Results 51 to 60 of about 30,843 (202)

Identification of developmentally regulated PCP-responsive non-coding RNA, prt6, in the rat thalamus. [PDF]

PLoS ONE, 2014
Schizophrenia and similar psychoses induced by NMDA-type glutamate receptor antagonists, such as phencyclidine (PCP) and ketamine, usually develop after adolescence.
Hironao Takebayashi, Naoki Yamamoto, Asami Umino, Toru Nishikawa   +3 more
doaj   +1 more source

Effects of Antipsychotics on the Hypothalamus–Pituitary–Adrenal Axis in a Phencyclidine Animal Model of Schizophrenia

Cells
Schizophrenia (SCH) is a mental disorder that requires long-term antipsychotic treatment. SCH patients are thought to have an increased sensitivity to stress.
Tatjana Nikolić, Milica Velimirović Bogosavljević, Tihomir Stojković, Selma Kanazir, Nataša Lončarević-Vasiljković, Nevena V. Radonjić, Jelena Popić, Nataša Petronijević   +7 more
doaj   +1 more source

Recurrent deletions of ULK4 in schizophrenia : a gene crucial for neuritogenesis and neuronal motility [PDF]

, 2013
Peer reviewedPublisher ...
Blackwood, Douglas H, Gao, Guo-Dong, Guan, Zhen-Long, He, Guang, He, Lin, Hunter, Irene, Lang, Bing, Li, Wei-Dong, Liu, Min, Martin-Granados, Christina, McCaig, Colin D, Pu, Jin, Reilly, Thomas J, Shen, Sanbing, Shi, Yong-Yong, St Clair, David, Stefansson, Hreinn   +16 more
core   +1 more source

The Effect of Phencyclidine New Derivatives on Anxiety Behaviors in Rats [PDF]

Iranian Journal of Basic Medical Sciences, 2010
Objective(s) Anxiety is a common disorder which afflicts many people in any society and is often accompanied by physiological sensations such as tachycardia, chest pain, shortness of breath, insensitivity, etc.
Ramin Hajkhani, Jalal Solati, Abbas Ahmadi, Ali-Akbar Salari   +3 more
doaj  

Phencyclidine: A rare cause of saccadic intrusions

Annals of Indian Academy of Neurology, 2019
Saccadic intrusions such as opsoclonus and ocular flutter are often due to a paraneoplastic or a parainfectious condition. Toxins/drugs may rarely cause them. Herein, we report a rare case of ocular flutter/opsoclonus due to phencyclidine (PCP) toxicity.
M N Shameer Nijam, Narmathey Thambirajah, Dhanushka Vithanawasam, Kumarangie Vithanage, Damith S Liyanage, I Kishara Gooneratne, Sunethra Senanayake   +6 more
doaj   +1 more source

Effects of asenapine, olanzapine, and risperidone on psychotomimetic-induced reversal-learning deficits in the rat [PDF]

, 2010
YesBackground: Asenapine is a new pharmacological agent for the acute treatment of schizophrenia and bipolar disorder. It has relatively higher affinity for serotonergic and α2-adrenergic than dopaminergic D2 receptors.
Abdul-Monim, Abdul-Monim, Abdul-Monim, Addington, Aghajanian, Amargos-Bosch, Anand, Bilder, Cuesta, Depoortere, Didriksen, Drake, Erik H.F. Wong, Fleischhaker, Fleming, Franberg, Goldberg, Gray, Grayson, Green, Harvey, Hatcher, Hirst, Huang, Hugh M. Marston, Idris, Idris, Jentsch, Jentsch, Jentsch, Jentsch, Jo C. Neill, Jones, Kapur, Keefe, Krystal, Lewis, Marcus, Marston, Martin, McIntyre, McLean, McLean, McLean, Mohammed Shahid, Nagi F. Idris, Neill, Olney, O’Grada, Potkin, Samantha L. McLean, Schmidt, Schotte, Shahid, Smith, Snigdha, Sutcliffe, Sutcliffe, Tait, Tarazi, Tarazi, Terranova, Wolff   +62 more
core   +1 more source

Clozapine and haloperidol differently suppress the MK-801-increased glutamatergic and serotonergic transmission in the medial prefrontal cortex of the rat [PDF]

, 2007
The administration of noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonists such as phencyclidine and ketamine has been shown to increase the extracellular concentration of glutamate and serotonin (5-HT) in the medial prefrontal cortex (mPFC ...
López-Gil, Xavier, Babot, Zoila, Amargós-Bosch, Mercè, Suñol, Cristina, Artigas, Francesc, Adell, Albert   +5 more
core   +1 more source

Using molecular similarity to highlight the challenges of routine immunoassay-based drug of abuse/toxicology screening in emergency medicine

BMC Emergency Medicine, 2009
Background Laboratory tests for routine drug of abuse and toxicology (DOA/Tox) screening, often used in emergency medicine, generally utilize antibody-based tests (immunoassays) to detect classes of drugs such as amphetamines, barbiturates ...
Siam Mohamed G, Pizon Anthony F, Krasowski Matthew D, Giannoutsos Spiros, Iyer Manisha, Ekins Sean   +5 more
doaj   +1 more source

Parvalbumin promoter hypermethylation in postmortem brain in schizophrenia [PDF]

, 2018
Deficits of brain parvalbumin (PV) are a consistent finding in schizophrenia and models of psychosis. We investigated whether this is associated with abnormal PV gene (PVALB) methylation in the brain in schizophrenia. Bisulfite pyrosequencing was used to
Caroline F Dalton, Gavin P Reynolds, Helene A Fachim, Kinoshita M, Umarat Srisawat   +4 more
core   +1 more source

Les psychotropes criminogènes [PDF]

, 2007
Les psychotropes altèrent le psychisme d’un individu et peuvent affecter les perceptions, l’humeur, la conscience, le comportement et diverses fonctions psychologiques et physiques.
Ben Amar, Mohamed
core   +1 more source