Results 61 to 70 of about 23,005 (222)

False-Positive Phencyclidine (PCP) Result on 11-Panel Urine Drug Screen (UDS) in a 17-Year-Old Adolescent with Long-Term Venlafaxine Use

Case Reports in Psychiatry, 2023
Venlafaxine is an antidepressant belonging to the class of serotonin–norepinephrine reuptake inhibitors that are US Food and Drug Administration-approved to treat and manage symptoms of depression, anxiety, and other mood disorders in adults. We describe
Hyun Sue Kim, Aakash Jain, Anita S. Kablinger   +2 more
doaj   +1 more source

Effects of Antipsychotics on the Hypothalamus–Pituitary–Adrenal Axis in a Phencyclidine Animal Model of Schizophrenia

Cells
Schizophrenia (SCH) is a mental disorder that requires long-term antipsychotic treatment. SCH patients are thought to have an increased sensitivity to stress.
Tatjana Nikolić, Milica Velimirović Bogosavljević, Tihomir Stojković, Selma Kanazir, Nataša Lončarević-Vasiljković, Nevena V. Radonjić, Jelena Popić, Nataša Petronijević   +7 more
doaj   +1 more source

: Effect of sub‐chronic phencyclidine pretreatment

, 2021
Dopamine signaling in nucleus accumbens (NAc) is modulated by gamma-aminobutyric acid (GABA), acting through GABA-A and GABA-B receptors: dysregulation of GABAergic control of dopamine function may be important in behavioral deficits in schizophrenia. We
Jacqueline‐Marie Ferdinand, Andrew M. J. Young, Ersin Yavas, Yavaş, Ersin, Kate Z. Peters, Ferdinand, Jacqueline-Marie, Young, Andrew M. J., Peters, Kate Z.   +7 more
core   +1 more source

The Effect of Phencyclidine New Derivatives on Anxiety Behaviors in Rats [PDF]

Iranian Journal of Basic Medical Sciences, 2010
Objective(s) Anxiety is a common disorder which afflicts many people in any society and is often accompanied by physiological sensations such as tachycardia, chest pain, shortness of breath, insensitivity, etc.
Ramin Hajkhani, Jalal Solati, Abbas Ahmadi, Ali-Akbar Salari   +3 more
doaj  

Phencyclidine: A rare cause of saccadic intrusions

Annals of Indian Academy of Neurology, 2019
Saccadic intrusions such as opsoclonus and ocular flutter are often due to a paraneoplastic or a parainfectious condition. Toxins/drugs may rarely cause them. Herein, we report a rare case of ocular flutter/opsoclonus due to phencyclidine (PCP) toxicity.
M N Shameer Nijam, Narmathey Thambirajah, Dhanushka Vithanawasam, Kumarangie Vithanage, Damith S Liyanage, I Kishara Gooneratne, Sunethra Senanayake   +6 more
doaj   +1 more source

Identification of developmentally regulated PCP-responsive non-coding RNA, prt6, in the rat thalamus. [PDF]

PLoS ONE, 2014
Schizophrenia and similar psychoses induced by NMDA-type glutamate receptor antagonists, such as phencyclidine (PCP) and ketamine, usually develop after adolescence.
Hironao Takebayashi, Naoki Yamamoto, Asami Umino, Toru Nishikawa   +3 more
doaj   +1 more source

Discriminative stimulus effects of N-substituted analogs of phencyclidine in rhesus monkeys [PDF]

, 1982
In daily sessions of a two-lever, discrete-trial, food-reinforced procedure, rhesus monkeys were trained to discriminate between subcutaneous injections of ketamine (1.0 or 1.8 mg/kg) and control injections.
Solomon, Robert E., Domino, Edward F., Woods, James H., Herling, Seymore   +3 more
core   +1 more source

Opioid Properties of Some Isomeric Derivatives of Phencyclidine

, 1992
The phencyclidine analogues (±)-α-, (±)-β-, and (+)-α- and (–)-α-4-hydroxy-3-methyl-4-phenyl-l-(1-phenylcyclohexyl)piperidine, all with known relative and absolute stereochemistry, have been prepared, and their analgesic potencies related to ...
A F Casy, O A A Al-Deeb, G H Dewar
core   +1 more source

Using molecular similarity to highlight the challenges of routine immunoassay-based drug of abuse/toxicology screening in emergency medicine

BMC Emergency Medicine, 2009
Background Laboratory tests for routine drug of abuse and toxicology (DOA/Tox) screening, often used in emergency medicine, generally utilize antibody-based tests (immunoassays) to detect classes of drugs such as amphetamines, barbiturates ...
Siam Mohamed G, Pizon Anthony F, Krasowski Matthew D, Giannoutsos Spiros, Iyer Manisha, Ekins Sean   +5 more
doaj   +1 more source

Chemical structures of ketamine, methoxetamine, phencyclidine and analogues.

, 2013
Chemical structures of ketamine, methoxetamine, phencyclidine and analogues.
Warunya Arunotayanun (391869), Les Iversen (391873), Xi-Ping Huang (391870), Vincent Setola (391871), Simon Gibbons (391868), Ric Treble (391872), Bryan L. Roth (143613)   +6 more
core   +1 more source