Results 101 to 110 of about 76,692 (224)

TPP-related mitochondrial targeting copper (II) complex induces p53-dependent apoptosis in hepatoma cells through ROS-mediated activation of Drp1

Cell Communication and Signaling, 2019
Background In recent years, copper complexes have gradually become the focus of potential anticancer drugs due to their available redox properties and low toxicity. In this study, a novel mitochondrion-targeting copper (II) complex, [Cu (ttpy-tpp)Br2] Br
Jiangjuan Shao, Mengmeng Li, Zijian Guo, Chun Jin, Feng Zhang, Chunyan Ou, Yaochen Xie, Shanzhong Tan, Zhenyi Wang, Shizhong Zheng, Xiaoyong Wang   +10 more
doaj   +1 more source

Call for Standardizing Uncaria rhynchophylla as the Sole Origin of Uncariae Ramulus cum Uncis

Phytochemical Analysis, Volume 36, Issue 7, Page 1959-1973, October 2025.
ABSTRACT Background Uncariae Ramulus cum Uncis (URCU) is a widely used traditional Chinese medicine (TCM) for treating neurodegenerative disorders. The Chinese Pharmacopeia recognizes five Uncaria species as authorized botanical sources of URCU; however, there is currently no established quality control method for individual species.
Hau‐Yee Fung, Cheuk‐Hei Lai, Qianran Li, Hau‐Yee Kong, Lifeng Li, Quanbin Han   +5 more
wiley   +1 more source

Quality Analysis of Raw Material and Products of Goat Bezoar (Houzao), a Mysterious Traditional Medicine

Phytochemical Analysis, Volume 36, Issue 7, Page 2182-2196, October 2025.
Goat bezoar is a precious imported Chinese Medicine widely used for centuries in pediatric treatments. However, its unclear chemical profile brings challenge for the identification and the establishment of quality standards. In this study, qualitative and quantitative determination methods of goat bezoar chemical profile were well developed and ...
Sing‐Wan Pun, Hau‐Yee Fung, Peili Zhu, Zhu Zhang, Hanting Hu, Yinan Feng, Zhongzhen Zhao, Lifeng Li, Quanbin Han   +8 more
wiley   +1 more source

Systematic optimization and evaluation of culture conditions for the construction of circulating tumor cell clusters using breast cancer cell lines

BMC Cancer
Background Circulating tumor cell (CTC) clusters play a critical role in carcinoma metastasis. However, the rarity of CTC clusters and the limitations of capture techniques have retarded the research progress.
Jueyao Zou, Qiong Chen, Yong He, Yanhong Pan, Han Zhao, Junfeng Shi, Zhonghong Wei, Suyun Yu, Yang Zhao, Xin Han, Yin Lu, Wenxing Chen   +11 more
doaj   +1 more source

Composition of the volatile oils of the Citrus bigaradia, Citrus limon and Citrus deliciosa

Journal of Medicinal Plants, 2004
Composition of the volatile oils of the C.bigaradia, C.limon and C.delicosa have been investigated. The plant materials (leaves) were collected in spring 2000 from Corta (The medicinal plants garden) near Tonecabon, North of Iran. The oils were collected
M Mosaddegh, M Kamalinejad, A Dehmaoobad Sharifabadi, B Esfahani   +3 more
doaj  

Pharmacy, theoretical and practical Including arithmetic of pharmacy, Adsel A. Ruddiman, Phar.M., M.D., Professor of Pharmacy and Materia Medica, Department of Pharmacy, Vanderbilt University. First edition, octavo, cloth, 267 pages. Price, $1.75. Published by John Wiley & Sons, Inc., New York, 1917 [PDF]

, 1917
Robert P. Fischelis
openalex   +1 more source

Single‐cell sequencing and mass spectrometry imaging reveal the multicellular compartmentalization map of plant triterpenes: A ginsenoside in Panax ginseng example

Plant Biotechnology Journal, Volume 23, Issue 10, Page 4461-4476, October 2025.
Summary Revealing the multicellular compartmentalization map is crucial for plant breeding and metabolism regulation. Despite the importance of triterpenes as active compounds, there has been no report on their biosynthetic multicellular mapping. In this study, ginsenosides are used as an example to reveal the multicellular compartmentalization map of ...
Rubing Wang, Luyao Zhang, Xia Li, Wensong Sun, Yike Wang, Luqi Huang, Juan Wang, Wenyuan Gao, Lanping Guo   +8 more
wiley   +1 more source

Integration of network pharmacology, transcriptomics and single-cell sequencing to explore the effect of Rougan Keli in alleviating liver cirrhosis

Chinese Medicine
Background The progression of liver cirrhosis leads to severe complications, significantly threatening the survival and prognosis of patients. Rou gan keli (Rgkl), a herbal formula derived from classical prescriptions, has used clinically over two ...
Chengbo Jin, Tianle Ma, Yiheng Zhang, Xujing Gu, Tong Zhu, Xinyu Wu, Xin Ding, Suzhou Huang, Yulan Wang, Zhipeng Chen, Huihua Fang, Li Wu   +11 more
doaj   +1 more source

Inhibition of FAK promotes pancreatic cancer immunotherapy by mediating CXCL10 secretion to enhance CD8+ T cell infiltration

OncoImmunology
Immunotherapy has demonstrated potential in treating various malignant tumors, but its efficacy in pancreatic cancer (PC) remains limited, possibly due to the dense stromal components and immunosuppressive microenvironment of PC.
Yu-Chen Shi, Qingling An, Na Tang, Yong-Qiang Zhang, Shu-Qiao Xing, Fan Song, Xiao-Qiang Li   +6 more
doaj   +1 more source

MATERIA MEDICA, THERAPEUTICS, MEDICAL PHARMACY, PRESCRIPTION-WRITING, AND MEDICAL LATIN [PDF]

, 1903
William Schleif
openalex   +1 more source