Results 71 to 80 of about 5,776 (241)

Ortho Arylation of N‐Aryl Amides and the Construction of Diagonal Tetraarylbenzenediamines and N‐Doped Fulminenes via BBr3‐Derived Dibromoboracycles

open access: yesChemistry – A European Journal, Volume 31, Issue 8, February 6, 2025.
We report the discovery of a boron‐driven ortho‐arylation reaction of N‐aryl amides and ureas. This novel method enables directed borylation of a wide range of substrates, leading to the synthesis of unique compounds such as N‐doped fulminene and diagonal tetraarylbenzenediamines.
Ganesh H. Shinde   +2 more
wiley   +1 more source

Safety assessment of sanguiritrin, alkaloid fraction of Macleaya cordata, in rats

open access: yesVeterinární Medicína, 2006
The subchronic safety of sanguiritrin, a mixture of sanguinarine (SA) and chelerythrine (CHE) quaternary benzo[c]phenanthridine alkaloids (QBA), obtained from Macleaya cordata was assessed.
J. Psotova   +12 more
doaj   +1 more source

New 2-aryl-7,8-dimethoxy-3,4-dihydroisoquinolin-2-ium salts as potential antifungal agents: synthesis, bioactivity and structure-activity relationships

open access: yesScientific Reports, 2017
The title compounds can be considered as simple analogues of quaternary benzo[c]phenanthridine alkaloids (QBAs). In order to develop potent QBA-like antifungal agents, as our continuing study, a series of new title compounds were synthesized and ...
Lifei Zhu   +5 more
doaj   +1 more source

Chelerythrine Attenuates the Inflammation of Lipopolysaccharide-Induced Acute Lung Inflammation Through NF-κB Signaling Pathway Mediated by Nrf2

open access: yesFrontiers in Pharmacology, 2018
Chelerythrine (CH), is a kind of benzo[c] phenanthridine alkaloid isolated from plants such as Chelidonium, with pharmacological activities as antitumor, antibiosis and anti-inflammation.
Lu Fan   +9 more
doaj   +1 more source

The effect of geometric isomerism on the anticancer activity of the monofunctional platinum complex trans-[Pt(NH3)2(phenanthridine)Cl]NO3.

open access: yesChemical Communications, 2018
A trans-DDP based monofunctional phenanthridine Pt(ii) complex was synthesized and characterized. Its anticancer activity was studied in vitro on a panel of human cancer cell lines and mouse intestinal cancer organoids.
Wen Zhou   +5 more
semanticscholar   +1 more source

A phenanthrene derived PARP inhibitor is an extra-centrosomes de-clustering agent exclusively eradicating human cancer cells

open access: yesBMC Cancer, 2011
Background Cells of most human cancers have supernumerary centrosomes. To enable an accurate chromosome segregation and cell division, these cells developed a yet unresolved molecular mechanism, clustering their extra centrosomes at two poles, thereby ...
Izraeli Shai   +5 more
doaj   +1 more source

Seasonal Variation of Bioactive Alkaloid Contents in Macleaya microcarpa (Maxim.) Fedde

open access: yesMolecules, 2011
Macleaya microcarpa (Maxim.) Fedde belongs to the genus Macleaya, family Papaveraceae. Together with the better known and more frequently studied species M. cordata (Willd.) R. Br. it is a main source of quaternary benzo[c]phenanthridine alkaloids. Using
Jana Gregorová   +4 more
doaj   +1 more source

Ueber Phenanthridin [PDF]

open access: yesBerichte der deutschen chemischen Gesellschaft, 1889
Pictet, Amé, Ankersmit, H. Jan
openaire   +2 more sources

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