Results 31 to 40 of about 8,267 (256)
Overview of the Neuroprotective Effects of the MAO-Inhibiting Antidepressant Phenelzine
Cellular and molecular neurobiology, 2021 Phenelzine (PLZ) is a monoamine oxidase (MAO)-inhibiting antidepressant with anxiolytic properties. This multifaceted drug has a number of pharmacological and neurochemical effects in addition to inhibition of MAO, and findings on these effects have ...
D. Matveychuk +8 more
semanticscholar +1 more source
Неврология, нейропсихиатрия, психосоматика, 2022 We describe the history of studying of the problem of tyramine syndrome during the treatment with antidepressants, irreversible non-selective monoamine oxidase inhibitors. Data on clinical observations are presented.
D. S. Danilov, M. Yu. Brovko
doaj +1 more source
Обозрение психиатрии и медицинской психологии имени В.М. Бехтерева, 2023 The history of irreversible non-selective MAOI antidepressants in the USSR and Russia is systemized. The history of representatives’ appearance is described. The history of the study of pharmacological effects is highlighted.
D. S. Danilov
doaj +1 more source
Monoamine oxidase inhibitors and neuroprotective mechanisms
Psychiatry and Clinical Psychopharmacology, 2021 There has been a resurgence of interest in recent years in monoamine oxidase inhibitors, primarily because of the demonstrated neuroprotective and/ or neurorescue properties of several of these drugs in a variety of toxic situations in vivo and in vitro.
Glen Baker +4 more
doaj +1 more source
Drug-Related Hypertension: A Disproportionality Analysis Leveraging the FDA Adverse Event Reporting System. [PDF]
J Clin Hypertens (Greenwich)ABSTRACT Hypertension exerts a significant global disease burden, adversely affecting the well‐being of billions. Alarmingly, drug‐related hypertension remains an area that has not been comprehensively investigated. Therefore, this study is designed to utilize the adverse event reports (AERs) from the US Food and Drug Administration's Adverse Event ...
Zhu H, Pan L, Lui H, Zhang J.
europepmc +2 more sources
European Psychiatry, 2022 Introduction Use of Monoamine Oxidase Inhibitors (MAOIs) has experimented an important reduction in recent years, being replaced by other antidepressant drugs (ADs) associated with a better safety profile.
L. Olivier Mayorga +5 more
doaj +1 more source
Clomipramine Induced Extrapyramidal Symptoms: A Case Series [PDF]
Journal of Clinical and Diagnostic Research, 2023 Extra Pyramidal Symptoms (EPS) are a group of symptoms that include dystonia, bradykinesia, tremor, akathisia, and tardive dyskinesia. They are caused by the blockage of D2 receptors in the nigro-striatal pathway and the imbalanced acetyl choline ...
Disha Mukherjee +2 more
doaj +1 more source
A meta-analysis of pharmacotherapy for social anxiety disorder: an examination of efficacy, moderators, and mediators [PDF]
, 2017 INTRODUCTION: Social anxiety disorder (SAD) is among the most prevalent mental disorders, associated with impaired functioning and poor quality of life. Pharmacotherapy is the most widely utilized treatment option.
Borenstein M +8 more
core +2 more sources
HIV-1 infection of microglial cells in a reconstituted humanized mouse model and identification of compounds that selectively reverse HIV latency. [PDF]
, 2017 Most studies of HIV latency focus on the peripheral population of resting memory T cells, but the brain also contains a distinct reservoir of HIV-infected cells in microglia, perivascular macrophages, and astrocytes.
Alvarez-Carbonell, David +4 more
core +1 more source
HR-MS Analysis of the Covalent Binding of Edaravone to 5-Formylpyrimidine Bases and a DNA Oligonucleotide Containing a 5-Formylcytidine Residue. [PDF]
Rapid Commun Mass SpectromABSTRACT Rationale Edaravone (EDA) is a radical scavenger and an antioxidant drug approved to treat amyotrophic lateral sclerosis and used as a research tool to explore treatment of neurodegenerative diseases and cancers. It is also a reactive agent, known as PMP (1‐phenyl‐3‐methyl‐5‐pyrazolone), used for the analysis of polysaccharides composition ...
Regnault R +5 more
europepmc +2 more sources