Results 171 to 180 of about 9,767 (219)
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Phenacetin nephritis

Urology, 1975
Prolonged ingestion of mixed analgesics containing phenacetin has been associated significantly with the development of a chronic interstitial nephritis frequently associated with papillary necrosis. This disease is frequently underdiagnosed. If an adequate history of headache and/or backache (of which most of these patients complain) is not taken, the
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Sterility From Phenacetin

The Journal of Clinical Pharmacology and New Drugs, 1971
Daily administration of .29 gm/kg per day phenacetin to male albino rats for 220 days had no effect on body weight food and water intake colonic temperature and the volume or composition of urine. Then were no deaths and no evidence of pathologological lesions in the liver or kidneys or increased susceptibility to infections.
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Phenacetin: an update

Journal of Endodontics, 1979
Phenacetin, or its derivative acetaminophen, is an extremely common and increasingly used substitute for aspirin. Although the drug is mild and effective, its toxicity is less obvious and less manageable than that of aspirin.
G F, Valle   +2 more
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Paracetamol and Phenacetin

Drugs, 1986
Since their synthesis in the late 1800s paracetamol (acetaminophen) and phenacetin have followed divergent pathways with regard to their popularity as mild analgesic/antipyretic drugs. Initially, paracetamol was discarded in favour of phenacetin because the latter drug was supposedly less toxic.
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THE PHENACETIN ENIGMA

Journal of the American Geriatrics Society, 1970
A bstract The unregulated sale of phenacetin‐containing anodynes frequently has led to abuse of this drug by consumers. The demonstration of renal papillary necrosis in persons who habitually use excessive amounts (3.5 kg or more as the cumulative lifetime dose) has been ...
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Phenacetin Safety

Science, 1980
A W, Macklin, R M, Welch
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