Results 11 to 20 of about 36,304 (274)

Suspected phenobarbital-induced pancytopenia in a cat

open access: yesJournal of Feline Medicine and Surgery Open Reports, 2020
Case summary A 3-year-old neutered male domestic shorthair cat developed pancytopenia 6 months after starting phenobarbital for treatment of recurrent seizures.
Maria Lyraki, Helen Wilson
doaj   +1 more source

Acute phenobarbital administration induces hyperalgesia: pharmacological evidence for the involvement of supraspinal GABA-A receptors

open access: yesBrazilian Journal of Medical and Biological Research, 2001
The aim of the present study was to determine if phenobarbital affects the nociception threshold. Systemic (1-20 mg/kg) phenobarbital administration dose dependently induced hyperalgesia in the tail-flick, hot-plate and formalin tests in rats and in the ...
C.M. Yokoro   +4 more
doaj   +1 more source

C45 - Hydrogels oraux pH-sensibles contenant du phénobarbital pour une utilisation potentielle en pédiatrie

open access: yesJournal Africain de Technologie Pharmaceutique et Biopharmacie, 2023
Introduction : Le but de l’étude était de développer des hydrogels oraux à base de chitosane pH- sensibles, capables de libérer le phénobarbital dans l'intestin grêle du nouveau-né.
Alphonse Rodrigue DJIBOUNE   +10 more
doaj   +1 more source

Comparing the effect of intermittent diazepam and continuous phenobarbital in preventing recurrent febrile seizures among children under 6 years old: A systematic review and meta-analysis

open access: yesJournal of Research in Medical Sciences, 2023
Background: Febrile convulsion (FC) is the most common and preventable seizure in children. This study aimed to assess the effectiveness of the diazepam and phenobarbital for preventing recurrent FC. Materials and Methods: In this systematic review study,
Leili Faraji Gavgani   +5 more
doaj   +1 more source

Phenobarbital dyskinesia [PDF]

open access: yesPostgraduate Medical Journal, 1978
Summary A patient was admitted to hospital following an overdose of phenobarbital. During her recovery she developed both chorea and torsion dystonia which could only be related to her high plasma phenobarbital levels.
openaire   +2 more sources

Evading Seizures: Phenobarbital Reintroduced as a Multifunctional Approach to End-of-Life Care

open access: yesCase Reports in Oncology, 2022
The selected case study aimed to evaluate the role of phenobarbital as a drug of choice in end-of-life (EOL) settings. Phenobarbital is efficacious in management of EOL seizures and agitation, can be easily administered via different modes, and utilized ...
Helen Senderovich   +2 more
doaj   +1 more source

Comparison between the Amount of Environmental Change and the Amount of Transcriptome Change.

open access: yesPLoS ONE, 2015
Cells must coordinate adjustments in genome expression to accommodate changes in their environment. We hypothesized that the amount of transcriptome change is proportional to the amount of environmental change.
Norichika Ogata   +4 more
doaj   +1 more source

Phenobarbital-induced autoimmune haemolytic anaemia, thrombocytopenia and peripheral lymphadenomegaly due to reactive lymphoid hyperplasia in a cat

open access: yesJournal of Feline Medicine and Surgery Open Reports, 2022
Case summary A female neutered domestic longhair cat, aged 1 year and 5 months, presented with lymphadenomegaly and anaemia following therapy with phenobarbital for idiopathic epilepsy.
Michelle Walton-Clark   +2 more
doaj   +1 more source

Evaluation of Intravenous Phenobarbital Pharmacokinetics in Critically Ill Patients With Brain Injury

open access: yesActa Medica Iranica, 2022
Phenobarbital is still one of the drugs of choice in managing patients with brain injury in the intensive care unit (ICU). However, the impact of acute physiological changes on phenobarbital pharmacokinetic parameters is not well studied.
Seyedeh Sana Khezrnia   +9 more
doaj   +1 more source

Oral Loading of Phenobarbital to Achieve Therapeutic Effects in Pediatric Patients with Acute Repetitive Seizures [PDF]

open access: yesAnnals of Child Neurology, 2023
Purpose Intravenous phenobarbital has not been available at our institution since 2019. This study aimed to determine the effectiveness of oral phenobarbital loading at a dose of 15 to 20 mg/kg to achieve therapeutic serum levels and clinical seizure ...
Jemima Grace D. Fronda   +2 more
doaj   +1 more source

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