Results 81 to 90 of about 30,643 (283)

Ocular sequelae from the illicit use of class A drugs [PDF]

, 2004
Aim: To highlight the changes that may take place in the visual system of the class A drug abuser. Methods: A literature review was carried out of ocular/visual sequelae of the more common class A drugs.
Firth, A.Y.
core  

Unraveling monoamine receptors involved in the action of typical and atypical antipsychotics on glutamatergic and serotonergic transmission in prefrontal cortex [PDF]

, 2013
El pdf del artículo es la versión post-print.The systemic administration of noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonists has been considered as a pharmacological model of schizophrenia.
Adell, Albert, Artigas, Francesc, López-Gil, Xavier   +2 more
core   +2 more sources

Hyperactivity of Endoplasmic Reticulum Associated Exocytosis Mechanism Contributes to Acute Phencyclidine Intoxication

Journal of Pharmacological Sciences, 2004
Phencyclidine (PCP) produces schizophrenia-like psychosis and acute PCP-intoxications; however, whether glutamate/NMDA-receptor blockade by PCP modulates or not these mechanisms has remained to be clarified.
Gang Zhu, Motohiro Okada, Daishi Uchiyama, Tadashi Ohkubo, Shukuko Yoshida, Sunao Kaneko   +5 more
doaj   +1 more source

D1-like receptor activation improves PCP-induced cognitive deficits in animal models: Implications for mechanisms of improved cognitive function in schizophrenia [PDF]

, 2009
YesPhencyclidine (PCP) produces cognitive deficits of relevance to schizophrenia in animal models. The aim was to investigate the efficacy of the D1-like receptor agonist, SKF-38393, to improve PCPinduced deficits in the novel object recognition (NOR ...
Abdul-Monim, Abdul-Monim, Abdul-Monim, Amico, Apud, Arnsten, Benes, Benes, Briggs, Brown, Buchanan, Cahill, Castner, Ciliax, Creese, Davis, Dawson, Finger, Fletcher, Fletcher, George, Goldman-Rakic, Goldman-Rakic, Grace, Granon, Gray, Grayson, Grayson, Green, Guillin, Hagan, Hagger, Harvey, Haut, Hersi, Hirvonen, Ichikawa, Idris, Javitt, Jentsch, Jentsch, Jentsch, Joanna C. Neill, Kashima, Kebabian, Keefe, Kolb, Lahti, Lawler, Levey, Lidow, Lieberman, Marder, Marie L. Woolley, McAlonan, McLean, McLean, Meador-Woodruff, Meltzer, Meunier, Mu, Murray, Nagi F. Idris, Neill, Neill, Neumeyer, Okubo, Pantelis, Qandil, Rossi, Samantha L. McLean, Sawaguchi, Seeman, Siuciak, Snigdha, Snigdha, Snigdha, Snigdha, Spano, Steele, Sutcliffe, Sutcliffe, Tait, Tunbridge, Vincent   +84 more
core   +1 more source

Mechanistic Insights Into Photocatalytic Materials for Toxic Pollutants: Environmental Remediation of Personal Care Products

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT Photocatalytic materials have emerged as promising solutions for environmental applications due to their ability to degrade organic pollutants under sunlight or artificial light. In this review, recent progress on the photocatalytic materials used for the degradation of pharmaceutical personal care products (PPCPs) in environmental ...
Urvashi Sen, Gunjan Chauhan, Surbhi Soni, Monika Vats, Anand Kumar, Indra Bahadur   +5 more
wiley   +1 more source

Identification of a New Psychoactive Substances of Phencyclidine-type, 2-Oxo-PCPr in Seized e-Cigarette Oil

Zhipu Xuebao
The new psychoactive substances (NPSs) are defined as a category of substances of abuse, either in a pure form or a preparation, that are not listed in the control table by the 1961 Single Convention on Narcotic Drugs or the 1971 Convention on ...
Jia-lei WU, Qiang ZHANG, Xue-hu WANG, Ling-yun LIU, Li-qi CHEN, Rui-hua WANG, Fang-min XU   +6 more
doaj   +1 more source

Comparison of the efficacy of two anticonvulsants, phenytoin and valproate to improve PCP and d-amphetamine induced deficits in a reversal learning task in the rat

Frontiers in Behavioral Neuroscience, 2009
Recent studies in our laboratory have shown that PCP (phencyclidine) and d-amphetamine induce a cognitive deficit in rats, in a paradigm of potential relevance for the pathology of schizophrenia.
Nagi F Idris, JO C Neill, Charles H Large   +2 more
doaj   +1 more source

5‐Methylcytosine Analysis of miRNAs in Minimal Change Disease

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Minimal change disease (MCD) is a glomerular disorder, which is the most common cause of nephrotic syndrome in children. Additionally, the prevalence of MCD in adults has been increasing in recent years. During protein synthesis, noncoding RNAs can be regulated through a variety of modifications, which helps preserve biological diversity and ...
Huiyi Zeng, Dandan Li, Yunyi Li, Chen Yun, Xinzhou Zhang, Wenyu Gong, Mengyun Xiao, Haitao Li, Zhipeng Zeng, Ruqi Tan, Yishen Yang, Shaodong Luan, Yong Dai, Lianghong Yin, Donge Tang   +14 more
wiley   +1 more source

Inducible nitric oxide inhibitors block NMDA antagonist-stimulated motoric behaviors and medial prefrontal cortical glutamate efflux

Frontiers in Pharmacology, 2015
Nitric oxide (NO) plays a critical role in the motoric and glutamate releasing action of N-methyl-D-aspartate (NMDA)-antagonist stimulants. Earlier studies utilized neuronal nitric oxide synthase inhibitors (nNOS) for studying the neurobehavioral effects
Hadley C Bergstrom, Altaf eDavesh, Altaf eDavesh, S Paul Berger   +3 more
doaj   +1 more source

Clozapine reverses phencyclidine-induced desynchronization of prefrontal cortex through a 5-HT 1A receptor-dependent mechanism [PDF]

, 2013
The non-competitive NMDA receptor (NMDA-R) antagonist phencyclidine (PCP) - used as a pharmacological model of schizophrenia - disrupts prefrontal cortex (PFC) activity.
Artigas, Francesc, Celada, Pau, Kargieman, Lucila, Riga, Maurizio   +3 more
core   +1 more source