Results 61 to 70 of about 84,518 (238)

A Base‐Mediated Rearrangement of the Benzylic 1,5‐Hexadipyridynyl Moiety

ChemPlusChem, EarlyView.
A rearrangement unheard of! When exposed to base, benzylic 1,5‐hexadipyridynyl moieties skip a beat—disregarding Cope‐like rearrangement and instead readily rearrange through a deprotonation–reprotonation–electrocyclization cascade. The result is a highly rigid vinyl‐pyridine cyclobutene, fashioned via a novel pathway.A previously unrecognized base ...
Wouter A. Remmerswaal, Thai‐Tony Nguyen, Zijian Han, Fedor Krasovski Slobodian, Ruisheng Xiong, Vadim Kessler, Zhijian Xu, Weiliang Zhu, Mate Erdelyi   +8 more
wiley   +1 more source

Garuda 5 (khyung lnga): Ecologies of Potency and the Poison-Medicine Spectrum of Sowa Rigpa’s Renowned ‘Black Aconite’ Formula [PDF]

, 2019
This article focuses on ethnographic work conducted at the Men-Tsee-Khang (Dharamsala, India) on Garuda 5 (khyung lnga), a commonly prescribed Tibetan medical formula.
van der Valk, Jan M. A.
core   +1 more source

Astragaloside IV accelerates hematopoietic reconstruction by improving the AMPK/PGC1α-mediated mitochondrial function in hematopoietic stem cells

Chinese Medicine
Background Radiotherapy can damage hematopoietic stem cells (HSC) in bone marrow, leading to impaired hematopoietic function. Current treatments mainly target differentiated hematopoietic progenitor cells, which may accelerate their depletion ...
Ling Zhang, Wanqi Xu, Yueying Zeng, Long Wang, Jiesi Luo, Xiaogang Zhou, Qibing Mei, Dalian Qin, Anguo Wu, Jianming Wu, Feihong Huang   +10 more
doaj   +1 more source

Efficient Synthesis of 2,3′-Spirobi (Indolin)-2′-Ones and Preliminary Evaluation of Their Damage to Mitochondria in HeLa Cells

Frontiers in Pharmacology, 2022
A novel formal (4 + 1) annulation between N-(o-chloromethyl)aryl amides and 3-chlorooxindoles through in situ generated aza-ortho-QMs with 3-chlorooxindoles is reported for the synthesis of a series of 2,3′-spirobi (indolin)-2′-ones in high yields. Under
Huajie Li, Huajie Li, Zhenjie Yu, Zhenjie Yu, Haoyi Sun, Haoyi Sun, Bo Liu, Bo Liu, Xin Wang, Xin Wang, Zhe Shao, Zhe Shao, Meiling Wang, Meiling Wang, Weilin Xie, Weilin Xie, Xingang Yao, Qingqiang Yao, Qingqiang Yao, Ying Zhi, Ying Zhi   +20 more
doaj   +1 more source

Saikosaponin b1 Attenuates Liver Fibrosis by Blocking STAT3/Gli1 Interaction and Inducing Gli1 Degradation

Exploration, EarlyView.
Saikosaponin b1 attenuates liver fibrosis by competitively disrupting the interaction between signal transducer and activator of transcription 3 (STAT3) and glioma‐associated oncogene‐1 (Gli1) in the activated hepatic stellate cells (HSCs). The blocked interaction of STAT3 and Gli1 promotes the degradation of Gli1, inhibits Gli1 transcriptional ...
Meiyu Shao, Xiaoqing Zhang, Jiamei Sun, Hongyan Dong, Xin Han, Qiao Yang, Roufen Chen, Liteng Shen, Lei Xu, Lu Wang, Bo Zhu, Dongxin Tang, Shuosheng Zhang, Keda Lu, Mengyun Peng, Gang Cao   +15 more
wiley   +1 more source

Old School Catalog 1912-13, Chicago College of Medicine and Surgery [PDF]

, 1912
https://scholar.valpo.edu/oldschoolcatalogs/1010/thumbnail ...
Valparaiso University
core   +1 more source

Anti-atherosclerotic activity and mechanism of a ginsenoside derivative CK201

陆军军医大学学报, 2023
Objective To explore the anti-atherogenic activity and mechanism involved of ginsenoside derivative CK201 by ApoE-/- mouse and human umbilical vein endothelial cells (HUVECs).
RAN Xiaodong, LUO Mingming, WANG Jiawei, HUANG Yan, LI Xiaohui   +4 more
doaj   +1 more source

Exploring Regulatory Frameworks for Exosome Therapy: Insights and Perspectives

Health Care Science, EarlyView.
ABSTRACT Extracellular vesicles (EVs) have emerged as a promising technology for diagnostic and therapeutic applications in clinical settings over the past decade. However, their advancement is hindered by complex technological and regulatory challenges.
Qiushi Li, Yuxia Li, Jiaqing Shao, Jianhua Sun, Lan Hu, Xia Yun, Chen Liuqing, Likun Gong, Shuxia Wu   +8 more
wiley   +1 more source

A prescriptions list of 1546 [PDF]

, 1989
A prescriptions list for Santo Spirito patients dated 1546, the earliest of its nature found to date, is discussed. Light is thrown on the activities of the hospital, its medical staff, the patients, and the state of the art of medicine in Malta at the ...
Fiorini, Stanley
core  

Call for Standardizing Uncaria rhynchophylla as the Sole Origin of Uncariae Ramulus cum Uncis

Phytochemical Analysis, EarlyView.
ABSTRACT Background Uncariae Ramulus cum Uncis (URCU) is a widely used traditional Chinese medicine (TCM) for treating neurodegenerative disorders. The Chinese Pharmacopeia recognizes five Uncaria species as authorized botanical sources of URCU; however, there is currently no established quality control method for individual species.
Hau‐Yee Fung, Cheuk‐Hei Lai, Qianran Li, Hau‐Yee Kong, Lifeng Li, Quanbin Han   +5 more
wiley   +1 more source