The Cost Effectiveness of Psychological and Pharmacological Interventions for Social Anxiety Disorder: A Model-Based Economic Analysis. [PDF]
PLoS ONE, 2015 BackgroundSocial anxiety disorder is one of the most persistent and common anxiety disorders. Individually delivered psychological therapies are the most effective treatment options for adults with social anxiety disorder, but they are associated with ...
Ifigeneia Mavranezouli +6 more
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Metabolic Effects of Oral Phenelzine Treatment on High-Sucrose-Drinking Mice [PDF]
International Journal of Molecular Sciences, 2018 Phenelzine has been suggested to have an antiobesity effect by inhibiting de novo lipogenesis, which led us to investigate the metabolic effects of oral chronic phenelzine treatment in high-sucrose-drinking mice.
C. Carpéné +3 more
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A Case of the Serotonin Syndrome Secondary to Phenelzine Monotherapy at Therapeutic Dosing
Case Reports in Medicine, 2015 A 27-year-old Caucasian female with a history of depression was admitted to our local hospital with vague events that occurred a day before. This included an episode of dysarthria, and unsteadiness, followed by feeling generally unwell.
A. Malik, N. Junglee
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Comparative Examination of Moclobemide, Tranylcypromine, Phenelzine and Isocarboxazid for Monoamine Oxidase–A Inhibition [PDF]
Advanced Journal of Chemistry Section B, 2019 The ligand–receptor complex formations between the monoamine oxidase–A (MAO–A) enzyme and its known inhibitors have been examined based on the in silico approach.
Zahra S. Alidoosti, Mahmoud Mirzaei
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Continuous Infusion of Phenelzine, Cyclosporine A, or Their Combination: Evaluation of Mitochondrial Bioenergetics, Oxidative Damage, and Cytoskeletal Degradation following Severe Controlled Cortical Impact Traumatic Brain Injury in Rats [PDF]
Journal of Neurotrauma, 2018 To date, all monotherapy clinical traumatic brain injury (TBI) trials have failed, and there are currently no Food and Drug Administration (FDA)–approved pharmacotherapies for the acute treatment of severe TBI. Due to the complex secondary injury cascade
Jacqueline R. Kulbe +4 more
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PCLAF-DREAM drives alveolar cell plasticity for lung regeneration [PDF]
Nature CommunicationsCell plasticity, changes in cell fate, is crucial for tissue regeneration. In the lung, failure of regeneration leads to diseases, including fibrosis. However, the mechanisms governing alveolar cell plasticity during lung repair remain elusive.
Bongjun Kim +14 more
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Biomarker-driven drug repurposing for NAFLD-associated hepatocellular carcinoma using machine learning integrated ensemble feature selection [PDF]
Frontiers in BioinformaticsThe incidence of non-alcoholic fatty liver disease (NAFLD), encompassing the more severe non-alcoholic steatohepatitis (NASH), is rising alongside the surges in diabetes and obesity.
Subhajit Ghosh +2 more
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Neuroprotection by acrolein sequestration through exogenously applied scavengers and endogenous enzymatic enabling strategies in mouse EAE model [PDF]
Scientific ReportsWe have previously shown that the pro-oxidative aldehyde acrolein is a critical factor in MS pathology. In this study, we found that the acrolein scavenger hydralazine (HZ), when applied from the day of induction, can suppress acrolein and alleviate ...
Jonathan Tang +4 more
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Administration of supplemental L-tyrosine with phenelzine: a clinical literature review
Clinical Pharmacology: Advances and Applications, 2014 Marty Hinz,1 Alvin Stein,2 Ted Cole,3 Patricia Ryan4 1Clinical Research, NeuroResearch Clinics, Inc., Cape Coral, FL, USA; 2Stein Orthopedic Associates, Plantation, FL, USA; 3Cole Center for Healing, Cincinnati, OH, USA; 4Family Wellness Center, Omaha ...
Hinz M, Stein A, Cole T, Ryan P
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MAOA inhibitor phenelzine efficacious in recurrent prostate cancer [PDF]
Nature reviews. Urology, 2020 Louise Stone
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