Results 181 to 190 of about 5,776 (241)

Collective Total Syntheses of Benzo[c]phenanthridine Alkaloids via a Sequential Transition Metal-Catalyzed Pot-Economic Approach.

Organic Letters, 2022
Collective total syntheses of 10 benzo[c]phenanthridines were achieved on the basis of the construction of rings C and B through sequential transition metal-catalyzed reactions and flexible condition-controlled Mannich reaction via three pots in 25-34 ...
Jiayue Fu, Bing-Qian Li, Xinxiu Wang, He Wang, Ming-zhuo Deng, Hua-Li Yang, B. Lin, Maosheng Cheng, Lu Yang, Yongxian Liu   +9 more
semanticscholar   +1 more source

Selective Synthesis of Dihydrophenanthridine and Phenanthridine Derivatives from the Cascade Reactions of o-Arylanilines with Alkynoates through C-H/N-H/C-C Bond Cleavage.

Journal of Organic Chemistry, 2021
In this paper, an unprecedented selective synthesis of dihydrophenanthridine and phenanthridine derivatives through the cascade reactions of 2-arylanilines with alkynoates is presented.
Yuanshuang Xu, Caiyun Yu, Xinying Zhang, Xuesen Fan   +3 more
semanticscholar   +1 more source

Antimalarial benzo[c]phenanthridines

Bioorganic & Medicinal Chemistry Letters, 2005
Analogues of the antimalarial alkaloid nitidine have been prepared with high potency against both chloroquine-sensitive and -resistant strains of Plasmodium falciparum in vitro. Simple modifications, using an established synthetic route, resulted in an analogue with IC(50) below 5ng/mL against a chloroquine-sensitive strain of P. falciparum.
James M, Nyangulu, Samantha L, Hargreaves, Susan L, Sharples, Simon P, Mackay, Roger D, Waigh, Olivier, Duval, Eddie K, Mberu, William M, Watkins   +7 more
openaire   +2 more sources

Efficient extraction and purification of benzo[c]phenanthridine alkaloids from Macleaya cordata (Willd) R. Br. by combination of ultrahigh pressure extraction and pH-zone-refining counter-current chromatography with anti-breast cancer activity in vitro.

Phytochemical Analysis, 2020
INTRODUCTION Macleaya cordata (Willd) R. Br. (Papaveraceae family) is a well-known traditional Chinese medicine used to treat muscle pain, inflamed wounds, and bee bites. Benzo[c]phenanthridine alkaloids are the main active ingredients in M. cordata.
Iftikhar Ali, Jingchao Li, Li Cui, Hongwei Zhao, Qiuxia He, Daijie Wang   +5 more
semanticscholar   +1 more source

Fluorescent chemosensor for Hg2+ ions based on pyridine attached phenanthridine probe

New Journal of Chemistry, 2021
A ratiomeric fluorescence phenanthridine sensor (4), functionalised with pyridine moiety, has been prepared. Sensor 4 displayed both fluorescence and absorbance changes for the selective recognition of Hg2+ ions in acetonitrile/water...
Shanthi Seenan, S. Manickam, Sathiyanarayanan Kulathu Iyer   +2 more
semanticscholar   +1 more source

A Review on Synthetic Approaches of Phenanthridine

, 2021
The phenanthridine family is widely found in medicinal chemistry and material science because of the biological activity and the presence in a variety of significant natural products and synthetic dye-stuffs.
Nilesh Kshirsagar, Ratnamala P. Sonawane, S. Pathan, G. Kamble, G. Singh   +4 more
semanticscholar   +1 more source

Phenanthridines

ChemInform, 2005
AbstractFor Abstract see ChemInform Abstract in Full Text.
openaire   +1 more source

Phenanthridine-based Covalent Organic Frameworks for Boosting Overall Solar H2O2 Production.

Angewandte Chemie
Solar-driven H2O2 production via the oxygen reduction reaction (ORR) and water oxidation reaction (WOR) dual channels is green and sustainable, but severely restricted by the sluggish reaction kinetics.
Jie‐Yu Yue, Jing-Xian Luo, Zi‐Xian Pan, Qing Xu, Peng Yang, Bo Tang   +5 more
semanticscholar   +1 more source

Phenanthridine derivatives as promising new anticancer agents: synthesis, biological evaluation and binding studies.

Future Medicinal Chemistry, 2020
Aim: Phenanthridines are an essential class of nitrogenous heterocycles with extensive applications in medicinal chemistry. The development of efficient and eco-friendly methods for the preparation of chirally pure dihydropyrrolo[1,2-f]phenanthridines ...
Iqbal Azad, R. Ahmad, Tahmeena Khan, M. Saquib, F. Hassan, Y. Akhter, AbdulR. Khan, M. Nasibullah   +7 more
semanticscholar   +1 more source

Phenanthridine alkaloids from Zanthoxylum madagascariense

Fitoterapia, 2005
Four benzo[c]phenanthridine alkaloids have been isolated from the stem bark of Zanthoxylum madagascariense. These compounds were identified by extensive use of NMR spectroscopy.
M T, Martin, L H, Rasoanaivo, A, Raharisololalao   +2 more
openaire   +2 more sources