Results 21 to 30 of about 55,451 (338)

Evaluation of Intravenous Phenobarbital Pharmacokinetics in Critically Ill Patients With Brain Injury

Acta Medica Iranica, 2022
Phenobarbital is still one of the drugs of choice in managing patients with brain injury in the intensive care unit (ICU). However, the impact of acute physiological changes on phenobarbital pharmacokinetic parameters is not well studied.
Seyedeh Sana Khezrnia, Bita Shahrami, Mohammad Reza Rouini, Atabak Najafi, Hamid Reza Sharifnia, Sima Sadrai, Arezoo Ahmadi, Aarefeh Jafarzadeh kohneloo, Farhad Najmeddin, Mojtaba Mojtahedzadeh   +9 more
doaj   +1 more source

Systematic review of antiepileptic drugs’ safety and effectiveness in feline epilepsy [PDF]

, 2018
Understanding the efficacy and safety profile of antiepileptic drugs (AEDs) in feline epilepsy is a crucial consideration for managing this important brain disease.
A Klang, A Pakozdy, A Pakozdy, A Pakozdy, A Pellegrini, AD Quesnel, Akos Pakozdy, AM Wahle, AS Sawchuk, C Bertolani, CR Hooijmans, CW Dewey, D Hasegawa, D Hughes, D Moher, D Schwartz-Porsche, D Schwartz-Porsche, DB Roye, DE Cuff, DL Zoran, DM Boothe, DM Brewer, G Zaccara, G Zaccara, GE Solomon, GH Guyatt, H Volk, Holger A. Volk, JA Berlin, JA Wada, JAD Gasper, JM Ducote, KE Finnerty, KS Bailey, KS Bailey, LR Barnard, M Charalambous, M Charalambous, M Lowrie, M Podell, MA Cautela, MA Holmes, Marios Charalambous, MB Carnes, MJ Baho, NM van Gelder, O Engel, P Boydell, PN Papanikolaou, R Chou, S Cizinauskas, S Schriefl, S Wagner, SA Center, SD Ross, SF Bhatti, SM Cochrane, SM Cochrane, Sofie F. M. Bhatti   +58 more
core   +2 more sources

The effectiveness of continuous venovenous hemodiafiltration in phenobarbital intoxication

Acta Medica International, 2018
Phenobarbital continues to be widely used in childhood epilepsy. Incorrect drug prescription can sometimes lead to intoxication, particularly in young children.
Yasemin Çoban, Dinçer Yildizdas, Özden Özgür Horoz, Nagehan Aslan, Didar Arslan   +4 more
doaj   +1 more source

Phenobarbital-induced autoimmune haemolytic anaemia, thrombocytopenia and peripheral lymphadenomegaly due to reactive lymphoid hyperplasia in a cat

Journal of Feline Medicine and Surgery Open Reports, 2022
Case summary A female neutered domestic longhair cat, aged 1 year and 5 months, presented with lymphadenomegaly and anaemia following therapy with phenobarbital for idiopathic epilepsy.
Michelle Walton-Clark, Victoria Travail, Matthew Best   +2 more
doaj   +1 more source

Neonatal abstinence syndrome: Pharmacologic strategies for the mother and infant. [PDF]

, 2016
Opioid use in pregnancy has increased dramatically over the past decade. Since prenatal opioid use is associated with numerous obstetrical and neonatal complications, this now has become a major public health problem.
Davis, Jonathan M., Kraft, Walter K., Stover, Megan W.   +2 more
core   +2 more sources

Ursodeoxycholic acid versus phenobarbital for cholestasis in the Neonatal Intensive Care Unit

BMC Pediatrics, 2018
Background Although neonates and young infants with cholestasis are commonly treated with either phenobarbital or ursodeoxycholic acid (ursodiol), there is no evidence that phenobarbital is effective for this indication.
Tamorah Lewis, Simisola Kuye, Ashley Sherman   +2 more
doaj   +1 more source

Human targeted phenobarbital presents a poor substrate of gut microbiome deciphering new drug targets beyond pharmacokinetic curbs

