ‘tauopathy’ with predominating pathology in the basal ganglia and midbrain. Caudal tau spread frequently implicates the cerebellum; however, the pattern of atrophy remains equivocal.
Chloe Spiegel, Timothy P. Siejka, Cassandra Marotta, Josh J. Y. Lee, Kelly Bertram, Terence J. O'Brien, Meng Law, Lucy Vivash, Ian H. Harding   +8 more
wiley   +1 more source

Impact of a CMO-Based Pharmaceutical Care Model on 3-HIT Criteria in Older People Living with HIV: The DIS3HIT Project

Patient Preference and Adherence
María Roldán Galnares,1 Ramón Morillo-Verdugo,1 María de las Aguas Robustillo-Cortes,1 Manuel Vélez-Díaz-Pallarés,2 María José Company Albir,3 Beatriz Proy Vega,4 Laura Losa López,5 Laura Marín Ventura,6 María Ferris Villanueva,7 Oihana Mora ...
Roldán Galnares M, Morillo-Verdugo R, Robustillo-Cortes MDLA, Vélez-Díaz-Pallarés M, Company Albir MJ, Proy Vega B, Losa López L, Marín Ventura L, Ferris Villanueva M, Mora Atorrasagasti O, Gutiérrez E   +10 more
doaj  

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source