Results 81 to 90 of about 88,090 (243)

Identification of Candidate Biomarkers Correlated With the Pathogenesis and Prognosis of Non-small Cell Lung Cancer via Integrated Bioinformatics Analysis

Frontiers in Genetics, 2018
Background and Objective: Non-small cell lung cancer (NSCLC) accounts for 80–85% of all patients with lung cancer and 5-year relative overall survival (OS) rate is less than 20%, so that identifying novel diagnostic and prognostic biomarkers is urgently ...
Mengwei Ni, Xinkui Liu, Jiarui Wu, Dan Zhang, Jinhui Tian, Jinhui Tian, Ting Wang, Shuyu Liu, Ziqi Meng, Kaihuan Wang, Xiaojiao Duan, Wei Zhou, Xiaomeng Zhang   +12 more
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The First 125 Years : 1838-1963 [PDF]

, 1963
The Medical College of Virginia (MCV) marked the 125th anniversary of its founding with a year-long celebration in 1963, culminating in the publication of The First 125 Years. Issued as hard- and soft-back publications in the college\u27s bulletin series,

core   +1 more source

Xuetongsu attenuates bone destruction in rheumatoid arthritis by suppressing RANKL/RANK/NFATc1 pathway to inhibit osteoclastogenesis and bone resorption

Bone & Joint Research
Aims: Bone destruction is a pivotal pathological factor in the development of joint disability in rheumatoid arthritis (RA) patients, and there is a paucity of safe and effective drugs targeting bone destruction.
Hao Zheng, Yasi Deng, Bin Li, Juan Huang, Jinzhi Liu, Yupei Yang, Yuxin Chen, Linxi Mao, Yamei Li, Yuexuan Liu, Wei Wang, Huanghe Yu   +11 more
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TPP-related mitochondrial targeting copper (II) complex induces p53-dependent apoptosis in hepatoma cells through ROS-mediated activation of Drp1

Cell Communication and Signaling, 2019
Background In recent years, copper complexes have gradually become the focus of potential anticancer drugs due to their available redox properties and low toxicity. In this study, a novel mitochondrion-targeting copper (II) complex, [Cu (ttpy-tpp)Br2] Br
Jiangjuan Shao, Mengmeng Li, Zijian Guo, Chun Jin, Feng Zhang, Chunyan Ou, Yaochen Xie, Shanzhong Tan, Zhenyi Wang, Shizhong Zheng, Xiaoyong Wang   +10 more
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Composition of the volatile oils of the Citrus bigaradia, Citrus limon and Citrus deliciosa

Journal of Medicinal Plants, 2004
Composition of the volatile oils of the C.bigaradia, C.limon and C.delicosa have been investigated. The plant materials (leaves) were collected in spring 2000 from Corta (The medicinal plants garden) near Tonecabon, North of Iran. The oils were collected
M Mosaddegh, M Kamalinejad, A Dehmaoobad Sharifabadi, B Esfahani   +3 more
doaj  

Systematic optimization and evaluation of culture conditions for the construction of circulating tumor cell clusters using breast cancer cell lines

BMC Cancer
Background Circulating tumor cell (CTC) clusters play a critical role in carcinoma metastasis. However, the rarity of CTC clusters and the limitations of capture techniques have retarded the research progress.
Jueyao Zou, Qiong Chen, Yong He, Yanhong Pan, Han Zhao, Junfeng Shi, Zhonghong Wei, Suyun Yu, Yang Zhao, Xin Han, Yin Lu, Wenxing Chen   +11 more
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Integration of network pharmacology, transcriptomics and single-cell sequencing to explore the effect of Rougan Keli in alleviating liver cirrhosis

Chinese Medicine
Background The progression of liver cirrhosis leads to severe complications, significantly threatening the survival and prognosis of patients. Rou gan keli (Rgkl), a herbal formula derived from classical prescriptions, has used clinically over two ...
Chengbo Jin, Tianle Ma, Yiheng Zhang, Xujing Gu, Tong Zhu, Xinyu Wu, Xin Ding, Suzhou Huang, Yulan Wang, Zhipeng Chen, Huihua Fang, Li Wu   +11 more
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Inhibition of FAK promotes pancreatic cancer immunotherapy by mediating CXCL10 secretion to enhance CD8+ T cell infiltration

OncoImmunology
Immunotherapy has demonstrated potential in treating various malignant tumors, but its efficacy in pancreatic cancer (PC) remains limited, possibly due to the dense stromal components and immunosuppressive microenvironment of PC.
Yu-Chen Shi, Qingling An, Na Tang, Yong-Qiang Zhang, Shu-Qiao Xing, Fan Song, Xiao-Qiang Li   +6 more
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TCF-1 and TOX regulate the memory formation of intestinal group 2 innate lymphoid cells in asthma

Nature Communications
Immune memory has been expanded to group 2 innate lymphoid cells (ILC2s), but the cellular and molecular bases remain incompletely understood. Based on house dust mite (HDM)-induced mice asthma models and human samples, we applied flow cytometry ...
Kaifan Bao, Xiaoqun Gu, Yajun Song, Yijing Zhou, Yanyan Chen, Xi Yu, Weiyuan Yuan, Liyun Shi, Jie Zheng, Min Hong   +9 more
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