Results 11 to 20 of about 10,621 (203)

Health disparities in chronic liver disease

open access: yesHepatology, EarlyView., 2022
Abstract The syndemic of hazardous alcohol consumption, opioid use, and obesity has led to important changes in liver disease epidemiology that have exacerbated health disparities. Health disparities occur when plausibly avoidable health differences are experienced by socially disadvantaged populations.
Ani Kardashian   +3 more
wiley   +1 more source

Sex and Gender Differences in the Effects of Novel Psychoactive Substances

open access: yesBrain Sciences, 2020
Sex and gender deeply affect the subjective effects and pharmaco-toxicological responses to drugs. Men are more likely than women to use almost all types of illicit drugs and to present to emergency departments for serious or fatal intoxications. However,
Liana Fattore   +3 more
doaj   +1 more source

Ketamine: NMDA receptors and beyond [PDF]

open access: yes, 2016
Human studies examining the effects of the dissociative anesthetic ketamine as a model for psychosis and as a rapidly acting antidepressant have spurred great interest in understanding ketamine's actions at molecular, cellular, and network levels ...
Izumi, Yukitoshi   +2 more
core   +2 more sources

From "Special K" to "Special M" : The Evolution of the Recreational use of Ketamine and Methoxetamine [PDF]

open access: yes, 2013
Objective: To review the recreational use of ketamine (‘Special K’; KET) and explore the recent diffusion of its new derivative methoxetamine (‘Special M’; MXE).
Assi, Sulaf   +2 more
core   +1 more source

Recreational use, analysis and toxicity of tryptamines [PDF]

open access: yes, 2015
The definition New psychoactive substances (NPS) refers to emerging drugs whose chemical structures are similar to other psychoactive compounds but not identical, representing a "legal" alternative to internationally controlled drugs.
Mannocchi, Giulio   +3 more
core   +1 more source

Using molecular similarity to highlight the challenges of routine immunoassay-based drug of abuse/toxicology screening in emergency medicine

open access: yesBMC Emergency Medicine, 2009
Background Laboratory tests for routine drug of abuse and toxicology (DOA/Tox) screening, often used in emergency medicine, generally utilize antibody-based tests (immunoassays) to detect classes of drugs such as amphetamines, barbiturates ...
Siam Mohamed G   +5 more
doaj   +1 more source

Recent changes in drug abuse scenarios : The new/novel psychoactive substances (NPS) phenomenon [PDF]

open access: yes, 2018
© 2018 by the author. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).Peer ...
Schifano, Fabrizio
core   +2 more sources

Ketamine-Based Anesthetic Protocols and Evoked Potential Monitoring: A Risk/Benefit Overview

open access: yesFrontiers in Neuroscience, 2016
Since its discovery, ketamine, a noncompetitive N-methyl D-aspartate (NMDA) receptor antagonist related to phencyclidine, has been linked to multiple adverse reactions sometimes described as out of body and near death experiences, including emergence ...
Nicoleta eStoicea   +8 more
doaj   +1 more source

The effects of memantine on prepulse inhibition. [PDF]

open access: yes, 2009
Reduced prepulse inhibition (PPI) of startle provides evidence of deficient sensorimotor gating in several disorders, including schizophrenia. The role of NMDA neurotransmission in the regulation of PPI is unclear, due to cross-species differences in the
Bergsma, F   +4 more
core   +2 more sources

Increased DNA methylation in the parvalbumin gene promoter is associated with methamphetamine dependence [PDF]

open access: yes, 2017
Aim: The parvalbumin (PV)-containing subgroup of GABAergic neurons is particularly affected in schizophrenia and animal models of psychosis, including after methamphetamine (METH) administration.
Dalton, Caroline   +6 more
core   +1 more source

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