Results 11 to 20 of about 86,047 (385)
Exposure to excess phenobarbital negatively influences the osteogenesis of chick embryos [PDF]
Frontiers in Pharmacology, 2016 Phenobarbital is an antiepileptic drug that is widely used to treat epilepsy in a clinical setting. However, a long term of phenobarbital administration in pregnant women may produce side effects on embryonic skeletogenesis.
Yu Yan +8 more
doaj +5 more sources
Epilepsia Open, 2020 Objective Organophosphates (OPs) such as diisopropylfluorophosphate (DFP) and soman are lethal chemical agents that can produce seizures, refractory status epilepticus (SE), and brain damage.
Doodipala Samba Reddy +5 more
doaj +2 more sources
Efficacy of phenobarbital is maintained after exposure to mild‐to‐moderate seizures in neonates [PDF]
Epilepsia OpenTo study the relationship between the delay in treatment and the efficacy of phenobarbital in neonates, we re‐analyzed data from the NEOLEV2 study. Continuous video EEG (cEEG) from patients treated with phenobarbital was reviewed by neurophysiologists ...
Cynthia Sharpe +9 more
doaj +2 more sources
Phenobarbital dyskinesia [PDF]
Postgraduate Medical Journal, 1978 Summary A patient was admitted to hospital following an overdose of phenobarbital. During her recovery she developed both chorea and torsion dystonia which could only be related to her high plasma phenobarbital levels.
S L Lightman
openalex +4 more sources
Frontiers in Neurology, 2019 Introduction: Pediatric convulsive status epilepticus (CSE) which is refractory to first-line benzodiazepines is a significant clinical challenge, especially within resource-limited countries.
Richard J. Burman +8 more
doaj +2 more sources
Bumetanide Enhances Phenobarbital Efficacy in a Rat Model of Hypoxic Neonatal Seizures [PDF]
PLoS ONE, 2013 Neonatal seizures can be refractory to conventional anticonvulsants, and this may in part be due to a developmental increase in expression of the neuronal Na+-K+-2 Cl− cotransporter, NKCC1, and consequent paradoxical excitatory actions of GABAA receptors
Berry, Gerard T. +11 more
core +4 more sources
Phenobarbital: missing in action.
Bulletin of the World Health Organization, 2012 Epilepsy affects more than 60 million people worldwide, and over 80% of them live in resource-poor countries.1 Approximately 85% of these people do not receive appropriate treatment2 because of economic, cultural, social and legislative barriers ...
Neshan B Ilangaratne +3 more
semanticscholar +4 more sources
Phenobarbital versus benzodiazepines in alcohol withdrawal syndrome
Neuropsychopharmacology Reports, 2023 Aim Phenobarbital, a long‐acting barbiturate, presents an alternative to conventional benzodiazepine treatment for alcohol withdrawal syndrome (AWS).
Deanna Malone +5 more
doaj +1 more source
Levetiracetam Versus Phenobarbital for Neonatal Seizures: A Randomized Controlled Trial
Pediatrics, 2020 This phase IIb randomized controlled trial demonstrates greater efficacy of phenobarbital than levetiracetam in the treatment of neonatal seizures; more adverse events occurred with phenobarbital.
Cynthia Sharpe +24 more
semanticscholar +1 more source
Evaluation of Prophylactic and Therapeutic Effects of Silymarin on Phenobar- bital-Induced Hepatotoxicity in Cats [PDF]
Iranian Journal of Veterinary Medicine, 2020 BACKGROUND: Phenobarbital is one of the most commonly used drugs to treat epilepsy and other seizure disorders in dogs and cats. Hepatotoxicity following phenobarbital administration is dose-dependent.
Bahman Mosallanejad +3 more
doaj +1 more source