Results 71 to 80 of about 30,843 (202)
Transcriptional changes common to human cocaine, cannabis and phencyclidine abuse.
PLoS ONE, 2006 A major goal of drug abuse research is to identify and understand drug-induced changes in brain function that are common to many or all drugs of abuse. As these may underlie drug dependence and addiction, the purpose of the present study was to examine ...
Elin Lehrmann +8 more
doaj +1 more source
Medicina, 2019 Background and Objectives: Previously we have shown that synthetic lunasin, a 43 amino acid residue-containing peptide, after its central (intracisternal) administration in mice demonstrated antagonism against dopaminergic drug behavioural effects ...
Zane Dzirkale +4 more
doaj +1 more source
Schizophrenia is a TH2 dominant autoimmune disease possibly against acetylcholine receptors of CNS [PDF]
, 2012 Schizophrenia is a very common psychiatric disorder. However, its etiology and pathogenesis is still unknown. Current theory saying that neurotransmitter imbalance such as serotonin or dopamine only provides limited effectiveness in schizophrenia ...
Wanchung(Wan-Jiung) Hu
core +1 more source
Combined NMDA Inhibitor Use in a Patient With Multisubstance-induced Psychotic Disorder [PDF]
, 2018 This document is an Accepted Manuscript reprinted from Journal of Addiction Medicine, Vol. 12 (3): 247-251, May 2018, with permission of Kluwer Law International. Under embargo until 1 May 2019.
Calabrò, Giuseppa +9 more
core +2 more sources
BMC Pharmacology and Toxicology, 2017 Background The presentation of schizophrenia (SCH) symptoms differs between the sexes. Long-term treatment with antipsychotics is frequently associated with decreased bone mineral density, increased fracture risk and metabolic side effects.
Tatjana Nikolić +8 more
doaj +1 more source
Glutamatergic-dopaminergic balance in the brain. Its importance in motor disorders and schizophrenia [PDF]
, 1992 Dopamine appears to be of less importance in the regulation of psychomotor functions than was previously thought. A central dopaminergic-glutamatergic balance may be important for both akinetic motor disorders and psychosis.
Danielczyk, W. +3 more
core
Bali Journal of Anesthesiology, 2017 Ketamine binds non-competitive against a phencyclidine receptors bound N-methyl-D-aspartate (NMDA), a receptor that is involved in the pathophysiology of acute pain.
Made Wiryana +10 more
doaj +1 more source
The Role of Parvalbumin-positive Interneurons in Auditory Steady-State Response Deficits in Schizophrenia [PDF]
, 2019 © The Author(s) 2019. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the ...
A.M. Lavoie +45 more
core +2 more sources
Altered excitatory-inhibitory balance in the NMDA-hypofunction model of schizophrenia
Frontiers in Molecular Neuroscience, 2008 Schizophrenia is a common psychiatric disorder of high incidence, affecting approximately 1% of the world population. The essential neurotransmitter pathology of schizophrenia remains poorly defined, despite huge advances over the past half-century in ...
Colin Kehrer +3 more
doaj +1 more source
Role of Thalamic Projection in NMDA Receptor-Induced Disruption of Cortical Slow Oscillation and Short-Term Plasticity [PDF]
, 2011 NMDA receptor (NMDAR) antagonists, such as phencyclidine, ketamine or dizocilpine (MK-801) are commonly used in psychiatric drug discovery in order to model several symptoms of schizophrenia, including psychosis and impairments in working memory.
Tamás Kiss +6 more
core +2 more sources