Results 171 to 180 of about 4,768 (180)

A novel glucose sensor fuelling cancer growth. [PDF]

Cell Death Differ
Ricci L, Cardaci S.
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PHB2 Maintains the Contractile Phenotype of VSMCs by Counteracting PKM2 Splicing

Circulation Research, 2022
Background: Phenotypic transition of vascular smooth muscle cells (VSMCs) accounts for the pathogenesis of a variety of vascular diseases during the early stage. Recent studies indicate the metabolic reprogramming may be involved in VSMC phenotypic transition.
Yiting Jia, Chenfeng Mao, Zihan Ma, Jiaqi Huang, Wenqiang Li, Xiaolong Ma, Siting Zhang, Meihong Li, Fang Yu, Yingying Sun, Jingzhou Chen, Juan Feng, Yuan Zhou, Qingbo Xu, Ling Zhao, Yi Fu, Wei Kong   +16 more
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Tetrahydroberberrubine retards heart aging in mice by promoting PHB2-mediated mitophagy

Acta Pharmacologica Sinica, 2022
Heart aging is characterized by left ventricular hypertrophy and diastolic dysfunction, which in turn induces a variety of cardiovascular diseases. There is still no therapeutic drug to ameliorate cardiac abnormities in heart aging. In this study we investigated the protective effects of berberine (BBR) and its derivative tetrahydroberberrubine (THBru)
Lei, Wang, Xue-Qing, Tang, Yang, Shi, Hui-Min, Li, Zi-Yu, Meng, Hui, Chen, Xiao-Han, Li, Yong-Chao, Chen, Heng, Liu, Yang, Hong, Heng-Hui, Xu, Ling, Liu, Limin, Zhao, Wei-Na, Han, Xin, Liu, Yong, Zhang   +15 more
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ASURA (PHB2) Interacts with Scc1 through Chromatin

Cytogenetic and Genome Research, 2013
Sister chromatid cohesion mediated by the cohesin complex is essential for faithful chromosome segregation. Previously we reported that PHB2 (prohibitin2/ASURA), a multifunctional protein, has a role in sister chromatid cohesion. Nevertheless, how ASURA is involved in sister chromatid cohesion still remains unclear.
I, Equilibrina, S, Matsunaga, A, Morimoto, T, Hashimoto, S, Uchiyama, K, Fukui   +5 more
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PHB2 interacts with RNF2 and represses CP2c-stimulated transcription

Molecular and Cellular Biochemistry, 2008
RNF2, a polycomb group protein, is an important component of PRC complex regulating transcriptional activity. Recently, several RNF2 interacting proteins have been identified. Thus, RNF2 might have multiple activities, depending on its interacting partner proteins.
Sun-Joo, Lee, Dongwon, Choi, Hyangshuk, Rhim, Hyo-Jung, Choo, Young-Gyu, Ko, Chul Guen, Kim, Seongman, Kang   +6 more
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The expression of PHB2 in the cochlea: Possible relation to age‐related hearing loss

Cell Biology International, 2021
AbstractAge‐related hearing loss (ARHL) is the most prevalent sensory deficit in the elderly, but its mechanism remains unclear. Scaffold protein prohibitin 2 (PHB2) has been widely involved in aging and neurodegeneration. However, the role of PHB2 in ARHL is undeciphered to date.
Xiaoyu Yu, Ming Guan, Haiqiong Shang, Yaoshu Teng, Yueqiu Gao, Bin Wang, Zhiqi Ma, Xiaolin Cao, Yong Li   +8 more
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Study on the Role of Mitophagy Receptor PHB2 in Doubly Uniparental Inheritance of Hyriopsis cumingii

Marine Biotechnology, 2023
In bivalves, the heterogeneity of mitochondrial DNA and its unique mode of transmission have been the focus of attention, which is called doubly uniparental inheritance (DUI). Prohibitin-2 (phb2) is a mitochondrial inner membrane protein that is a key mitophagy receptor for parental mitochondrial removal.
Yayu, Wang, Xiaoyue, Zhu, Yang, Gu, Zongyu, Liu, Yingrui, Mao, Xiaojun, Liu, Zhiyi, Bai, Guiling, Wang, Jiale, Li   +8 more
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PHB2 inhibits WSSV replication by promoting the nuclear translocation of STAT

Fish & Shellfish Immunology
Prohibitins (PHBs) are ubiquitously expressed conserved proteins in eukaryotes that are associated with apoptosis, cancer formation, aging, stress responses and cell proliferation. However, the function of the PHBs in immune regulation has largely not been determined.
Jia-Yu, Si, Lian-Jie, Wu, Feng-Lin, Xu, Xiao-Tong, Cao, Jiang-Feng, Lan   +4 more
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PHB2 Governs Metabolism and Phenotypic Switching of VSMCs in Vascular Remodeling

Circulation Research, 2022
Kathy O. Lui, Yu Huang
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HBV_circ_1 Promotes Hepatocellular Carcinoma Progression via Blocking PHB2-Mediated Mitophagy

2023
Zi Liang, Min Zhu, Ji Wang, Lei Qin, Jun Pan, Xing Zhang, Xiaolong Hu, Chenliang Gong   +7 more
openaire   +1 more source