Results 51 to 60 of about 1,845 (260)

How fast does the WallGo? A package for computing wall velocities in first-order phase transitions

Journal of High Energy Physics
WallGo is an open-source software designed to compute the bubble wall velocity in first-order cosmological phase transitions. Additionally, it evaluates the energy budget available for generating gravitational waves.
Andreas Ekstedt, Oliver Gould, Joonas Hirvonen, Benoit Laurent, Lauri Niemi, Philipp Schicho, Jorinde van de Vis   +6 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Steady-state bubbles beyond local thermal equilibrium

Journal of High Energy Physics
We investigate the hydrodynamic solutions for expanding bubbles in cosmological first-order phase transitions going beyond local thermal equilibrium approximation.
Tomasz Krajewski, Marek Lewicki, Ignacy Nałęcz, Mateusz Zych   +3 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

WallGo investigates: Theoretical uncertainties in the bubble wall velocity

Journal of High Energy Physics
We examine theoretical uncertainties in state-of-the-art calculations of the bubble wall velocity during first-order cosmological phase transitions.
Jorinde van de Vis, Philipp Schicho, Lauri Niemi, Benoit Laurent, Joonas Hirvonen, Oliver Gould   +5 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

A new source of phase transition gravitational waves: heavy particle braking across bubble walls

Journal of High Energy Physics
Motivated by the new heavy dark matter production mechanism from cosmic phase transition, we propose a novel mechanism for the generation of microscopic gravitational waves (GWs) during cosmological first-order phase transitions arising from the braking ...
Dayun Qiu, Siyu Jiang, Fa Peng Huang
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Phase transition and gravitational waves in maximally symmetric composite Higgs model

Journal of High Energy Physics
In this paper we study phase transitions in a maximally symmetric composite Higgs model with next-to-minimal coset, where a pseudoscalar singlet emerges alongside the Higgs doublet.
Avik Banerjee, Marco Merchand, Ignacy Nałęcz   +2 more
doaj   +1 more source