Results 91 to 100 of about 2,076,023 (303)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Phase control of a longitudinal momentum entangled photon state by a deformable membrane mirror

, 2009
We propose a paradigmatic demonstration of the potentialities of a deformable mirror for closed-loop control of a two-photon momentum-entangled state, subject to phase fluctuations.
Abouraddy, Andrea Chiuri, Barbieri, Barreiro, Bechmann-Pasquinucci, Bonato, Bonora, Brida, Briegel, Chen, Clafin, Cristian Bonato, Fernandez, Giorgio Milani, Giuseppe Vallone, Hartmann, Knutsson, Minár, Paolo Mataloni, Paolo Villoresi, Rarity, Rossi, Schuck, Stefano Bonora, Thew, Vallone, Vallone, Vallone, Wei, Zeek   +29 more
core   +1 more source

Controlled wide-range quadrature phase-shift network

Electronics Letters, 1969
A system is described which produces a 90° phase shift for a wide range of single-frequency input signals. Thus, whilst it will not handle wideband input signals, it may be useful for such applications as N-path and quadrature modulation filters where the provision of variable-frequency quadrature carrier signals allows the position of the passband to ...
openaire   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

High-Efficiency Stacked Half-Bridge Sigma Topology for Wide Input Range and High Step-Down Application

IEEE Open Journal of Power Electronics
In wide input range and high step-down application, conventional Sigma converter suffers from the problem of small duty cycle and low efficiency of the internal Buck converter.
Zhoulong Wang, Li Zhang
doaj   +1 more source

A Control Allocation System for Automatic Detection and Compensation of Phase Shift Due to Actuator Rate Limiting [PDF]

, 2011
This paper proposes a control allocation system that can detect and compensate the phase shift between the desired and the actual total control effort due to rate limiting of the actuators.
Acosta, Diana, Kolmanovsky, Ilya V., Yildiz, Yidiray   +2 more
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Phase-Shift Control for Enhancing Misalignment Tolerance in UCA-Based OAM-MIMO Systems

IEEE Access
This paper presents a novel approach for achieving high-capacity transmission utilizing sub-terahertz (THz) radio orbital angular momentum (OAM) multiplexing, specifically in scenarios where the radio link is susceptible to antenna misalignment. We focus
Norifumi Kamiya, Masahiro Kawai, Eisaku Sasaki   +2 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source