BMC Pharmacology and Toxicology, 2022
Background The gut microbiome, a new organ of the body, can potentially alter the pharmacokinetics of orally administered drugs through microbial enzymes.
Imran Mukhtar, Haseeb Anwar, Arslan Iftikhar, Heba E. Hashem, Qasim Ali, Farhan Siddique   +5 more
doaj   +1 more source

Measurement of Blood Phenobarbital Concentration in Newborns Admitted to The NICU of Imam Reza Hospital and Receiving The Drug Via Intravenous Mode [PDF]

Asia Pacific Journal of Medical Toxicology
Introduction: Newborns may be treated with phenobarbital for many reasons. Because in each region, depending on different races and genetic factors, different pharmacokinetic conditions govern the drug.
Hamidreza Goldouzi, Ashraf Mohammadzadeh, Ahmadshah Farhat, Anahita Alizadeh, F Yazdanpanah, Tina Loghmani, Ezzat Khodashenas   +6 more
doaj   +1 more source

Interventions for treating hyperemesis gravidarum. [PDF]

, 2016
BACKGROUND: Hyperemesis gravidarum is a severe form of nausea and vomiting in pregnancy affecting 0.3% to 1.0% of pregnancies, and is one of the most common indications for hospitalization during pregnancy.
Abas, Adamczak, Arsenault, Bailit, Bondok, Bowen, Capp, Carlsson, Cox, Ditto, Dodds, Duggar, Eftekhari, Eliakim, Erez, Fell, Ferruti, Fischer-Rasmussen, Fletcher, Fletcher, Gadsby, Gawande, Gill, Goodwin, Gordon, Habek, He, Heazell, Holmgren, Ismail, Jarvis, Kashifard, Kelly, Klebanoff, Koren, Koren, Koren, Koren, Kramer, Lask, Ling, Liu, Magee, Maina, Maltepe, Maltepe, Mao, Mao, Matok, Matok, Matthews, Mazzotta, McCarthy, McCarthy, McParlin, Mella, Miller, Moran, Munch, Nelson-Piercy, Neri, Neutel, Niebyl, Oliveira, Ozgoli, Pasternak, Philip, Piwko, Pongrojpaw, Poursharif, Poursharif, Power, Price, Rhodes, Rhodes, Rosen, Safari, Safari, Saha, Shin, Shin, Sonkusare, Sullivan, Sullivan, Swallow, Tabatabaii, Tan, Tan, Tan, Tasci, Veciana, Wibowo, Willetts, Ylikorkala, Yost, Zhou, Ziaei   +96 more
core   +2 more sources

Phenobarbital, midazolam pharmacokinetics, effectiveness, and drug-drug interaction in asphyxiated neonates undergoing therapeutic hypothermia [PDF]

, 2019
Background: Phenobarbital and midazolam are commonly used drugs in (near-)term neonates treated with therapeutic hypothermia for hypoxic-ischaemic encephalopathy, for sedation, and/or as anti-epileptic drug. Phenobarbital is an inducer of cytochrome P450
Bos, Annelies A., Brouwer, Mieke J., Camfferman, Fleur Anne, Cools, Filip, de Haan, Timo R., de Jonge, Rogier C. J., Dijk, Peter H., Dijkman, Koen P., Dudink, Jeroen, Egberts, Toine C. G., Favie, Laurent M. A., Groenendaal, Floris, Huitema, Alwin D. R., Jebbink-Akkerman, L. J. M. Groot, Liem, Djien, Mulder-de Tollenaer, S. M., Nuytemans, Debbie H. G. M., Rademaker, Carin M. A., Rijken, Monique, Simons, Sinno H. P., Sonnaert, Michel, Steiner, Katerina, van Bel, Frank, van den Broek, Marcel P. H., van der Lee, Johanna H., van Heijst, Arno, van Straaten, Henrica L. M., Zecic, Aleksandra, Zonnenberg, Inge A.   +28 more
core   +2 more sources