Results 11 to 20 of about 55,451 (338)

Phenobarbital dyskinesia [PDF]

Postgraduate Medical Journal, 1978
Summary A patient was admitted to hospital following an overdose of phenobarbital. During her recovery she developed both chorea and torsion dystonia which could only be related to her high plasma phenobarbital levels.
S L Lightman
openaire   +4 more sources

Toxic epidermal necrolysis caused by phenobarbital: a case report and literature review [PDF]

Frontiers in Pharmacology
BackgroundToxic epidermal necrolysis (TEN) and Stevens-Johnson syndrome (SJS) are rare, life-threatening immunologic reactions. Previous relevant literature has provided limited information regarding this disease’s genetic susceptibility and management ...
Jie Cheng, Jie Cheng, Hui Li, Yan Li, Xiao Li, Jianjun Wang, Xin Huang, XueYan Cui   +7 more
doaj   +2 more sources

Does long‐term phenytoin have a place in Dravet syndrome?

Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 2036-2040, December 2022., 2022
Abstract Anti‐seizure medications that block sodium channels are generally considered contraindicated in Dravet syndrome. There is, however, considerable debate about the sodium‐channel blocker phenytoin, which is often used for status epilepticus, a frequent feature of Dravet syndrome.
George A. Zographos, Sophie J. Russ‐Hall, Ingrid E. Scheffer   +2 more
wiley   +1 more source

The Evidence Behind the Treatment of Canine Idiopathic Epilepsy [PDF]

, 2016
Oral phenobarbital and imepitoin in particular, followed by potassium bromide and levetiracetam are likely to be effective for the treatment of canine idiopathic epilepsy. There is strong evidence supporting the use of oral phenobarbital and imepitoin as
Brodbelt, D C, Charalambous, M, Volk, H A   +2 more
core   +3 more sources

Comparing the effect of intermittent diazepam and continuous phenobarbital in preventing recurrent febrile seizures among children under 6 years old: A systematic review and meta-analysis

Journal of Research in Medical Sciences, 2023
Background: Febrile convulsion (FC) is the most common and preventable seizure in children. This study aimed to assess the effectiveness of the diazepam and phenobarbital for preventing recurrent FC. Materials and Methods: In this systematic review study,
Leili Faraji Gavgani, Delara Laghousi, Parvin Sarbakhsh, Leila Jahangiri, Nafiseh Vahed, Sakineh Hajebrahimi   +5 more
doaj   +1 more source

2015 ACVIM Small Animal Consensus Statement on Seizure Management in Dogs [PDF]

, 2016
This report represents a scientific and working clinical consensus statement on seizure management in dogs based on current literature and clinical expertise.
Bunch SE, Bunch SE, Cheuk DK, Cunningham JG, Dayrell‐Hart B, Durkes TE, Dyer KR, E.E. Patterson, Farnbach GC, Farnbach GC, Forrester SD, Frey HH, Gaskill CL, Gaskill CL, H.A. Volk, Jacobs G, Jennings PB, K. Muñana, Kantrowitz LB, M. Berendt, M. Podell, March PA, Masuda Y, Nichols ES, Patterson E, Pearce L, Pedersoli WM, Perrucca E, Poffenbarger EM, Ravis WR, S.R. Platt, Schwartz‐Porsche D, Schwartz‐Porsche D, Steinberg M, Thurman GD, Trepanier LA, Trepanier LA, W. Löscher   +37 more
core   +2 more sources

Acute phenobarbital administration induces hyperalgesia: pharmacological evidence for the involvement of supraspinal GABA-A receptors

Brazilian Journal of Medical and Biological Research, 2001
The aim of the present study was to determine if phenobarbital affects the nociception threshold. Systemic (1-20 mg/kg) phenobarbital administration dose dependently induced hyperalgesia in the tail-flick, hot-plate and formalin tests in rats and in the ...
C.M. Yokoro, S.M.S. Pesquero, R.M.M. Turchetti-Maia, J.N. Francischi, M.A.K.F. Tatsuo   +4 more
doaj   +1 more source

Evading Seizures: Phenobarbital Reintroduced as a Multifunctional Approach to End-of-Life Care

Case Reports in Oncology, 2022
The selected case study aimed to evaluate the role of phenobarbital as a drug of choice in end-of-life (EOL) settings. Phenobarbital is efficacious in management of EOL seizures and agitation, can be easily administered via different modes, and utilized ...
Helen Senderovich, Sarah Waicus, Keisa Mokenela   +2 more
doaj   +1 more source

Antiepileptic drugs’ tolerability and safety – a systematic review and meta-analysis of adverse effects in dogs [PDF]

, 2016
Various anti-epileptic drugs (AEDs) are used for the management of idiopathic epilepsy (IE) in dogs. Their safety profile is an important consideration for regulatory bodies, owners and prescribing clinicians.
A Stabile, A-MOL-V Kiviranta, AA Shukralla, AE Chauvet, AK Cook, AS Nash, B Dayrell-Hart, B Mackay, C Rundfeldt, CL Gaskill, CL Gaskill, CR Hooijmans, D Moher, D Ruehlmann, D Schwartz-Porsche, D Schwartz-Porsche, David C. Brodbelt, DE Bevier, DJ Meyer, DJ Weiss, DJ Weiss, DJU Schwartz-Porsche, DM Boothe, DM Boothe, DM Conning, E Bersan, E Ernst, E Perucca, E Thrift, EM Poffenbarger, F Sturtevant, G Habock, G Jacobs, G Zaccara, G Zaccara, GC Farnbach, HA Volk, HE Baird-Heinz, Holger A. Volk, J Speciale, JA Berlin, JC Mathis, JF Summers, JG Cunningham, JH McGee, JH Rossmeisl, JK Aronson, JM Steiner, KR Dyer, L Aagaard, LAPA Nafe, LB Kantrowitz, LC Paull, LG Cuervo, LK Pearce, M Charalambous, M Govendir, M Jambroszyk, M Podell, M Raw, M Srivastava, MA Holmes, Marios Charalambous, MFD Steinberg, MH Litchfield, ML Miller, MM Aitken, N Andric, N Shaw, NA Boynosky, PA March, PB Muller, PM Henricks, PN Papanikolaou, PN Papanikolaou, R Bracchi, R Chou, RM Turner, RM Walker, S Daminet, S Derry, S Golder, S Golder, S Rieck, S Steinmetz, S Wieland, SA Kube, SA Moore, Sara K. Shivapour, SD Ross, SE Bunch, SE Bunch, SE Bunch, SE Bunch, SE Yohn, SF Foster, T Klopmann von, T Klopmann von, T Klopmann von, VJ Navarro, W Loscher, W Loscher, Y Chang, Y Heynold, YK Loke, YK Loke   +105 more
core   +3 more sources

Revisiting phenobarbital for epilepsy [PDF]

BMJ, 2004
A recent review of phenobarbital for the treatment of epilepsy draws attention to an ethical dilemma and to the many gaps in our knowledge about a drug that has been in use since 1912.1 Phenobarbital is commonly prescribed in the developing world, but in most developed countries it has fallen into disrepute.
PERUCCA, EMILIO, Kale R.
openaire   +4 more sources